Proteostasis News and Research

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Each mammalian cell contains up to 20,000 proteins, all of which must be maintained and regulated. Proteostasis is a complex pathway that functions to maintain all of the proteins within and around a cell.
FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

How does dietary intervention affect aging?

How does dietary intervention affect aging?

Study reveals a new pathway for how children and adults develop cardiomyopathy

Study reveals a new pathway for how children and adults develop cardiomyopathy

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

New research extensively explores 12 distinctive aging traits

New research extensively explores 12 distinctive aging traits

Researchers corroborate the importance of exercise for cognitive function

Researchers corroborate the importance of exercise for cognitive function

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

SARS-CoV-2-encoded protein ameliorates neuromuscular degeneration in fly models of neurodegenerative diseases

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

How diet and nutrition impacts lifespan

How diet and nutrition impacts lifespan

New mouse line reveals the state of protein balance in the mammalian brain for the first time

New mouse line reveals the state of protein balance in the mammalian brain for the first time

UC San Diego scientists develop new method to keep cultured cells healthy

UC San Diego scientists develop new method to keep cultured cells healthy

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Study may lead to new treatments for a wide range of neurological conditions

Study may lead to new treatments for a wide range of neurological conditions

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Experimental drug reverses key symptoms of Alzheimer's disease in mice

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

Researchers describe a new approach to treating Parkinson's disease

Researchers describe a new approach to treating Parkinson's disease

Researchers use EPR spectroscopy to learn more about "Parkinson protein"

Researchers use EPR spectroscopy to learn more about "Parkinson protein"

Potential new treatment approach to fatal COVID-19

Potential new treatment approach to fatal COVID-19

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

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