Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Switzerland creates new centre for vaccine research

The Institute will develop an immunology, microbiology and vaccine research laboratory platform to encourage cooperation between scientists working in the field of HIV, malaria, tuberculosis, influenza and cancer vaccine development in Switzerland, from fundamental to clinical researchers.

4 Dec 2007

Researchers outline structure of largest nonvirus particle ever crystallized

Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery.

27 Nov 2007

From successful aging to severe dementia

A recently published special issue of the Journal of Alzheimer's Disease contains the contributions from experts in the field of aging, dementia and Alzheimer's disease, who attended the "Fourth Annual Meeting on Brain aging and Dementia - From successful aging to severe dementia”, Held in Perugia in October 2006 under the auspices of the Italian Psychogeriatric Association, a member of the International Psychogeriatric Association, the meeting celebrates the centenary of Alzheimer's first description of the disease.

16 Nov 2007

Micro Petri dish allows unprecedented miniaturisation of the growth of micro-organisms

Scientists of Top Institute Food & Nutrition, Wageningen University and Research Centre, NIZO food research and the MESA+ Institute for Nanotechnology in the Netherlands have developed a new technology that allows unprecedented miniaturisation of the growth of micro-organisms.

13 Nov 2007

Overexpression of neuroglobin reduces severity of Alzheimer's disease in mice

Mice genetically engineered to both overproduce the protein neuroglobin and to develop Alzheimer's disease (AD) had a much milder form of the disease when compared to mice engineered to have AD alone, researchers at the Buck Institute for Age Research have reported.

13 Nov 2007

Lithium commonly used to treat bi-polar disorder increases lifespan in Nematode worms

Nematode worms treated with lithium show a 46 percent increase in lifespan, raising the tantalizing question of whether humans taking the mood affecting drug are also taking an anti-aging medication.

31 Oct 2007

New imaging technique ensures rapid profiling of autoantibodies in rheumatoid arthritis

Using a new imaging technique, a fast and accurate profile of autoantibodies present in the blood serum of rheumatic patients can be made.

25 Oct 2007

Transthyretin protein may accelerate atherosclerosis

Scientists report in the November 2007 issue of the Journal of Lipid Research that a protein called transthyretin (TTR) that is present in the blood may accelerate the development of atherosclerosis - a potentially fatal heart disease in which the arteries are progressively narrowed and hardened over time, reducing blood flow to the heart.

12 Oct 2007

Peripheral ehanolamine plasmalogen deficiency - likely factor in Alzheimer's and dementia

Dayan B. Goodenowe and colleagues report in the November 2007 issue of the Journal of Lipid Research that people with Alzheimer's disease and related conditions exhibit decreased blood levels of an important brain chemical called ethanolamine plasmalogen, even at the very early stages of the disease.

12 Oct 2007

Potential health benefits of fish oil in baby formula

Scientists report in the November 2007 issue of the Journal of Lipid Research that adding long-chain polyunsaturated fatty acids - typically found in fish oil - to baby formula may help infants better regulate their blood sugar and make more proteins in their muscle cells.

12 Oct 2007

Compound called apolipoprotein B in blood better at predicting coronary heart disease in Chinese people

Scientists report in the November 2007 issue of the Journal of Lipid Research that the concentration of a compound called apolipoprotein B in the blood is better at predicting whether Chinese have coronary heart disease – in which fatty deposits clog arteries that supply blood and oxygen to the heart – than other substances such as blood cholesterol levels.

12 Oct 2007

Researchers report most complete list so far of the proteins present in the cerebral cortex

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics the most complete list so far of the proteins present in the cerebral cortex – the outermost layer of the brain that plays a central role in memory, language, cognition, and consciousness.

8 Oct 2007

Proteins found that could be used to improve diagnosis of hepatocellular carcinoma

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have identified proteins that could be used to improve the diagnosis of hepatocellular carcinoma, the most common type of liver cancer.

8 Oct 2007

Improving diagnosis of cancer by detecting protein-sugar structures

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have developed a new way of detecting the abnormal presence of complexes of sugars and proteins in the blood of cancer patients, thus providing a new tool for cancer diagnosis.

8 Oct 2007