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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

26 Jul 2024

New study links beans to improved diets in children

New research showing the association between greater pulse consumption and significant health-related outcomes in American children will be presented during the Society for Nutrition Education and Behavior's (SNEB) International Conference 2024 in Knoxville, TN.

26 Jul 2024

Study reveals enhanced electron transport in folded peptides

What puts the electronic pep in peptides? A folded structure, according to a new study in the Proceedings of the National Academy of Sciences.

26 Jul 2024

Researchers identify a potential therapeutic target for advanced multiple sclerosis

Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.

25 Jul 2024

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Researchers created a detailed transcriptomic atlas of six brain regions, revealing cell-type-specific and region-specific vulnerabilities in Alzheimer's disease and highlighting astrocyte genes linked to cognitive resilience.

25 Jul 2024

Can cutting back on extra virgin olive oil make your heart healthier?

Two levels of extra virgin olive oil intake in a plant-based diet both reduce LDL cholesterol, with lower intake showing a more significant effect.

25 Jul 2024

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

In a rigorous medical records study covering tens of thousands of patients, Johns Hopkins Medicine researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.

25 Jul 2024

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego -; a discovery that could lead to therapies for patients with other neurological conditions.

25 Jul 2024

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research-;live, human muscle cells grown on scaffolds fixed on tiny chips-;lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

New insights into how genetic variants influence disease risk

A new study by scientists at deCODE Genetics, a subsidiary of Amgen, shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to various diseases and other human traits.

25 Jul 2024

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Comprehensive analysis of Alzheimer’s brain tissue identifies novel biomarkers

From studying the human genome, to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin dementia. But there's a catch: While new technologies are revealing myriad avenues for Alzheimer's research, it's impossible to know in advance which research pathways will lead to effective treatments.

25 Jul 2024

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of various cancers.

25 Jul 2024

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

24 Jul 2024

WashU study reveals key mechanisms of biological clocks

In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Breakthrough in acute myeloid leukemia treatment targets stem cells

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment.

24 Jul 2024

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Protein News and Research

Further Reading

Overcoming cancer relapse with CAR-Enhancer therapy

New study links beans to improved diets in children

Study reveals enhanced electron transport in folded peptides

Researchers identify a potential therapeutic target for advanced multiple sclerosis

New brain atlas reveals hidden cell vulnerabilities in Alzheimer's

Can cutting back on extra virgin olive oil make your heart healthier?

Study: Iron infusions superior to blood transfusions for surgical patients with anemia

Experimental cancer drug could make thinking easier for individuals with Rett syndrome

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

New insights into how genetic variants influence disease risk

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Comprehensive analysis of Alzheimer’s brain tissue identifies novel biomarkers

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

WashU study reveals key mechanisms of biological clocks

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Breakthrough in acute myeloid leukemia treatment targets stem cells

A guide to advancing biotherapeutic research eBook

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

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