Proteostasis News and Research

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Each mammalian cell contains up to 20,000 proteins, all of which must be maintained and regulated. Proteostasis is a complex pathway that functions to maintain all of the proteins within and around a cell.
Study may lead to new treatments for a wide range of neurological conditions

Study may lead to new treatments for a wide range of neurological conditions

Experimental drug reverses key symptoms of Alzheimer's disease in mice

Experimental drug reverses key symptoms of Alzheimer's disease in mice

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

Researchers describe a new approach to treating Parkinson's disease

Researchers describe a new approach to treating Parkinson's disease

Researchers use EPR spectroscopy to learn more about "Parkinson protein"

Researchers use EPR spectroscopy to learn more about "Parkinson protein"

Potential new treatment approach to fatal COVID-19

Potential new treatment approach to fatal COVID-19

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

Researchers discover a new mode of protein degradation by ubiquitin-proteasome system

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Researchers establish a gene expression profile associated with cachexia in cancer patients

Researchers establish a gene expression profile associated with cachexia in cancer patients

ADDF announces new awards through its Diagnostics Accelerator initiative

ADDF announces new awards through its Diagnostics Accelerator initiative

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Scientists reverse learning and memory deficits with drugs in animal model of Down syndrome

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Stony Brook-led study reveals how proteome collapse process drives cell death and aging

Scientists demonstrate influence of food odors on proteostasis

Scientists demonstrate influence of food odors on proteostasis

Antibiotic could protect against age-related brain diseases

Antibiotic could protect against age-related brain diseases

Researchers acquire new insights into DNA polymerases

Researchers acquire new insights into DNA polymerases

Scientists take important step to understand mechanisms that cause Huntington's disease

Scientists take important step to understand mechanisms that cause Huntington's disease

Researchers find link between increased proteostasis and immortality of stem cells

Researchers find link between increased proteostasis and immortality of stem cells

Research findings could help understand how Parkinson's develops on molecular level

Research findings could help understand how Parkinson's develops on molecular level

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells

Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells