Protein Synthesis News and Research

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Good news for treating children with amblyopia

New research findings led by Thomas Krahe and Ary S. Ramoa of Virginia Commonwealth University School of Medicine offer two pieces of good news for treating children with amblyopia.

19 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

First genetic evidence that protein synthesis is critical for the regulation of memory formation

A group of Montreal researchers has discovered that GCN2, a protein in cells that inhibits the conversion of new information into long-term memory, may be a master regulator of the switch from short-term to long-term memory.

29 Aug 2005

Calcium fights prostate cancer

Calcium, more familiar in its role as one of the building blocks of the body, is being enlisted as a tool in the fight against prostate cancer.

15 Aug 2005

Primordial soup where life began on earth was hot and not cold

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe.

2 Aug 2005

Light used to regulate protein synthesis

Proteins are the puzzle-pieces of life, involved in how organisms grow and flourish, but studying their complex biological processes in living systems has been extremely difficult.

27 Jun 2005

Study challenges understanding of how messenger RNAs are translated into proteins

Our understanding of how messenger RNAs are translated into proteins is challenged by a new study published in the Open Access journal Journal of Biology.

27 Jun 2005

Researchers discover how microRNA are involved in the development of heart muscle

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.

12 Jun 2005

Research provides new insight into how individual genes control regeneration

Although they may look small and unassuming, planarian worms are famous in the scientific world for their extraordinary ability to regenerate body parts after injury. Even a small piece cut off a planarian can reorganize and regenerate to form a whole new worm.

2 May 2005

Pattern of gene expression predicts multiple drug resistance, treatment failure in pediatric leukemia

The discovery of a specific pattern of gene expression linked to multiple-drug resistance of leukemic cells is giving researchers crucial information into why standard therapies fail to cure some children with acute lymphoblastic leukemia (ALL). This finding, from investigators at St. Jude Children’s Research Hospital, could lead to development of drugs that would overcome that resistance.

24 Apr 2005

Using X-ray crystallography, researchers have "seen" the structural basis for antibiotic resistanc

Using X-ray crystallography, researchers at Yale have "seen" the structural basis for antibiotic resistance to common pathogenic bacteria, facilitating design of a new class of antibiotic drugs, according to an article in Cell.

22 Apr 2005

Gene expression pattern predicts multiple drug resistance

St. Jude Children's Research Hospital discovery of genetic links to multi-drug resistance gives clinicians new insight into the cause of treatment failure and suggests targets for novel anti-leukemic drugs

19 Apr 2005

Alcoholism reduces male heart muscle’s ability to synthesize protein

The fact that men and women react differently to alcohol consumption and addiction, health and behavior risks, disease and death is well known and accepted. Women get drunker faster on less alcohol than men, but fewer women drink either occasionally or heavily, and men are more likely to become dependent on alcohol.

3 Apr 2005

Study reveals how brain's immune system fights viral encephalitis

The findings, published as the cover study in the latest issue of Virology, show that proteins in neurons fight the virus at multiple stages - by preventing the formation of viral RNA and proteins, and blocking the virus' release, which could infect other cells in the brain.

16 Mar 2005

How do you remember your own name?

How do you remember your own name? Is it possible ever to forget it? The memory trace, or engram, "feels" like it is stored permanently in the brain and it will never be forgotten.

16 Jan 2005

Gene decoding revealed at atomic level

A recent finding by a North Carolina State University biochemist advances the fundamental biology of how genetic information, encoded in DNA, is decoded for the production of proteins.

4 Dec 2004

A single change in a person’s DNA can contribute to a range of life-shortening risk factors

A woman with hypertension, low magnesium levels, and a cooperative family allowed scientists to pinpoint the mutation, which affects the genes of the mitochondria — the energy-producing power plants of the cell that are passed from mother to offspring.

25 Oct 2004

Single protein appears central to the formation of the long-term memories

Researchers at the National Institute of Child Health and Human Development have discovered that a single protein appears central to the formation of the long-term memories.

16 Oct 2004