Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

The first proteomic analysis of an animal model of a rare, sometimes deadly birth defect, Smith-Lemli-Opitz Syndrome (SLOS), has revealed that the molecular mechanisms that cause it are more complex than previously understood.

12 Sep 2013

Expression of stress protein induced by ischemia/reperfusion injury, say researchers

Spinal cord ischemia/reperfusion injury is a stress injury to the spinal cord. Therefore, research on the expression of stress-related protein in neurons could be of great significance for the pathological mechanism and control measures for spinal cord ischemia/reperfusion injury.

11 Sep 2013

Rutgers scientist finds important clue on origins of multiple sclerosis

The search for the cause of multiple sclerosis, a debilitating disease that affects up to a half million people in the United States, has confounded researchers and medical professionals for generations. But Steven Schutzer, a physician and scientist at Rutgers New Jersey Medical School, has now found an important clue why progress has been slow - it appears that most research on the origins of MS has focused on the wrong part of the brain.

11 Sep 2013

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.

11 Sep 2013

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Weill Cornell Medical College announced today that it has received a $100 million gift from longtime benefactors Joan and Sanford I. Weill and the Weill Family Foundation to launch the Medical College's $300 million Driving Discoveries, Changing Lives campaign dedicated to using the most advanced scientific approaches to rapidly translate research breakthroughs into innovative treatments and therapies for patients.

10 Sep 2013

Nanofibrous nerve conduits for repair of long sciatic nerve defects

Autografts or allografts are commonly used in the repair of damaged peripheral nerves. However, similar problems have been encountered in allografting or xenografting. Previous studies concerning artificial neural tubes to repair nerve defects mainly focus on peripheral nerve defects less than 30 mm.

5 Sep 2013

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Researchers from The University of Manchester and Central Manchester University Hospitals NHS Trust have identified proteins in the blood that could be used to predict whether a woman in her first pregnancy is at increased risk of developing pre-eclampsia.

From The University of Manchester 4 Sep 2013

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

3 Sep 2013

Study: Mosquitoes able to smell major human host odorants better at night

In work published this week in Nature: Scientific Reports, a team of researchers from the University of Notre Dame's Eck Institute for Global Health, led by Associate Professor Giles Duffield and Assistant Professor Zain Syed of the Department of Biological Sciences, revealed that the major malaria vector in Africa, the Anopheles gambiae mosquito, is able to smell major human host odorants better at night.

31 Aug 2013

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine.

29 Aug 2013

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

Joslin scientists, in collaboration with researchers from the Harvard School of Public Health and Italian research institutes, have identified a previously unknown genetic variant associated with an increased risk of coronary heart disease (CHD) in type 2 diabetic patients.

28 Aug 2013

2ml deep well plate launched by Porvair Sciences

Porvair Sciences has developed the first 96-well round deep well plate that genuinely delivers 2.00 ml liquid capacity / well in an automation compatible SLAS / ANSI footprint. The revolutionary "common wall" design provides a full 2ml round well, round bottom well within a 45mm height limit, thus ensuring full compatibility with most plate handling equipment.

From Porvair Sciences Limited 27 Aug 2013

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have demonstrated for the first time the selective cytotoxicity of Bacillus thuringiensis subsp. israelensis Cry4B toxin is mediated by BT-R3.

27 Aug 2013

New proteins help patients to get more accurate diagnosis of MS

A group of proteins identified by researchers at Stockholm's KTH Royal Institute of Technology could play a role in helping multiple sclerosis patients get more accurate diagnostics about the severity and progress of their disease.

14 Aug 2013

TUM scientists decode typical protein profile of tumor cells

In what is the biggest study of its kind to date, researchers from Technische Universit-t M-nchen have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular proteins," says Prof. Bernhard K-ster, Head of the TUM Chair of Proteomics and Bioanalytics. "Identifying the proteome the protein portfolio of tumor cells increases our chances of finding new targets for drugs."

9 Aug 2013

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

PerFix-Expose1 and PerFix-nc1, innovative new reagent kits for intracellular staining from Beckman Coulter Life Sciences, minimize sample manipulation for a streamlined workflow that delivers high quality results. Developed for use on Beckman Coulter’s Gallios1 and Navios2 series flow cytometers and compatible with all Beckman Coulter Life Sciences’ fluorochromes, the kits enable a clear focus on the cytoplasmic and nuclear compartments of the cell.

8 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure.

1 Aug 2013

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

One major hallmark of cancer cells is their ability to survive under stressful conditions. A new study spearheaded by researchers at Sanford-Burnham Medical Research Institute reveals how a promising anticancer compound called SMIP004 specifically kills prostate cancer cells by compromising their ability to withstand environmental stress.

31 Jul 2013

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

The Society for Free Radical Biology & Medicine recently named the University of Kentucky's Dr. Allan Butterfield as the recipient of its 2013 Discovery Award.

30 Jul 2013

Proteomics News and Research

Further Reading

New technique provides better understanding of factors causing Smith-Lemli-Opitz Syndrome

Expression of stress protein induced by ischemia/reperfusion injury, say researchers

Rutgers scientist finds important clue on origins of multiple sclerosis

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Weill Cornell Medical College gets $100M gift to launch Driving Discoveries, Changing Lives campaign

Nanofibrous nerve conduits for repair of long sciatic nerve defects

Proteins in blood predict women at risk of pre-eclampsia during first pregnancy

Proteins in blood could predict woman at increased risk of developing pre-eclampsia

Study: Mosquitoes able to smell major human host odorants better at night

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Genetic variant linked with increased risk of CHD in type 2 diabetic patients

2ml deep well plate launched by Porvair Sciences

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

New proteins help patients to get more accurate diagnosis of MS

TUM scientists decode typical protein profile of tumor cells

New reagent kits for intracellular staining from Beckman Coulter Life Sciences

New research may influence development of anti-viral therapies to fight against Dengue

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

Researchers reveal how SMIP004 anticancer compound targets prostate cancer cells

Kentucky researcher receives 2013 Discovery Award from Society for Free Radical Biology & Medicine

Omics eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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