Prostate Specific Antigen News and Research

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Magnetic resonance imaging to help diagnose hidden prostate cancer

Clinical researchers at Princess Margaret Hospital (PMH) can now answer the question that baffles many clinicians - why do some men with elevated prostate specific antigen (PSA) levels who are carefully monitored and undergo repeated negative biopsies still develop aggressive prostate cancer?

9 Oct 2009

PSA test vital for assessing prostate cancer

When it comes to the prostate cancer, the disease known as the "silent killer" because it often exhibits no symptoms, to be forewarned is to be forearmed. It is the second leading cancer killer in men, just behind lung cancer. Every year, more than 218,000 men are diagnosed with prostate cancer in the United States, claiming about 28,000 lives.

1 Oct 2009

Effective decision support tools may help decide whether or not to undertake PSA screening

Although screening for prostate cancer with the Prostate Specific Antigen (PSA) test in men ages 50-70 can detect the cancer before it becomes symptomatic, knowing whether screening is beneficial for these men is uncertain.

30 Sep 2009

Acrux reports Phase III trial results evaluating AXIRON for testosterone deficiency

Australian company, Acrux, today announced positive results from a Phase III trial evaluating the safety and efficacy of AXIRON™ in 155 men with testosterone deficiency (hypogonadism), across 26 sites in six countries.

29 Sep 2009

Statistical modeling used to estimate benefits and risks of PSA screening

Men largely make decisions about prostate cancer screening based on conversations with their clinicians, but these discussions often do not include information about the risks of testing in addition to the benefits, according to a report in the September 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

29 Sep 2009

Radiation treatment after prostate cancer surgery eradicates recurrent cancer

The largest single-institution study of its kind has found few complications in prostate cancer patients treated with radiotherapy after surgery to remove the prostate. Men in this study received radiotherapy after a prostate-specific antigen (PSA) test following surgery indicated their cancer had recurred.

29 Sep 2009

Medivation commences patient treatment in clinical trial of MDV3100 in advanced prostate cancer

Medivation, Inc. (Nasdaq: MDVN) today announced treatment of the first patient in a Phase 3 clinical trial of the investigational drug MDV3100 in advanced prostate cancer. Known as AFFIRM, the trial will evaluate the novel androgen receptor antagonist MDV3100 in men with castration-resistant prostate cancer who were previously treated with docetaxel-based chemotherapy.

24 Sep 2009

ColoMarker assay achieves 100 percent detection rate for colon cancers

Marking a major milestone in the early detection and management of colon cancer, EDP Biotech Corporation (EDP), a developer of immunodiagnostic tests for humans and animals, announced today that its ColoMarker assay achieved 100 percent detection rate for colon cancers presented at stages I through III in pre-clinical trials.

17 Sep 2009

PCEC to provide free prostate cancer screenings

This September, the Prostate Conditions Education Council reminds men to set aside 10 minutes to take lifesaving measures. In just 10 minutes, the same amount of time it takes to shave their faces, men can be screened for prostate cancer, the second leading cause of death among American men. For one week this month the Prostate Conditions Education Council (PCEC) will be coordinating Prostate Cancer Awareness Week (PCAW), which provides free or low-cost screenings to thousands of men across the United States.

16 Sep 2009

Research study investigates survival rates of prostate cancer patients across time periods

New research to be published in tomorrow's issue of the Journal of the American Medical Association (JAMA) (Vol. 302, No. 11), by a team at The Cancer Institute of New Jersey (CINJ), shows that men diagnosed with prostate cancer beginning in the early 1990's had significantly improved survival outcomes compared with patients whose cancers were diagnosed in prior decades.

16 Sep 2009

GENova to file for Prostaganin patents in the US and in Europe

GENova Biotherapeutics Inc. ("GENova") today announced that it is preparing for patent application filings in both the US (at the FDA (U.S. Food and Drug Administration (www.fda.gov) for a 510(k) submission) and in Europe through EMEA (European Medicines Agency) subsequent to expected efficacious and non-toxic pre-clinical results for Prostaganin.

14 Sep 2009

GENova Biotherapeutics to obtain three new drug target patents

GENova Biotherapeutics, Inc., ("GENova"), a biotechnology company that develops novel therapeutic proteins that disrupt the advance of life-threatening diseases, is pleased to announce that it is in the process of acquiring three promising new drug target patents that could generate over a billion dollar in royalty fees in the mid to long term.

11 Sep 2009

Protox' Phase 2 study of PRX302 for treating BPH provides positive results

Protox Therapeutics Inc. (TSX: PRX), a leader in the development of receptor targeted fusion proteins, today announced positive 12 month data from its open-label Phase 2 study of PRX302 in males with moderate to severe benign prostatic hyperplasia (BPH). The study results indicate that those patients who received an optimal dose of PRX302 continued to demonstrate significant symptomatic relief at 12 months following a single treatment.

10 Sep 2009

Patient enrollment for Phase 2b study of PRX302 completed by Protox Therapeutics

Protox Therapeutics Inc. (TSX: PRX), a leader in the development of receptor targeted fusion proteins, today announced that it has completed patient enrollment in its multi-centre, double-blinded, placebo controlled Phase 2b study of PRX302 (study name: TRIUMPH) in males with moderate to severe benign prostatic hyperplasia (BPH), a common and bothersome urological condition that affects more than 50 million men worldwide.

8 Sep 2009

Dr. Samadi of the Mount Sinai Medical Center stresses on prostate cancer awareness

September signifies the start of fall, back to school and back to homework. September is also National Prostate Cancer Awareness Month. The awareness month was proclaimed by President Bush in 2003, and bolstered later that year by former New York mayor Rudy Giuliani, a prostate cancer survivor, who became the spokesman for the National Prostate Cancer Coalition.

2 Sep 2009

New findings on molecular imaging and prostate cancer

A new study published in the September issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET)/computer tomography (CT) scans with the imaging agent choline could detect recurring prostate cancer sooner than conventional imaging technologies in some patients who have had their prostates surgically removed.

2 Sep 2009

Gen-Probe commences its PROGENSA PCA3 assay clinical trial

Gen-Probe Incorporated announced today that the Company has begun a clinical trial intended to secure U.S. regulatory approval of its PROGENSA(R) PCA3 assay, a new molecular test that may help determine the need for a repeat prostate biopsy.

28 Aug 2009

Gen-Probe commences clinical study to secure U.S. approval of the PROGENSA PCA3 assay

DiagnoCure Inc. (TSX: CUR) announced that Gen-Probe, Inc. (NASDAQ: GPRO), its partner for the development and commercialization of the PCA3 prostate cancer test, has confirmed today the beginning of a U.S. clinical study intended to secure U.S. regulatory approval of the PROGENSA(R) PCA3 assay, a new molecular test that may help determine the need for a repeat prostate biopsy.

28 Aug 2009

Most people overestimate the life-saving benefits of breast and prostate cancer screening

A public survey conducted in Europe found that the vast majority of people overestimate the life-saving benefits of breast and prostate cancer screening, according to a new study published online August 12 in the Journal of the National Cancer Institute.

12 Aug 2009

Importance of PSA testing in high-risk men, stressed by National Comprehensive Cancer Network

The National Comprehensive Cancer Network (NCCN) recently updated the NCCN Guidelines for Prostate Cancer Early Detection incorporating the results of the recent ERSPC trial that assessed the benefit of PSA screening. The NCCN Guidelines contend that PSA screening does save lives when performed intelligently in men at high-risk of developing the disease.

11 Aug 2009

Prostate Specific Antigen News and Research

Magnetic resonance imaging to help diagnose hidden prostate cancer

PSA test vital for assessing prostate cancer

Effective decision support tools may help decide whether or not to undertake PSA screening

Acrux reports Phase III trial results evaluating AXIRON for testosterone deficiency

Statistical modeling used to estimate benefits and risks of PSA screening

Radiation treatment after prostate cancer surgery eradicates recurrent cancer

Medivation commences patient treatment in clinical trial of MDV3100 in advanced prostate cancer

ColoMarker assay achieves 100 percent detection rate for colon cancers

PCEC to provide free prostate cancer screenings

Research study investigates survival rates of prostate cancer patients across time periods

GENova to file for Prostaganin patents in the US and in Europe

GENova Biotherapeutics to obtain three new drug target patents

Protox' Phase 2 study of PRX302 for treating BPH provides positive results

Patient enrollment for Phase 2b study of PRX302 completed by Protox Therapeutics

Dr. Samadi of the Mount Sinai Medical Center stresses on prostate cancer awareness

New findings on molecular imaging and prostate cancer

Gen-Probe commences its PROGENSA PCA3 assay clinical trial

Gen-Probe commences clinical study to secure U.S. approval of the PROGENSA PCA3 assay

Most people overestimate the life-saving benefits of breast and prostate cancer screening

Importance of PSA testing in high-risk men, stressed by National Comprehensive Cancer Network

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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