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New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Targeting senescent cells in the retina with a BCL-xL inhibitor shows promise as a durable treatment for diabetic macular edema, potentially offering long-term visual function improvements.

8 Feb 2024

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

A new research perspective was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma."

8 Feb 2024

Study tracks health and quality of life in chronically critically ill COVID-19 patients months after hospital discharge

Researchers investigated chronic critical illness in COVID-19 survivors who sought ICU admission and were on mechanical ventilation due to severe infection by SARS-CoV-2.

8 Feb 2024

ELRIG UK announces Steve Bates and Dr Anderson Ryan as keynote speakers at Research and Innovation 2024

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the keynote speakers for its upcoming Research and Innovation conference taking place at the University of Manchester from 20–21 March.

From ELRIG (UK) Ltd. 8 Feb 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

AMG 133, an engineered bispecific molecule, demonstrated significant weight loss with a favorable safety profile in a phase 1 clinical trial, offering a promising new treatment option for obesity.

7 Feb 2024

Experimental mRNA vaccine against CMV elicits promising immune responses

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

7 Feb 2024

New analysis demonstrates a link between air pollution and cardiovascular disease-related deaths

A recent analysis of data from nearly all World Health Organization member states clearly demonstrates a link between air pollution and mortality from cardiovascular diseases, with more of such deaths associated with air pollution in low-income countries compared with high-income countries.

7 Feb 2024

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Whether higher dietary niacin intake lowers the risk of all-cause, heart and cerebrovascular disease(s).

6 Feb 2024

Pomegranate seed oil boosts brain function in mild cognitive impairment study

Study demonstrates that pomegranate seed oil (PSO) combined with the Mediterranean Diet (MeDi) significantly enhances cognitive functions in individuals with mild cognitive impairment (MCI), suggesting PSO as a potential natural intervention for cognitive health.

5 Feb 2024

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

Study demonstrates Resveratrol's ability to mitigate Alzheimer's Disease (AD) symptoms by inhibiting proinflammatory responses and promoting antioxidant enzyme expression in microglial cell lines, offering insights into its neuroprotective mechanisms.

5 Feb 2024

SLAS 2024 press release from Veranex

Veranex provider of the first purpose-built, global service platform for the medtech industry, today announced that it has acquired T3 Labs, a highly reputable preclinical laboratory located in Atlanta, Georgia. This acquisition solidifies Veranex’s commitment to expanding its preclinical footprint in North

5 Feb 2024

Study links specific inflammatory markers to increased cancer risk

The causal relevance of circulating inflammatory markers in cancer risk.

5 Feb 2024

Revvity showcases cutting-edge solutions at SLAS2024

Revvity presents its continued commitment to expanding the boundaries of human potential through science.

From Revvity 5 Feb 2024

UVA scientists develop new approach to machine learning for identifying heart drug

University of Virginia scientists have developed a new approach to machine learning – a form of artificial intelligence – to identify drugs that help minimize harmful scarring after a heart attack or other injuries.

5 Feb 2024

Breakthrough obesity treatments on the horizon, rivaling surgery's success

New obesity pharmacotherapies, including GLP-1 receptor agonists and combinations of entero-pancreatic hormones, show promise in achieving significant weight loss, potentially rivaling bariatric surgery's effectiveness.

4 Feb 2024

New methods for heart monitoring could transform cardiovascular care

Chocolate valentines and candies with sweet sayings shouldn't be the only hearts you think about this February.

1 Feb 2024

Researchers discover new class of compound that targets cancer stem cells

Many cancer therapies, in addition to producing numerous side effects, fail to achieve complete tumour remission, partly due to the presence of cancer stem cells, which are difficult to eradicate.

31 Jan 2024

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

Personalized therapies could improve the treatment of many diseases in the future. Cancer medicine in particular has made significant progress in recent years.

31 Jan 2024

CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Joseph Parisi as US Director of Sales. In his new role, Joe will lead the expansion of the Company’s sales and support activities for the US market to address the growing demand for new alternative methodologies (NAMs) in preclinical drug discovery.

31 Jan 2024

Preclinical News and Research

New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Hope for relapsed myeloma: Preclinical and clinical evidence for ruxolitinib's efficacy

Study tracks health and quality of life in chronically critically ill COVID-19 patients months after hospital discharge

ELRIG UK announces Steve Bates and Dr Anderson Ryan as keynote speakers at Research and Innovation 2024

AMG 133 (maridebart cafraglutide) weight loss drug shows promise in early trial

Experimental mRNA vaccine against CMV elicits promising immune responses

New analysis demonstrates a link between air pollution and cardiovascular disease-related deaths

Patients with non-alcoholic fatty liver disease may benefit from increased dietary niacin intake

Pomegranate seed oil boosts brain function in mild cognitive impairment study

Resveratrol can combat Alzheimer's via inflammatory suppression, study shows

SLAS 2024 press release from Veranex

Study links specific inflammatory markers to increased cancer risk

Revvity showcases cutting-edge solutions at SLAS2024

UVA scientists develop new approach to machine learning for identifying heart drug

Breakthrough obesity treatments on the horizon, rivaling surgery's success

New methods for heart monitoring could transform cardiovascular care

Researchers discover new class of compound that targets cancer stem cells

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

AI-based applications for personalized cancer medicine and related regulatory challenges: An overview

CN Bio appoints Joseph Parisi as US Director of Sales to support accelerated growth in key OOC market

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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