Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Multi-institutional research uncovers new mechanism for treatment of lung cancer

A multi-institutional research study has uncovered a new mechanism that may lead to unique treatments for lung cancer, one of the leading causes of death worldwide.

18 Jun 2012

A novel candidate gene in human early-onset degenerative ataxias

Researchers at the University of Helsinki and the Folkh-lsan Research Center, Finland, have identified the genetic cause of early-onset progressive cerebellar degeneration the Finnish Hound dog breed. The study, led by Professor Hannes Lohi, revealed a new disease mechanism in cerebellar degeneration. A mutation was identified in the SEL1L gene, which has no previous link to inherited cerebellar ataxias.

18 Jun 2012

Infinity voluntarily stops saridegib Phase 2 trial for chondrosarcoma

Infinity Pharmaceuticals, Inc. today announced interim data from its Phase 2, double-blind, randomized, placebo-controlled study of saridegib (IPI-926) in patients with metastatic or locally advanced, inoperable chondrosarcoma. The primary endpoint of the Phase 2 study was progression-free survival.

18 Jun 2012

Illumina's new patent infringement suit targets Complete Genomics' cPal read technology

Illumina (NASDAQ:ILMN) announced today that the company has filed an additional patent infringement suit against Complete Genomics, Inc. Illumina is seeking all available remedies, including injunctive relief.

From Illumina, Inc. 18 Jun 2012

CMC Biologics' Bothell manufacturing and testing facilities receive cGMP compliance

CMC Biologics, a leading contract manufacturing organization (CMO) known for its technical excellence in process development and cGMP manufacture, has received a Certificate of Good Manufacturing Practice (GMP) Compliance for commercial manufacturing issued by the Medicines and Healthcare products Regulatory Agency (MHRA).

18 Jun 2012

Ambrx, Merck collaborate to develop and commercialize biotherapeutic drug conjugates

Ambrx today announced that the company has entered into a collaboration with Merck to design and develop rationally optimized biologic drug conjugates based on Ambrx's site-specific protein medicinal chemistry technology.

18 Jun 2012

Is curry good for you?

There have been several news stories over the years reporting that curry may be good for us. Most of them refer to a chemical in curry, known as curcumin.

18 Jun 2012

Updated data from ARIAD’s ponatinib pivotal trial on CML or Ph+ ALL

ARIAD Pharmaceuticals, Inc. today announced updated clinical data from the pivotal PACE trial of its investigational pan-BCR-ABL inhibitor, ponatinib, in patients with chronic myeloid leukaemia (CML) or Philadelphia-positive acute lymphoblastic leukaemia (Ph+ ALL), who are resistant or intolerant to dasatinib or nilotinib or who have the T315I mutation.

18 Jun 2012

Scientists discover master regulator gene needed for development of M cells

Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.

18 Jun 2012

Patients with NK/T-cell lymphomas might benefit from treatment with JAK inhibitors

A substantial proportion of NK/T-cell lymphomas harbor Janus Kinase 3 gene mutations. Patients with these lymphomas might benefit from treatment with a Janus Kinase inhibitor according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

16 Jun 2012

New approach to drug design may yield more effective and less toxic cancer medicines

A new approach to drug design, pioneered by a group of researchers at the University of California, San Francisco (UCSF) and Mt. Sinai, New York, promises to help identify future drugs to fight cancer and other diseases that will be more effective and have fewer side effects.

16 Jun 2012

Immune system may play a key role in removing Alzheimer's protein

Recent work in mice suggested that the immune system is involved in removing beta-amyloid, the main Alzheimer's-causing substance in the brain. Researchers have now shown for the first time that this may apply in humans.

16 Jun 2012

NextGen commercializes new assay for identification of biomarkers in brain disorders

NextGen Group Plc, the AIM listed company developing its own diagnostics product pipeline and providing diagnostic biomarker development services, announces the commercialisation of a new assay for the identification of diagnostic biomarkers in brain disorders in animal models.

15 Jun 2012

New spin to understanding of relationship between Alzheimer's disease and diabetes

A new spin to our understanding of the relationship between Alzheimer's disease and diabetes, which could point to a therapeutic target for both diseases, is published in a research report in the June 2012 issue of the journal Genetics.

15 Jun 2012

Exercise-related hormones do not play an influential role in building muscle

New research from scientists at McMaster University reveals exercise-related testosterone and growth hormone do not play an influential role in building muscle after weightlifting, despite conventional wisdom suggesting otherwise.

15 Jun 2012

First U.S. population prevalence study of mutations in the gene that causes fragile X

The first U.S. population prevalence study of mutations in the gene that causes fragile X syndrome, the most common inherited form of intellectual disability, suggests the mutation in the gene - and its associated health risks - may be more common than previously believed.

15 Jun 2012

Transplantation of tissue-engineered vein is a success and offers hope for patients who lack suitable veins for dialysis or bypass surgery

The first biologically tissue-engineered vein grown from a patient’s own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her quality of life.

15 Jun 2012

SQI raises CDN $754,000 in third and final tranche of private placement

SQI Diagnostics Inc., a life sciences company that develops and commercializes proprietary technologies and products for advanced microarray diagnostics, announced today it has raised gross proceeds of CDN $754,000 from the closing of the third and final tranche of a non-brokered private placement of 430,713 units priced at $1.75 per Unit.

15 Jun 2012

Digoxin can protect against high blood pressure and heart failure

An ancient heart drug that's inspired the work of herbalists and poets for centuries may treat a condition that plagues millions of overstressed and overweight Americans today.

15 Jun 2012

AMPK enzyme promotes survival of cancer cells: Research

A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of Illinois at Chicago College of Medicine have found.

15 Jun 2012

Protein News and Research

Further Reading

Multi-institutional research uncovers new mechanism for treatment of lung cancer

A novel candidate gene in human early-onset degenerative ataxias

Infinity voluntarily stops saridegib Phase 2 trial for chondrosarcoma

Illumina's new patent infringement suit targets Complete Genomics' cPal read technology

CMC Biologics' Bothell manufacturing and testing facilities receive cGMP compliance

Ambrx, Merck collaborate to develop and commercialize biotherapeutic drug conjugates

Is curry good for you?

Updated data from ARIAD’s ponatinib pivotal trial on CML or Ph+ ALL

Scientists discover master regulator gene needed for development of M cells

Patients with NK/T-cell lymphomas might benefit from treatment with JAK inhibitors

New approach to drug design may yield more effective and less toxic cancer medicines

Immune system may play a key role in removing Alzheimer's protein

NextGen commercializes new assay for identification of biomarkers in brain disorders

New spin to understanding of relationship between Alzheimer's disease and diabetes

Exercise-related hormones do not play an influential role in building muscle

First U.S. population prevalence study of mutations in the gene that causes fragile X

Transplantation of tissue-engineered vein is a success and offers hope for patients who lack suitable veins for dialysis or bypass surgery

SQI raises CDN $754,000 in third and final tranche of private placement

Digoxin can protect against high blood pressure and heart failure

AMPK enzyme promotes survival of cancer cells: Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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