Quorum Sensing News and Research

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Researchers develop technique to disrupt communication between microorganisms

The World Health Organization considers Pseudomonas aeruginosa a germ requiring urgent action to prevent and control its spread. The bacteria can cause a variety of diseases from chronic lung infections to sepsis.

8 Nov 2018

Researchers discover new antibiotic compounds

Researchers have identified new compounds that can target bacterial infection, potentially providing an answer to antibiotic resistance.

1 Nov 2018

Neem Biotech granted two funding awards by Welsh Government for work in antimicrobial resistance

Neem Biotech’s work is boosted by two separate funding grants from the Welsh Government and European Regional Development Fund

From Neem Biotech 29 Oct 2018

A genetic signal-transmission system for the gut microbiome

More than 1,000 species of bacteria have been identified in the human gut, and understanding this incredibly diverse "microbiome" that can greatly impact health and disease is a hot topic in scientific research.

31 Aug 2018

Chemists synthesize garlic ingredient from readily available components

Fresh garlic extracts contain a variety of healthy organosulfur compounds, among which ajoene forms a major oil-extractable ingredient.

24 Aug 2018

Wound healing work presented at the RCP Innovation in Medicine Conference 2018 by Neem Biotech

Neem Biotech recently attended the Royal College of Physicians’ Innovation in Medicine Conference 2018 where Neem presented their data around wound-relevant biofilms.

From Neem Biotech 23 Aug 2018

Innovation in Wound Care

There are many definitions of hard-to-heal. More conventionally, it's based on underlying etiology of the wound, but in practice it's any wound that has not healed within a timely fashion. This is often due to a lack of coordinated care.

From Neem Biotech 22 Aug 2018

Study sheds new light on how the food we eat affects biochemical signals in the gut

For years, researchers have studied how the body's microbiome impacts virtually every aspect of human health ranging from the immune system to mental wellness.

5 Jun 2018

Study shows nitric oxide inhibits S. aureus bacteria from transforming to its virulent form

According to the U.S. Centers for Disease Control and Prevention, about one in three humans carries Staphylococcus aureus, or "staph," in our noses, and 2 percent of us carry the dreaded methicillin-resistant (MRSA) strain that thwarts common antibiotics.

27 Apr 2018

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Neem Biotech, a Wales-based R&D biotech working in the field of novel antimicrobial drug development, announced today that it will be presenting results of its ongoing development work into the impact of NX-AS-401, its lead candidate,on biofilms in chronic cystic fibrosis lung infections at the 15th European Cystic Fibrosis Basic Science Conference taking place from 21st to 24th March 2018 in LoutrakiKorinthias, Greece.

From Neem Biotech 22 Mar 2018

UIC scientists identify new chemical compound to stop bacteria from causing sickness

A study published in the Journal of Biological Chemistry is the first to describe a signaling pathway that affects communication -- a process called quorum sensing -- between Streptococcus bacteria cells.

6 Feb 2018

Researchers identify promising solution for improving cystic fibrosis treatments

Researchers at the University of Montreal Hospital Research Centre have identified a promising solution to improving treatments offered to patients with cystic fibrosis.

12 Dec 2017

Quorum sensing data presented at the North American Cystic Fibrosis Conference by Neem Biotech

Neem Biotech, the Welsh-based fundamental Research and Development arm of the Zaluvida group of life science companies, was pleased to present the work into development of a novel mode of action as an adjunct to existing antibiotics at the North American Cystic Fibrosis Conference Indiana, USA from 2nd November 2017 to 4th of November 2017.

From Neem Biotech 6 Nov 2017

An alternative approach to augmenting the effect of antibiotics in chronic CF lung infections

There are about 77,000 people known to have cystic fibrosis. That's from the various cystic fibrosis registries available globally. The World Health Organization suggests that this number may be low, because there's no reporting on cystic fibrosis from the developing world. The accepted number, at the moment, is about 80,000. That's the one that is used for most of the work that's being done on cystic fibrosis.

From Neem Biotech 3 Nov 2017

Scientists reveal existence of alternative bacterial quorum-sensing mechanism

Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to carry out individually.

21 Aug 2017

Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters

Bacteria have supplied some of today's most indispensable anti-cancer and anti-bacterial drugs. Yet these compounds comprise only a fraction of their possible offerings. Now, researchers have found a way to unleash their full potential as natural product dispensers.

13 Apr 2017

Innovative ways to target antibiotic resistance in short term

There has been much recent talk about how to target the rising tide of antibiotic resistance across the world, one of the biggest threats to global health today.

3 Mar 2017

Cranberry extract disrupts communication between bacteria linked to pervasive infections

Scientists from McGill University and INRS-Institut Armand-Frappier in Canada recently released a novel investigation showing that cranberry extract successfully interrupted the communication between bacteria associated with problematic and pervasive infections.

25 Oct 2016

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted.

2 Apr 2016

New method could help physicians detect infection in wounds in less than a minute

A new method for detection of infection in wounds could take physicians less than a minute to complete, rather than the current 24 hours it takes to plate bacteria and leave it to incubate overnight, according to research by the George Washington University's Victoria Shanmugam, M.D.

7 Feb 2016