Protein News and Research

RSS

Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

FDA grants Fast Track designation to Akashi Therapeutics' HT-100 for treatment of DMD

Akashi Therapeutics, Inc., announced today that the U.S. Food and Drug Administration has granted Fast Track designation to the company's most advanced product candidate, HT-100 (delayed-release halofuginone), an orally available, small molecule drug candidate intended to reduce fibrosis and inflammation and promote healthy muscle regeneration in boys with DMD.

3 Jul 2014

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

UCB, a global biopharmaceutical leader, and Dermira, Inc., a privately held US-based dermatology company, announced today that they have entered into an exclusive licensing agreement for the development and future commercialization of Cimzia (certolizumab pegol) in dermatology.

3 Jul 2014

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Researchers at the Cleveland Clinic Lou Ruvo Center for Brain Health have conducted the first-ever analysis of clinical trials for Alzheimer's disease (AD), revealing an urgent need to increase the number of agents entering the AD drug development pipeline and progressing successfully towards new therapy treatments.

3 Jul 2014

Researchers identify genetic mutation that may cause parkinsonism in young people

Researchers at the University of Copenhagen and the Copenhagen University Hospital have identified a particular genetic mutation that may cause parkinsonism in young people. The mutation interferes with the brain's transport of the important signal substance dopamine and may also plays a role in mental diseases, e.g. ADHD.

3 Jul 2014

Cyclin D protein activates key tumor suppressor

Researchers at the University of California, San Diego School of Medicine say a protein essential to regulating cell cycle progression - the process of cell division and replication - activates a key tumor suppressor, rather than inactivating it as previously thought.

3 Jul 2014

Researchers discover a way to restore corneal surface

A Boston-based scientific collaborative, led by Harvard Stem Cell Institute researchers, has discovered a way to collect the best cell type for regenerating a damaged cornea-the clear membrane that covers the pupil and directs light into the back of the eye.

3 Jul 2014

NMR Spectroscopy for In-Vitro Diagnostic Research

An interview with Dr. Manfred Spraul, discussing AVANCE, an advanced NMR spectrometer that is being applied to the fields of epidemiology and metabolomics.

From Bruker BioSpin - NMR, EPR and Imaging 2 Jul 2014

Studies show increased risk of pregnancy-induced hypertension in egg donation patients

With an ever-ageing female patient population, egg donation is an increasingly common treatment in infertility. ESHRE's own annual reports on fertility treatments in Europe show a rise in egg donation cycles from 15,028 in 2007 to 24,517 in 2010 (to 4.05% of all treatments). This proportion is still some way behind the USA, where egg donation now accounts for around 12% of all treatments.

2 Jul 2014

Scientists discover 23 new genes linked to heart rhythm

The QT interval is part of the heart's electrical cycle as measured by ECG, and represents the electrical depolarization and repolarization of the ventricles. Lengthened intervals indicate dysfunction in the heart beat and are liable to lead to a five-fold increase in the risk of sudden death from heart failure.

2 Jul 2014

Researchers use simple tactics to reduce unnecessary blood tests, health care spending

Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest pain and to achieve a large decrease in patient charges.

2 Jul 2014

MedImmune initiates MEDI8897 phase I clinical studies for treatment of RSV infections

AIMM Therapeutics, a leading human therapeutic antibody company, today announced that its partner MedImmune, LLC, the global biologics unit of AstraZeneca, has initiated phase I clinical studies with MEDI8897, a best-in-class antibody for the treatment of respiratory syncytial virus (RSV) infections in young, at risk children.

2 Jul 2014

New gene therapy for Acute Intermittent Porphyria

Angeles suffers from a severe and rare genetic disease called Acute Intermittent Porphyria (AIP). This means, one of her genes restrains her liver to produce a specific protein needed for the metabolism of the blood. During an AIP attack Angeles usually feels intense abdominal pain, and her mental status changes. Women live at an increased risk to trigger the symptoms, because porphyria is related to the menstrual cycle.

2 Jul 2014

Research on inflammasomes lays foundations for developing new RA treatments

Patients with more or less severe forms of rheumatoid arthritis (RA) may have the same painful symptoms, but does this mean that the cause of their illness is the same? And therefore that they should all receive the same treatment? Scientists at VIB and Ghent University have demonstrated with their research into inflammasomes that RA should be considered as a syndrome rather than a single disease.

2 Jul 2014

Sugar-coated cells are potentially deadly for cancer patients

Every living cell's surface has a protein-embedded membrane that's covered in polysaccharide chains - a literal sugar coating. A new study by a Cornell University researcher found this coating is especially thick and pronounced on cancer cells and is a crucial determinant of the cell's survival.

2 Jul 2014

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

In the first genome-wide analysis of postsurgical pain in children, pediatric researchers identified variations in genes that affect a child's need for pain-control drugs. The findings suggest that at some point physicians may calibrate pain-medication dosages according to a child's individual genetic makeup.

2 Jul 2014

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

A genomic analysis of clear cell renal cell carcinoma (ccRCC), the most common form of kidney cancer, from 72 patients has uncovered 31 genes that are key to development, growth and spread of the cancer, say researchers from Mayo Clinic in Florida.

2 Jul 2014

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma - the most common form of primary brain cancer - will respond to chemotherapy. The findings are published in the July print issue of Oncotarget.

2 Jul 2014

NEI researchers describe functions of gene responsible for anchoring cilia

Researchers at the National Eye Institute (NEI) have described the functions of a gene responsible for anchoring cilia - sensory hair-like extensions present on almost every cell of the body.

2 Jul 2014

Study details brain mechanisms involved with addictive substances

The National Institutes of Health has turned to neuroscientists at the nation's most "Stone Cold Sober" university for help finding ways to treat drug and alcohol addiction.

1 Jul 2014

Extract of Chinese herb thunder god vine suppresses pancreatic cancer cell

A diagnosis of pancreatic cancer—the fourth most common cause of cancer death in the U.S.—can be devastating. Due in part to aggressive cell replication and tumor growth, pancreatic cancer progresses quickly and has a low five-year survival rate (less than 5 percent).

1 Jul 2014

Protein News and Research

Further Reading

FDA grants Fast Track designation to Akashi Therapeutics' HT-100 for treatment of DMD

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

Analysis of clinical trials reveals urgent need to increase Alzheimer's drug development

Researchers identify genetic mutation that may cause parkinsonism in young people

Cyclin D protein activates key tumor suppressor

Researchers discover a way to restore corneal surface

NMR Spectroscopy for In-Vitro Diagnostic Research

Studies show increased risk of pregnancy-induced hypertension in egg donation patients

Scientists discover 23 new genes linked to heart rhythm

Researchers use simple tactics to reduce unnecessary blood tests, health care spending

MedImmune initiates MEDI8897 phase I clinical studies for treatment of RSV infections

New gene therapy for Acute Intermittent Porphyria

Research on inflammasomes lays foundations for developing new RA treatments

Sugar-coated cells are potentially deadly for cancer patients

CHOP study: Children with specific gene variants may require higher doses of pain-control drugs

Mayo Clinic researchers uncover 31 genes key to clear cell renal cell carcinoma

Researchers identify new biomarker that predicts effectiveness of glioblastoma treatment

NEI researchers describe functions of gene responsible for anchoring cilia

Study details brain mechanisms involved with addictive substances

Extract of Chinese herb thunder god vine suppresses pancreatic cancer cell

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest Life Science News