Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex to target with a drug since it is also crucial to the healthy functioning of many immune cells in the body, not just B cells gone bad.

4 Mar 2013

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers supported by The ALS Association have discovered how mutations in new amyotrophic lateral sclerosis (ALS) genes cause not only ALS but also other diseases of the brain, muscle and bone.

4 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

4 Mar 2013

Study identifies two gene mutations that lead to death of nerve cells in ALS

A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

4 Mar 2013

Simple tips can make lunchtime healthier for the body, mind and bank account

Lunch hour spent in a restaurant can be a good break, but it comes with drawbacks. Finance and nutrition sciences experts at the University of Alabama at Birmingham (UAB) say dining out during the work day too often can be an expensive and unhealthy habit, but simple tips can make lunchtime healthier for the body, mind and bank account.

3 Mar 2013

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS).

3 Mar 2013

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.

3 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature.

2 Mar 2013

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.

2 Mar 2013

Kallikrein gene variants modulate OSCC development

Polymorphisms in the kallikrein7 and kallikrein10 genes are associated with the development and progression of oral squamous cell carcinoma, a study in Taiwanese men indicates.

1 Mar 2013

Eye-rubbing may provoke, aggravate keratoconus

Rubbing the eyes leads to an increase in protease activity and levels of protease and inflammatory mediators, a clinical study shows.

1 Mar 2013

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants.

1 Mar 2013

Wright Medical Group acquires BioMimetic Therapeutics

Wright Medical Group, Inc. today announced that it has completed its acquisition of BioMimetic Therapeutics, Inc. The transaction combines BioMimetic's breakthrough biologics platform and pipeline with Wright's established sales force and product portfolio, to further accelerate growth opportunities in Wright's Extremities business.

1 Mar 2013

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

Griffith University's Institute for Glycomics has launched human trials for a vaccine against Streptococcus A, the germ that causes rheumatic fever.

1 Mar 2013

UPV/EHU team uses lipid nanoparticles to develop new formulations for drug delivery

At the Faculty of Pharmacy of the Basque Public University (UPV/EHU) the Pharmacokinetics, Nanotechnology and Gene Therapy research team is using nanotechnology to develop new formulations that can be applied to drugs and gene therapy.

1 Mar 2013

IDF welcomes FAO recommendations on dietary protein quality evaluation in human nutrition

As the global population continues to rise, there is increasing pressure to provide adequate quantities of safe, nutritious food products in a sustainable manner. As part of its commitment to address this challenge, the International Dairy Federation (IDF) welcomes the recommendations of the report by the Food and Agriculture Organization of the United Nations (FAO) on dietary protein quality evaluation in human nutrition.

28 Feb 2013

Protein News and Research

Further Reading

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Researchers discover new candidate disease proteins for neurodegenerative disorders

Study finds how to shut down Bcl6 in diffuse large B-cell lymphoma

Study identifies how new ALS gene mutations cause other diseases of the brain, muscle and bone

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Study identifies two gene mutations that lead to death of nerve cells in ALS

Simple tips can make lunchtime healthier for the body, mind and bank account

Shortage of TDP-43 protein causes muscle wasting and stunted nerve cells

Knockdown or deletion of Jmjd3 gene could improve efficiency of stem cell conversion process

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Researchers identify novel signaling pathway responsible for neuroprotective activity of parkin

Kallikrein gene variants modulate OSCC development

Eye-rubbing may provoke, aggravate keratoconus

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

Wright Medical Group acquires BioMimetic Therapeutics

Griffith University's Institute for Glycomics launches human trials for Streptococcus A vaccine

UPV/EHU team uses lipid nanoparticles to develop new formulations for drug delivery

IDF welcomes FAO recommendations on dietary protein quality evaluation in human nutrition

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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