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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Kamada to present Phase 2/3 clinical trial results of AAT to treat alpha-1 antitrypsin deficiency

Kamada Ltd., a plasma-derived protein therapeutics company focused on orphan indications, will announce results from its Phase 2/3 clinical trial of its proprietary inhaled alpha-1 antitrypsin (AAT) to treat alpha-1 antitrypsin deficiency (AATD) in Europe and Canada on Friday, May 16, 2014, at approximately 7:30 a.m. Eastern time.

15 May 2014

Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

A novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis (PVNS), a rare neoplastic joint disorder, according to new phase I data from Memorial Sloan Kettering Cancer Center and other institutions highlighted to media today in advance of the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO), which will take place from May 30 to June 3 in Chicago.

15 May 2014

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

In 2008, researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mutations in two proteins associated with familial Alzheimer's disease (FAD) disrupt the flow of calcium ions within neurons.

15 May 2014

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

Researchers from University Hospitals (UH) Case Medical Center's Seidman Cancer Center will present findings from a study that found the presence of tumor-infiltrating lymphocytes, a type of white blood cell, ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer.

15 May 2014

Scripps Research Institute scientists show AIDS vaccine could work against changeable site on HIV

A vaccine or other therapy directed at a single site on a surface protein of HIV could in principle neutralize nearly all strains of the virus-thanks to the diversity of targets the site presents to the human immune system.

15 May 2014

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Just because you can't see something doesn't mean it's not there. Brain tumors are an extremely serious example of this and are not only difficult to treat-both adult and pediatric patients have a five-year survival rate of only 30 percent-but also have even been difficult to image, which could provide important information for deciding next steps in the treatment process.

15 May 2014

Scientist wins 2014 Maurice Hilleman/Merck Award for developing vaccine against meningococcal disease

Dan Granoff, MD, of UCSF Benioff Children's Hospital Oakland's research arm CHORI, has been named the 2014 Maurice Hilleman/Merck Award Laureate by the American Society for Microbiology (ASM).

15 May 2014

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Zinc supplements reduce diarrhoea and infections in malnourished children

Zinc supplements reduce diarrhoea and other infections in malnourished children, and may prevent death, according to a new study published in The Cochrane Library.

15 May 2014

New technology has potential to make production of biotech medicines simpler

The final step in the production of a biotech medicine is finishing with the correct sugar structure. This step is essential for the efficacy of the medicine, but it also makes the production process very complex and expensive.

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Introduction to Solid State ChIP technology

A new instructional video from Porvair Sciences explains exactly how to conduct a ChIP assay for epigenetic research starting from a confluent monolayer of human cells.

From Chromatrap® - Porvair Sciences Ltd 14 May 2014

Protein Data Bank now contains over 100,000 structures

Spanning the globe from the US, UK, and Japan, the Worldwide Protein Data Bank (wwPDB) organization announces that the Protein Data Bank archive now contains more than 100,000 entries.

14 May 2014

Study links triple-negative breast cancer to ethnicity, independent of socioeconomics

An analysis of a large nationwide dataset finds that regardless of their socioeconomic status, black women were nearly twice as likely as white women to be diagnosed with triple-negative (TN) breast cancer, a subtype that has a poorer prognosis.

14 May 2014

Novozymes Biopharma, ThioLogics to collaborate on drug-albumin conjugation platform

Novozymes Biopharma has entered a new collaboration with UK-based biotechnology company, ThioLogics. The collaboration brings together Novozymes' modified recombinant human albumin (rAlbumin) Veltis technology, with ThioLogics' site-specific next generation maleimide conjugation platform. This allows Novozymes to offer the pharma industry serum stable albumin drug conjugates with enhanced pharmacokinetic and/or targeting capabilities.

14 May 2014

Protein News and Research

Further Reading

Kamada to present Phase 2/3 clinical trial results of AAT to treat alpha-1 antitrypsin deficiency

Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

Scientists find new way to predict response to platinum-based chemotherapy in women with triple-negative breast cancer

Scripps Research Institute scientists show AIDS vaccine could work against changeable site on HIV

SapC-DOPS technology: New way to image glioblastoma multiforme tumors

Scientist wins 2014 Maurice Hilleman/Merck Award for developing vaccine against meningococcal disease

Anti-depressants could slow onset of Alzheimer's disease

Zinc supplements reduce diarrhoea and infections in malnourished children

New technology has potential to make production of biotech medicines simpler

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Introduction to Solid State ChIP technology

Protein Data Bank now contains over 100,000 structures

Study links triple-negative breast cancer to ethnicity, independent of socioeconomics

Novozymes Biopharma, ThioLogics to collaborate on drug-albumin conjugation platform

USC/NYU researchers develop small molecule that interferes with cancer progression with minimal side effects

New study sheds light on why athletes are more likely to have abnormal heart rhythms

Baylor receives $3.3M grant from NIAMS to advance research in autoimmune diseases

Scientists discover novel protein fragments that may protect against Alzheimer's disease

Scientists find new drug that improves effectiveness of radiotherapy in stopping tumor growth

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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