Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Yeast-based vaccine induces immune responses and reduces tumor size in mice

Scientists have found that vaccination with a heat-killed, non-toxic yeast that is genetically engineered to manufacture a common tumor protein can induce specific and repeated anti-tumor immune responses in mice.

1 Jul 2008

New clues to the biological basis of migraines

Fifteen percent to 20 percent of people worldwide suffer from migraines - excruciating headaches often presaged by dramatic sensations, or "auras." By studying a rare, inherited form of migraine, researchers at Vanderbilt University Medical Center have found clues to the biological basis of the painful, debilitating disorder.

1 Jul 2008

Cancer cells revert to normal at specific signal threshold

Cancer starts when key cellular signals run amok, driving uncontrolled cell growth. But scientists at the Stanford University School of Medicine report that lowering levels of one cancer signal under a specific threshold reverses this process in mice, returning tumor cells to their normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing side effects for the body's healthy cells.

1 Jul 2008

Carbohydrate and caffeine following exhaustive exercise helps muscles refuel

Recipe to recover more quickly from exercise: Finish workout, eat pasta, and wash down with five or six cups of strong coffee.

1 Jul 2008

Low levels of good cholesterol could signal dementia

A study by British and French scientists has revealed that the risk of dementia may increase with a lack of "good" cholesterol in middle age.

1 Jul 2008

Low levels of high-density lipoproteins linked to memory loss, dementia risk

Low levels of high-density lipoproteins (HDL) - the "good" cholesterol - in middle age may increase the risk of memory loss and lead to dementia later in life, researchers reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

30 Jun 2008

Scientists fortify the cassava plant - a day's nutrition in a single meal

Scientists have determined how to fortify the cassava plant, a staple root crop in many developing countries, with enough vitamins, minerals and protein to provide the poor and malnourished with a day's worth of nutrition in a single meal.

30 Jun 2008

Neural stem cell development may be linked to Autism

In a breakthrough scientific study published today in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism.

30 Jun 2008

Hypertension, insulin resistance and immune suppression links

Many of the 75 million Americans with essential hypertension also develop diabetes and other complications in addition to their high blood pressure, and researchers have discovered a common molecular mechanism in a strain of rat that explains why such metabolic disorders arise together in mammals.

30 Jun 2008

Zinc finger technology brings personalized HIV therapy a step closer

Researchers at the University of Pennsylvania School of Medicine and collaborators are using minute, naturally occurring proteins called zinc fingers to engineer T cells to one day treat AIDS in humans.

30 Jun 2008

Dividing cells find their middle by following a protein contour map

Self-organization keeps schools of fish, flocks of birds and colonies of termites in sync. It's also, according to new research, the way cells regulate the final stage of cell division. Scientists at Rockefeller University have shown that a protein-chemistry-based contour map, which helps individual proteins locate the center of their cell without direction from a 'master organizer,' is key to ensuring accurate division during mitosis.

30 Jun 2008

Molecular movies reveal dynamic lives of proteins

Capturing moving images of tiny protein molecules is the aim of a new research project announced today at Imperial College London. The research will reveal, on extremely short timescales, the miniscule movements of proteins which help carry out important biological processes in people, animals, insects and plants.

30 Jun 2008

Growth hormone FGF21's link to starvation may be clue to increasing life span, researchers find

Researchers at UT Southwestern Medical Center have determined that starvation blocks the effects of growth hormone via a mechanism that may have implications in treating diabetes and extending life span.

30 Jun 2008

Growth-stimulating molecule called p110beta a promising cancer drug target in prostate tumors

Scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a "powerhouse" that drives runaway cell growth.

27 Jun 2008

Protein Ronin shown to be an alternate control for embryonic stem cells

Like the masterless samurai for whom it is named, the protein Ronin chooses an independent path, maintaining embryonic stem cells in their undifferentiated state and playing essential roles in genesis of embryos and their development, said Baylor College of Medicine researchers who reported on this novel cellular regulator in the current issue of the journal Cell.

27 Jun 2008

Unique pheromone detection system uncovered by researchers

Researchers at UT Southwestern Medical Center have overturned the current theory of how a pheromone works at the molecular level to trigger behavior in fruit flies.

26 Jun 2008

Discovery of toxic key to Alzheimer’s disease memory loss

Using new scientific techniques, scientists have unlocked the cascade of molecular events that lead to Alzheimer's disease.

26 Jun 2008

Aventix Pharma takes over key patents for innovative screening tool for treatments for cystic fibrosis

The rights to key patents for an innovative screening tool for treatments for cystic fibrosis were transferred today to Swiss biotech company Axentis Pharma AG.

26 Jun 2008

Pregnancy may protect against bladder cancer

Female mice that had never become pregnant had approximately 15 times as much cancer in their bladders as their counterparts that had become pregnant, according to new findings by investigators at the University of Rochester Medical Center. Their work appears online as a rapid communication in the journal Urology.

26 Jun 2008

Discovery of second genetic risk factor for developing late-onset Alzheimer's disease

Researchers have discovered the second, strong genetic risk factor for developing late-onset Alzheimer's disease, according to a new report in the June 27th issue of the journal Cell, a Cell Press publication.

25 Jun 2008