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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Shuganjieyu capsule effectively reverses depressive by increasing neurotrophic factor

Shuganjieyu capsule has been approved for clinical treatment by the State Food and Drug Administration of China since 2008. In the clinic, Shuganjieyu capsule is often used to treat mild to moderate depression.

21 Aug 2014

Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

Not every cell in the body is the same genetically, and disease-causing mutations don't necessarily affect every cell—making these mutations easy to miss even with next-generation genomic sequencing.

21 Aug 2014

Scientists explore chili pepper's effect to develop new drug candidate for pain

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many kinds of pain, which can be caused by inflammation or other problems.

21 Aug 2014

EGFR biomarkers predict NSCLC response to vandetanib

Biomarker analyses of tumour samples from the ZODIAC study indicate that epidermal growth factor receptor gene copy number and mutation status may help identify the non-small-cell lung cancer patients most likely to benefit from treatment with vandetanib plus docetaxel.

20 Aug 2014

Choroidal consequences differ between anti-VEGF therapies

Aflibercept’s possession of a fragment crystallisable region may make it more likely to induce unwanted effects in retinal and choroidal vessels than other anti-vascular endothelial growth factor therapies, say researchers.

20 Aug 2014

CD157 important in malignant pleural mesothelioma

CD157 plays a pivotal role in the progression of malignant pleural mesothelioma and may be useful in the stratification of patients into different prognostic groups, Italian research suggests.

20 Aug 2014

Glenmark announces discovery and initiation of IND enabling studies of innovative bispecific antibody

Glenmark Pharmaceuticals S.A. (GPSA), a wholly owned subsidiary of Glenmark Pharmaceuticals Limited India (GPL), announces the discovery and initiation of IND enabling studies of a novel clinical development candidate, GBR 1302, a HER2xCD3 bispecific antibody.

20 Aug 2014

New antibodies could pave way for more effective drugs to combat influenza infection

Research toward developing new antibodies at the Hebrew University of Jerusalem's Faculty of Medicine could pave the way for more effective drugs to combat influenza infection.

20 Aug 2014

Chemical engineers devise new implantable tissue scaffold coated with bone growth factors

MIT chemical engineers have devised a new implantable tissue scaffold coated with bone growth factors that are released slowly over a few weeks. When applied to bone injuries or defects, this coated scaffold induces the body to rapidly form new bone that looks and behaves just like the original tissue.

20 Aug 2014

Scientists identify biomarker strongly associated with aggressive breast cancer

Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy. The biomarker, a protein called STAT3, provides a smart target for new therapeutics designed to treat this often deadly cancer.

20 Aug 2014

Research finds stronger weapon against leprosy and tuberculosis

In many parts of the world, leprosy and tuberculosis live side-by-side. Worldwide there are approximately 233,000 new cases of leprosy per year, with nearly all of them occurring where tuberculosis is endemic.

20 Aug 2014

Dasatinib: Leukemia drug shows promise for treating skin, breast and other cancers

A leukemia drug called dasatinib shows promise for treating skin, breast and several other cancers, according to researchers at Loyola University Chicago Stritch School of Medicine.

20 Aug 2014

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research led by the Vall d'Hebron Institute of Oncology (VHIO) evidence the most conclusive preclinical results to-date validating Myc inhibition as a therapeutic strategy in glioma - a highly agressive tumor type that notoriously outsmarts current anti-cancer therapies.

19 Aug 2014

Research shows long non-coding RNAs regulate circadian clocks

Researchers at UT Southwestern Medical Center have found a new way that internal body clocks are regulated by a type of molecule known as long non-coding RNA.

19 Aug 2014

Rettsyndrome.Org awards $1.5M to advance translational research, support Neuro-Habilitation Program

The International Rett Syndrome Foundation now doing business as Rettsyndrome.org announces today that the Board of Trustees has awarded $1.5M to support 10 new grants to further translational research and launch of the neuro-habilitation therapeutic program, and fund clinical research.

19 Aug 2014

Researchers identify microRNAs that differentiate male and female fruit flies

Men and women differ in plenty of obvious ways, and scientists have long known that genetic differences buried deep within our DNA underlie these distinctions. In the past, most research has focused on understanding how the genes that encode proteins act as sex determinants.

19 Aug 2014

University of Kansas researcher earns grant to study role of dietary supplement in muscle growth

A University of Kansas professor has been chosen to take part in a grant project that will test the role of a dietary supplement in muscle growth for everyone from athletes to the elderly and has also been named educator of the year by the granting agency.

19 Aug 2014

Natural killer cells can be used to combat acute lymphoblastic leukemia

Researchers at Children's Hospital Los Angeles have shown that a select team of immune-system cells from patients with leukemia can be multiplied in the lab, creating an army of natural killer cells that can be used to destroy the cancer cells.

19 Aug 2014

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Neurotrope, Inc. (OTCQB: NTRP) today announced that results from a new study, entitled, "PKCe Deficits in Alzheimer's Disease Brains and Skin Fibroblasts," published in the recent edition of the peer-reviewed Journal of Alzheimer's Disease and co-authored by Tapan K. Khan, Ph.D.; Abhik Sen, Ph.D.; Jarin Hongpaisan, Ph.D.; Chol S. Lim, Ph.D.; Thomas J. Nelson, Ph.D., and; Dr. Daniel L. Alkon, each of the Blanchette Rockefeller Neurosciences Institute (BRNI), provide further indication of the role that protein kinase C epsilon (PKCe) may play in the potential treatment of Alzheimer's disease (AD).

19 Aug 2014

Research findings call for clinical testing of relevant drugs to prevent NASH

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

19 Aug 2014

Protein News and Research

Further Reading

Shuganjieyu capsule effectively reverses depressive by increasing neurotrophic factor

Deep sequencing technique opens up new possibilities for finding genetic causes for brain disorder

Scientists explore chili pepper's effect to develop new drug candidate for pain

EGFR biomarkers predict NSCLC response to vandetanib

Choroidal consequences differ between anti-VEGF therapies

CD157 important in malignant pleural mesothelioma

Glenmark announces discovery and initiation of IND enabling studies of innovative bispecific antibody

New antibodies could pave way for more effective drugs to combat influenza infection

Chemical engineers devise new implantable tissue scaffold coated with bone growth factors

Scientists identify biomarker strongly associated with aggressive breast cancer

Research finds stronger weapon against leprosy and tuberculosis

Dasatinib: Leukemia drug shows promise for treating skin, breast and other cancers

Research validates Myc inhibition as effective therapeutic strategy for glioma

Research shows long non-coding RNAs regulate circadian clocks

Rettsyndrome.Org awards $1.5M to advance translational research, support Neuro-Habilitation Program

Researchers identify microRNAs that differentiate male and female fruit flies

University of Kansas researcher earns grant to study role of dietary supplement in muscle growth

Natural killer cells can be used to combat acute lymphoblastic leukemia

Study shows bryostatin plays key role in slowing or reversing Alzheimer's disease

Research findings call for clinical testing of relevant drugs to prevent NASH

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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