RNA Sequencing News and Research

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Researchers develop new software tool to provide fast, accurate quantification of gene expression

A group of computational biological researchers, led by Stony Brook University's Rob Patro, an Assistant Professor in the Department of Computer Science in the College of Engineering and Applied Sciences, has developed a new software tool, Salmon — a lightweight method to provide fast and bias-aware quantification from RNA-sequencing reads.

22 Mar 2017

Single-cell transcriptomic analysis uncovers subgroups of colorectal tumors

Combining single-cell genomics and computational techniques, a research team including Paul Robson, Ph.D., director of single-cell biology at The Jackson Laboratory, has defined cell-type composition of cancerous cells from 11 colorectal tumors, as well as adjacent noncancerous cells, a key to more targeted diagnosis and treatment.

20 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Linking RNA to autoimmune diseases

An interview with Dr. Chase Spurlock, CEO, discussing IQuity's research into IncRNAs and how they are linked to autoimmue diseases.

20 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Researchers suggest potential new way to restore healthy intestinal function in older people

Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity.

15 Mar 2017

Researchers identify genetic variants that may contribute to schizophrenia

New research has identified sections of DNA associated with altered regulation of gene expression underlying schizophrenia.

27 Feb 2017

MSK researchers publish new review that focuses on genome-driven oncology

Researchers from Memorial Sloan Kettering Cancer Center today published a seminal review of the rapidly evolving field of precision oncology, which allows doctors to recommend therapies based on a genetic understanding of a person's cancer.

9 Feb 2017

Researchers map genetic changes resulting from short bowel syndrome

Investigators at Children's Hospital Los Angeles, led by Tracy C. Grikscheit, MD, have mapped the genetic changes resulting from short bowel syndrome using a novel zebrafish model and by performing intensive gene sequencing.

25 Jan 2017

New research exposes cellular responses linked to bird flu vaccine

New research from Vanderbilt eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu.

19 Jan 2017

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets.

19 Jan 2017

Researchers identify brain cell types from cell culture of adult human neurons

Studying brain disorders in people and developing drugs to treat them has been slowed by the inability to investigate single living cells from adult patients

18 Jan 2017

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Diet-related diseases like non-alcoholic fatty liver disease (NAFLD) are known to have a major inflammatory component.

21 Dec 2016

Researchers uncover neural progenitors in protective membranes covering the brain

In a cross-domain study directed by professor Peter Carmeliet (VIB - KU Leuven), researchers discovered unexpected cells in the protective membranes that enclose the brain, the so called meninges.

24 Nov 2016

New research shows impact of fiber deprivation on mouse gut

It sounds like the plot of a 1950s science fiction movie: normal, helpful bacteria that begin to eat their host from within, because they don't get what they want.

17 Nov 2016

Researchers create temporal and spatial atlas that plots development of mouse heart

It's not simple, making a heart. In the womb, the organ begins as a tube, sprouts bead-like lumps, folds in on itself and eventually morphs into the more familiar-looking four-chambered structure.

17 Nov 2016

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

An international research team led by St. Jude Children's Research Hospital investigators has uncovered details of a new, high-risk subtype of acute lymphoblastic leukemia (ALL) as well as a possible targeted therapy.

8 Nov 2016

Scientists identify commonly affected genes sets among people with three mental disorders

Studying brain tissue from deceased donors, Johns Hopkins scientists have found common groups of genes disrupted among people with schizophrenia, bipolar disorder and major depression.

26 Oct 2016

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

A project led by the Spanish National Research Council (CSIC) researcher, Alejandro Toledo-Arana, at the Institute of Agro biotechnology (a centre shared between CSIC, the Public University of Navarra and The Regional Government of Navarra), is studying new genetic regulatory mechanisms in pathogenic bacteria.

26 Oct 2016

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published October 14th, 2016 in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

17 Oct 2016

RNA Sequencing News and Research

Researchers develop new software tool to provide fast, accurate quantification of gene expression

Single-cell transcriptomic analysis uncovers subgroups of colorectal tumors

Circadian misalignments may favor diabetes development

Linking RNA to autoimmune diseases

LJI researchers unravel molecular underpinnings of exhausted T cells

Researchers suggest potential new way to restore healthy intestinal function in older people

Researchers identify genetic variants that may contribute to schizophrenia

MSK researchers publish new review that focuses on genome-driven oncology

Researchers map genetic changes resulting from short bowel syndrome

New research exposes cellular responses linked to bird flu vaccine

CeMM scientists develop new method by integrating CRISPR genome editing with single-cell sequencing

Researchers identify brain cell types from cell culture of adult human neurons

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Researchers uncover neural progenitors in protective membranes covering the brain

New research shows impact of fiber deprivation on mouse gut

Researchers create temporal and spatial atlas that plots development of mouse heart

Researchers uncover possible targeted therapy for new, high-risk subtype of ALL

Scientists identify commonly affected genes sets among people with three mental disorders

CSIC project aims to study new genetic regulatory mechanisms in pathogenic bacteria

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

Sequencing & Genomics: Elevating Science and Healthcare eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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