Proteostasis News and Research

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Each mammalian cell contains up to 20,000 proteins, all of which must be maintained and regulated. Proteostasis is a complex pathway that functions to maintain all of the proteins within and around a cell.
CheekAge: Next-gen epigenetic clock accurately predicts mortality risk

CheekAge: Next-gen epigenetic clock accurately predicts mortality risk

New genetic mutation may cause a form of early-onset Parkinsonism

New genetic mutation may cause a form of early-onset Parkinsonism

Researchers identify drug with anti-aging effects

Researchers identify drug with anti-aging effects

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

PhoreMost introduces GlueSEEKER platform for discovery of molecular glue degraders

PhoreMost introduces GlueSEEKER platform for discovery of molecular glue degraders

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Magnesium's pivotal role in slowing aging's impact

Magnesium's pivotal role in slowing aging's impact

New method traces primed resistance in cancer via sister cells

New method traces primed resistance in cancer via sister cells

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

Researchers evaluate possible mitochondrial factors in Alzheimer's pathogenesis

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Can coffee silverskin be used to prevent aging?

Can coffee silverskin be used to prevent aging?

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

New small molecule drug targets active state of cancer-causing KRAS mutant

New small molecule drug targets active state of cancer-causing KRAS mutant

Study reveals how p62 bodies control redox-independent stress response

Study reveals how p62 bodies control redox-independent stress response

How does tirzepatide stimulate insulin secretion?

How does tirzepatide stimulate insulin secretion?

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

Integrated proteomics approach identifies the contents of p62 bodies in detail

Integrated proteomics approach identifies the contents of p62 bodies in detail

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

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