Proteostasis News and Research

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Each mammalian cell contains up to 20,000 proteins, all of which must be maintained and regulated. Proteostasis is a complex pathway that functions to maintain all of the proteins within and around a cell.
Potential new treatment approach to fatal COVID-19

Potential new treatment approach to fatal COVID-19

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Researchers establish a gene expression profile associated with cachexia in cancer patients

Researchers establish a gene expression profile associated with cachexia in cancer patients

ADDF announces new awards through its Diagnostics Accelerator initiative

ADDF announces new awards through its Diagnostics Accelerator initiative

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Scientists demonstrate influence of food odors on proteostasis

Scientists demonstrate influence of food odors on proteostasis

Antibiotic could protect against age-related brain diseases

Antibiotic could protect against age-related brain diseases

Researchers acquire new insights into DNA polymerases

Researchers acquire new insights into DNA polymerases

Scientists take important step to understand mechanisms that cause Huntington's disease

Scientists take important step to understand mechanisms that cause Huntington's disease

Researchers find link between increased proteostasis and immortality of stem cells

Researchers find link between increased proteostasis and immortality of stem cells

Research findings could help understand how Parkinson's develops on molecular level

Research findings could help understand how Parkinson's develops on molecular level

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

Scientists identify how tumor cells exploit function of mitochondria to support cancer proliferation

Scientists uncover small set of genes critical in aging and neurodegenerative disease

Scientists uncover small set of genes critical in aging and neurodegenerative disease

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Einstein-Montefiore researchers to present latest finding on aging research at GSA 2014

Researchers examine how basic biology of aging drives chronic disease

Researchers examine how basic biology of aging drives chronic disease

TSRI scientists discover natural mechanism that cells use to protect mitochondria

TSRI scientists discover natural mechanism that cells use to protect mitochondria