Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

CLAMP: A newly discovered protein that regulates genes

They say a good man is hard to find. Were it not for a newly discovered protein, the X chromosome of a male fruit fly could never be found by a gene-regulating complex that male flies need to develop and survive. And that case is just one example of what the new finding means. More generally, the research provides biologists with a model of how proteins that govern gene transcription find their targets on chromosomes, a process that's essential to healthy cell function and sometimes implicated in disease.

22 Jul 2013

Breast cancer pilot study: Patients benefit from treatments guided by molecular profiling

The Side-Out Foundation's breast cancer pilot study, led by the Translational Genomics Research Institute, Translational Drug Development and Scottsdale Healthcare, has shown that cancer patients do better when their treatment is guided by molecular profiling.

18 Jul 2013

Microfuge 20 and 20R microcentrifuges from Beckman Coulter Life Sciences simplify setup, offer increased speed and capacity

Microfuge 20 and 20R microcentrifuges from Beckman Coulter are designed to meet the specific requirements of a wide range of research applications.

From Beckman Coulter Life Sciences - Centrifugation 17 Jul 2013

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

C2N Diagnostics, CIL sign collaborative research and global supplier agreement

C2N Diagnostics today announced that it has signed a collaborative research and a global, exclusive supplier agreement with Cambridge Isotope Laboratories, Inc. The partnership guarantees C2N's future access to mass quantities of highly enriched stable isotopes at predictable prices.

12 Jul 2013

Researchers are one step closer to finding solution for atherosclerosis in diabetic patients

Researchers at Joslin Diabetes Center have discovered that when excessive PKC beta is found in the endothelium, the thin layer of cells that line blood vessels, atherosclerosis is exacerbated. Their findings were published on-line on June 11 by Circulation Research.

11 Jul 2013

Collaborative research yields a wiring map on how TB responds to changes in environment

Despite decades of research on the bacterium that causes tuberculosis (TB), scientists have not had a comprehensive understanding of how the bacterium is wired to adapt to changing conditions in the host.

5 Jul 2013

Salsalate lowers blood glucose and improves glycemic control in T2D, say scientists

Joslin scientists report that salsalate, a drug used to treat arthritis, lowers blood glucose and improves glycemic control in type 2 diabetes. These findings, which were published today by the Annals of Internal Medicine, provide additional evidence that salsalate may be an effective drug to treat type 2 diabetes.

3 Jul 2013

Research suggests new models for study of Barrett's esophagus

Research focused on the regulation of the adult stem cells that line the gastrointestinal tract of Drosophila suggests new models for the study of Barrett's esophagus.

28 Jun 2013

PLK1 crucial for proper functioning of cancer cells, researchers reveal

One of the main indicators for determining the activity of a tumour or cancer is cell division. Cancer cells divide more than other types and the genes and molecules involved in the process of division are, often, targets for identifying and treating certain types of cancer.

26 Jun 2013

VILLUM Foundation grants $10.6 M to the University of Southern Denmark

The University of Southern Denmark (SDU) at Odense has received a VILLUM Foundation grant of Euro 8 M (US$ 10.6 M) to establish a research infrastructure for Bioanalytical Sciences.

19 Jun 2013

SAP and TUM decode human proteome and provide data for biomedical research

As personalized medicine is on the rise, the healthcare field is discovering the opportunities of "big data" analysis. The result of a joint project between the TUM Chair of Proteomics and Bioanalytics, SAP and the SAP Innovation Center, ProteomicsDB, is a major step forward in human proteomics.

12 Jun 2013

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Advanced metastatic melanoma is a disease that has proven difficult to eradicate. Despite the success of melanoma-targeting drugs, tumors inevitably become drug resistant and return, more aggressive than before. In the current issue of the journal Cancer Cell, however, researchers at The Wistar Institute describe how they increase the effectiveness of anti-melanoma drugs by combining anticancer therapies with diabetes drugs.

12 Jun 2013

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Elderly mice suffering from age-related heart disease saw a significant improvement in cardiac function after being treated with the FDA-approved drug rapamycin for just three months.

11 Jun 2013

Sensational proteomics results enabled by Bruker’s new IMPACT HD™ Mass Spectrometer with Novel CaptiveSpray™ nanoBooster Ion Source

At the 61st ASMS conference, Bruker introduces exciting new High-Definition capabilities in proteomics and biomarker research. Patented low-noise Captivespray nanoBooster™ ionization coupled with record high-speed digitization Qq-TOF technology and steered by intelligent acquisition software defines complex samples more sharply than ever before.

10 Jun 2013

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

At the 61st ASMS Conference on Mass Spectrometry and Allied Topics, Bruker today announced mass spectrometry-based product introductions for life-science and clinical research, for biotech/pharma/CRO customers, as well as for industrial and applied markets. The new mass spectrometry systems and solutions are designed to deliver confident analyses with dramatically enhanced resolution, sensitivity and precision.

10 Jun 2013

New LC-MS software to transform high performance mass spectrometry unveiled by Thermo Fisher Scientific

Thermo Fisher Scientific Inc., the world leader in serving science, today introduced 10 new or updated software packages to help customers harness the power of its new-generation liquid chromatography-mass spectrometry (LC-MS) instruments and turn data into knowledge in a wide range of discovery and quantitation experiments.

From Thermo Fisher Scientific Inc. 10 Jun 2013

Researchers move closer to specific therapy to treat triple receptor-negative breast cancer

The search for a specific therapy to treat a particularly aggressive type of breast cancer has moved a step forward thanks to new research carried out by the University of Essex.

10 Jun 2013

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Funded by volleyball tournaments, a new study released this week shows success in pinpointing individualized treatment for women with metastatic breast cancer, according to George Mason University researchers.

6 Jun 2013

Molecular switch protects salmonella from harm during infection

For the first time, researchers have found a particular kind of molecular switch in the food poisoning bacteria Salmonella Typhimurium under infection-like conditions. This switch, using a process called S-thiolation, appears to be used by the bacteria to respond to changes in the environment during infection and might protect it from harm, researchers report this week online in the Proceedings of the National Academy of Sciences Early Edition.

28 May 2013

Proteomics News and Research

Further Reading

CLAMP: A newly discovered protein that regulates genes

Breast cancer pilot study: Patients benefit from treatments guided by molecular profiling

Microfuge 20 and 20R microcentrifuges from Beckman Coulter Life Sciences simplify setup, offer increased speed and capacity

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

C2N Diagnostics, CIL sign collaborative research and global supplier agreement

Researchers are one step closer to finding solution for atherosclerosis in diabetic patients

Collaborative research yields a wiring map on how TB responds to changes in environment

Salsalate lowers blood glucose and improves glycemic control in T2D, say scientists

Research suggests new models for study of Barrett's esophagus

PLK1 crucial for proper functioning of cancer cells, researchers reveal

VILLUM Foundation grants $10.6 M to the University of Southern Denmark

SAP and TUM decode human proteome and provide data for biomedical research

Studies demonstrate that combined therapy could destroy drug-resistant cells within melanoma tumor

Rapamycin improves cardiac function in mice suffering from age-related heart disease

Sensational proteomics results enabled by Bruker’s new IMPACT HD™ Mass Spectrometer with Novel CaptiveSpray™ nanoBooster Ion Source

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

New LC-MS software to transform high performance mass spectrometry unveiled by Thermo Fisher Scientific

Researchers move closer to specific therapy to treat triple receptor-negative breast cancer

Study shows success in pinpointing individualized treatment for women with metastatic breast cancer

Molecular switch protects salmonella from harm during infection

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