Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Blocking function of enzyme slows spread of pancreatic cancer, say researchers

A research team from Imperial College London has shown that blocking the function of an enzyme known as Hhat slows the growth and spread of pancreatic cancer, by preventing a protein called Hedgehog from stimulating nearby normal cells to help the cancer.

13 Mar 2014

Gene linked with breast cancer susceptibility plays critical role in obesity and diabetes

The gene known to be associated with breast cancer susceptibility, BRCA 1, plays a critical role in the normal metabolic function of skeletal muscle, according to a new study led by University of Maryland School of Public Health researchers.

13 Mar 2014

Scientists discover that natural product in grapefruit can prevent kidney cysts

Scientists at Royal Holloway, University of London, have discovered that a natural product found in grapefruit can prevent kidney cysts from forming.

13 Mar 2014

Protein Metrics releases Byologic software to improve analytical quality

Protein Metrics, Inc., a leading provider of software for rapid and thorough protein characterization, today announced the release of Byologic. Byologic software enables easy and convenient identification and quantification of sequence variants, protein modifications, and degradants down to trace concentrations.

12 Mar 2014

N30 Pharma begins oral dosing in N91115 Phase 1 trial for treatment of cystic fibrosis

N30 Pharmaceuticals, Inc. announced today that it has begun oral dosing of N91115 in a Phase 1 clinical trial. N91115, a novel inhibitor of S-nitrosoglutathione reductase (GSNOR), is being developed for the treatment of cystic fibrosis (CF).

12 Mar 2014

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

A team of researchers from the National Institutes of Health, Emory University and Cedars-Sinai - specialists in identifying and treating very rare diseases - used three innovative tools to detect a previously unknown gene mutation, test potential therapies in the lab, and initiate personalized drug treatment for a boy with a lifelong history of uncontrollable seizures that caused significant impact on his cognitive and social development.

12 Mar 2014

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge.

12 Mar 2014

Asian Diabetes Prevention Initiative website aims to put stop to type2 diabetes in Asia

The rapidly emerging diabetes epidemic in Asia has the potential to overwhelm health care systems, undermine economic growth, and inflict unprecedented levels of disability on the world's most populous continent.

12 Mar 2014

Parkinson disease patients with higher CSF experience faster cognitive decline

Counterintuitive Findings Offer New Insights into Parkinson Disease Pathology, According to New Research Published in The American Journal of Pathology

12 Mar 2014

High animal protein diet may reduce functional decline in older adults

A diet high in protein, particularly animal protein, may help elderly individuals function at higher levels physically, psychologically, and socially, according to a study published in the Journal of the American Geriatrics Society.

12 Mar 2014

MIT biologists discover how cancer cells make their escape

About 90 percent of cancer deaths are caused by tumors that have spread from their original locations. This process, known as metastasis, requires cancer cells to break loose from their neighbors and from the supportive scaffold that gives tissues their structure.

11 Mar 2014

CT scans predict effectiveness of chemotherapy for pancreatic cancer

Computed tomography (CT) scans routinely taken to guide the treatment of pancreatic cancer may provide an important secondary benefit. According to new research from The University of Texas MD Anderson Cancer Center, the scans also reflect how well chemotherapy will penetrate the tumor, predicting the effectiveness of treatment.

11 Mar 2014

Monash University research offers new hope to people with heart attacks

Melbourne scientists are a step closer to creating a new drug to stop a heart attack in its tracks and reduce the damage caused, without any side effects.

11 Mar 2014

Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Synta Pharmaceuticals Corp. and QuantumLeap Healthcare Collaborative today announced that Synta's lead drug candidate, the Hsp90 inhibitor ganetespib, has been selected for study in the I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2).

11 Mar 2014

Researchers investigate stickiness of leukaemia cells and its link to drug resistance

Researchers in Manchester have investigated the stickiness of leukaemia cells, and whether this is linked to drug resistance.

11 Mar 2014

Aged mice lacking antioxidant protein Nrf2 show poor stem cell regeneration

Good news for lifelong exercisers: Along with its salutary effects on the heart, weight, and other facets of health, physical activity also helps to regenerate muscle mass, which tends to diminish as people age.

11 Mar 2014

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Aeras today announced the initiation of the first randomized, controlled tuberculosis (TB) vaccine trial designed to study prevention of Mycobacterium tuberculosis (Mtb) infection by vaccination.

11 Mar 2014

Pretreatment with SSTF prevents cerebral ischemia-reperfusion injury, says study

Focal cerebral ischemia-reperfusion may lead to neuronal loss in the hippocampus, which is regarded as one of the basic pathological mechanisms underlying cognitive impairment.

11 Mar 2014

Penn researchers use mathematical modeling to better understand mechanisms in TBI

Even the mildest form of a traumatic brain injury, better known as a concussion, can deal permanent, irreparable damage. Now, an interdisciplinary team of researchers at the University of Pennsylvania is using mathematical modeling to better understand the mechanisms at play in this kind of injury, with an eye toward protecting the brain from its long-term consequences.

11 Mar 2014

Glycoprofiling test could halve number of false-positives in diagnosis of ovarian cancer

The world's most widespread test for ovarian cancer reports false-positives in 94 of 100 diagnosed cases. Now, chemists at the University of Copenhagen working with clinical researchers at University College London have developed a method able to halve the number of false-positives.

11 Mar 2014

Protein News and Research

Further Reading

Blocking function of enzyme slows spread of pancreatic cancer, say researchers

Gene linked with breast cancer susceptibility plays critical role in obesity and diabetes

Scientists discover that natural product in grapefruit can prevent kidney cysts

Protein Metrics releases Byologic software to improve analytical quality

N30 Pharma begins oral dosing in N91115 Phase 1 trial for treatment of cystic fibrosis

Three innovative tools to detect, test and initiate personalized drug treatment for seizures

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

Asian Diabetes Prevention Initiative website aims to put stop to type2 diabetes in Asia

Parkinson disease patients with higher CSF experience faster cognitive decline

High animal protein diet may reduce functional decline in older adults

MIT biologists discover how cancer cells make their escape

CT scans predict effectiveness of chemotherapy for pancreatic cancer

Monash University research offers new hope to people with heart attacks

Synta Pharmaceuticals' Hsp90 inhibitor ganetespib selected for study in I-SPY 2 TRIAL

Researchers investigate stickiness of leukaemia cells and its link to drug resistance

Aged mice lacking antioxidant protein Nrf2 show poor stem cell regeneration

Controlled TB vaccine trial designed to study prevention of Mtb infection by vaccination

Pretreatment with SSTF prevents cerebral ischemia-reperfusion injury, says study

Penn researchers use mathematical modeling to better understand mechanisms in TBI

Glycoprofiling test could halve number of false-positives in diagnosis of ovarian cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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