Progesterone News and Research

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Clearblue Digital Ovulation test safe, non-invasive for women trying to conceive

Dr. Jayne Ellis, Director of Scientific and Medical Affairs at SPD Swiss Precision Diagnostics GmbH, Geneva, Switzerland, makers of the test, explained that it consisted of a digital reader and urine test sticks, which could detect the surge in luteinising hormone (LH) that triggers ovulation.

5 Jul 2011

Study: Threatened miscarriages complicate 20% of all pregnancies

Dr Kaltum Adam, an honorary clinical research fellow at St Mary's Hospital in Manchester (UK), told the annual meeting of the European Society for Human Reproduction and Embryology that around 20% of all pregnancies were complicated by threatened miscarriage, and up to 20% of these would miscarry.

5 Jul 2011

FDA accepts for filing Columbia's PROCHIEVE progesterone gel NDA

Columbia Laboratories, Inc. and Watson Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing Columbia's New Drug Application (NDA) for PROCHIEVE (progesterone gel) for the reduction of risk of preterm birth in women with short uterine cervical length in the mid-trimester of pregnancy.

27 Jun 2011

Centrix and CutisPharma enter promotional agreement for vaginal suppository compounding kits

Centrix Pharmaceutical, Inc., a privately-held specialty pharmaceutical company focused on Pediatrics and Women's Health, announces a promotional agreement with CutisPharma, Inc., a Woburn, Massachusetts based company.

23 Jun 2011

Cervical ripening that instigates preterm birth is distinct from normal term labor

Cervical ripening that instigates preterm labor is distinct from what happens at the onset of normal term labor, researchers at UT Southwestern Medical Center have found.

18 Jun 2011

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Synta Pharmaceuticals Corp. today presented results at the Annual Meeting of the American Society for Clinical Oncology (ASCO) from a Phase 2 single agent clinical trial of ganetespib in gastrointestinal stromal tumors (GIST) and a Phase 1 trial of ganetespib in solid tumors evaluating a twice-weekly administration schedule.

7 Jun 2011

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Estrogen therapy improves low bone density due to anorexia nervosa in teenage girls with the disease when given as a patch or as a low oral dose that is physiological.

6 Jun 2011

Starving breast cancer cells of hedgehog significantly slows tumour growth and spread

While it is already known that breast cancer cells create the conditions for their own survival by communicating their needs to the healthy cells that surround them, Australian researchers have identified a new way of turning off that cellular cross talk.

4 Jun 2011

Researcher to evaluate new approach for treatment of triple-negative breast cancer

A multicenter clinical trial led by a researcher at the University of Maryland Marlene and Stewart Greenebaum Cancer Center will evaluate a new approach to treat triple-negative breast cancer, an often-aggressive type of cancer that is more common among African-Americans and young women.

4 Jun 2011

Researchers discover overactive genes that drive triple-negative breast cancer cells

Scientists at Dana-Farber Cancer Institute have identified an overactive network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors, a typically aggressive cancer that is highly resistant to current therapies.

2 Jun 2011

EMAS publishes position statement on women's post-reproductive health problems in Maturitas journal

Elsevier announced the publication of an important position statement from the European Menopause and Andropause Society in the journal Maturitas on managing menopausal women with a personal or family history of venous thromboembolism.

18 May 2011

Columbia Laboratories to be listed on NASDAQ Biotechnology Index

Columbia Laboratories, Inc. today announced the Company will be added to the NASDAQ Biotechnology Index.

17 May 2011

Gene variant linked to infertility in women

A variation in a gene involved in regulating cholesterol in the bloodstream also appears to affect progesterone production in women, making it a likely culprit in a substantial number of cases of their infertility, a new study from Johns Hopkins researchers suggests.

16 May 2011

ETI finalizes proprietary progesterone formulations for Traumatic Brain Injury

Encore Therapeutics, Inc. today reported finalizing its proprietary phospholipid nanoemulsion formulation of progesterone.

12 May 2011

Columbia Laboratories net revenues increase 74% to $12.5 million

Columbia Laboratories, Inc. today reported financial results for the three-month period ended March 31, 2011.

5 May 2011

Researchers identify unexpected triple-negative breast cancer marker

German researchers have identified an unexpected molecular marker that predicts how sensitive hard-to-treat triple-negative breast cancers are to chemotherapy.

5 May 2011

Researchers discover new mechanism by which BRCA1 gene mutations can induce breast cancer

Two researchers from the Centre for Genomic Regulation in Barcelona have discovered a new mechanism by which mutations in gene BRCA1 can induce breast cancer.

5 May 2011

Columbia requests FDA Priority Review for PROCHIEVE progesterone gel NDA

Columbia Laboratories, Inc., and Watson Pharmaceuticals, Inc., today announced that Columbia has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for PROCHIEVE® (progesterone gel) for the reduction of risk of preterm birth in women with short uterine cervical length in the mid-trimester of pregnancy.

27 Apr 2011

Newer birth control pill raises risk of blood clots

Two human trials in the US and the UK including women from both populations showed that women taking newer forms of oral contraceptives, which include drosperinone, a synthetic version of the hormone progesterone, increased their risk of developing a blood clots by two or three times over those taking older birth control pills that rely on a different form of the hormone known as levonorgestrel.

26 Apr 2011

Changes in hormonal status have no impact on women's voice parameters

In recent years several studies have suggested that women's voices change at different times over the menstrual cycle, with the tone rising as ovulation approaches. Now a study conducted by researchers at the West Texas A&M University in which women's voices were subjected to computerized acoustical analysis contradicts those findings.

12 Apr 2011

Progesterone News and Research

Clearblue Digital Ovulation test safe, non-invasive for women trying to conceive

Study: Threatened miscarriages complicate 20% of all pregnancies

FDA accepts for filing Columbia's PROCHIEVE progesterone gel NDA

Centrix and CutisPharma enter promotional agreement for vaginal suppository compounding kits

Cervical ripening that instigates preterm birth is distinct from normal term labor

Synta presents ganetespib Phase 1, 2 trial results against solid tumors at ASCO 2011

Estrogen therapy improves low bone density in teenage girls with anorexia nervosa

Starving breast cancer cells of hedgehog significantly slows tumour growth and spread

Researcher to evaluate new approach for treatment of triple-negative breast cancer

Researchers discover overactive genes that drive triple-negative breast cancer cells

EMAS publishes position statement on women's post-reproductive health problems in Maturitas journal

Columbia Laboratories to be listed on NASDAQ Biotechnology Index

Gene variant linked to infertility in women

ETI finalizes proprietary progesterone formulations for Traumatic Brain Injury

Columbia Laboratories net revenues increase 74% to $12.5 million

Researchers identify unexpected triple-negative breast cancer marker

Researchers discover new mechanism by which BRCA1 gene mutations can induce breast cancer

Columbia requests FDA Priority Review for PROCHIEVE progesterone gel NDA

Newer birth control pill raises risk of blood clots

Changes in hormonal status have no impact on women's voice parameters

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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