RNA Sequencing News and Research

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INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

INTEGRA Biosciences and Parse Biosciences have partnered to automate single cell RNA sequencing (scRNA-seq) on the ASSIST PLUS pipetting robot.

From INTEGRA Biosciences 26 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Neuroscientists discover a key piece of the placebo effect puzzle

The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially pain.

24 Jul 2024

'Gene misbehavior' found to be surprisingly common among the healthy population

Scientists have uncovered that 'gene misbehavior' – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

24 Jul 2024

AI model enhances DCIS diagnosis using tissue image analysis

Ductal carcinoma in situ (DCIS) is a type of preinvasive tumor that sometimes progresses to a highly deadly form of breast cancer. It accounts for about 25 percent of all breast cancer diagnoses.

24 Jul 2024

CePA: Novel nanomedicine for alleviating MASH via mTOR repression

Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic liver diseases, primarily caused by metabolic disorders and systemic inflammatory responses.

16 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Study identifies RFC4 as key player in nasopharyngeal carcinoma

Lichuan Wu et al., at Medical College of Guangxi University, China, presented a comprehensive study on the role of replication factor C subunit 4 (RFC4) in nasopharyngeal carcinoma (NPC), a type of epithelial cancer commonly associated with Epstein-Barr virus infection.

12 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Advancing genomics research: An inside look at Azenta Life Sciences' new Oxford Genomics Laboratory

This interview delves into the capabilities and services of Azenta Life Sciences' new Oxford Genomics Laboratory, discussing its role in advancing genomic research in the UK, the unique setup process, and future expansion plans.

From GENEWIZ from Azenta Life Sciences 8 Jul 2024

Repurposing cancer drug to prevent organ damage in infectious diseases

Twelve years ago, cancer researchers at University of California San Diego identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue.

3 Jul 2024

New study reveals ketogenic diet's role in combating obesity

Researchers showed that ketogenic diet (KD)-induced bile acids (BAs) are protective against obesity.

1 Jul 2024

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.

28 Jun 2024

Study reveals novel therapeutic approach for excessive alcohol use

In a significant finding, researchers from The Jackson Laboratory (JAX) and UConn Health have discovered that sodium valerate, a short-chain fatty acid produced by gut microbes, can dramatically reduce binge drinking behavior and blood ethanol concentration in mice.

25 Jun 2024

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.

25 Jun 2024

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Researchers analyzed early immune responses to SARS-CoV-2 using single-cell multi-omics, revealing key cellular states associated with different infection outcomes.

24 Jun 2024

Dietary sucrose modulates lithium's regulatory activity in Drosophila

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Dietary sucrose determines the regulatory activity of lithium on gene expression and lifespan in Drosophila melanogaster."

24 Jun 2024

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Liver transplants associated with alcohol-related disease are growing at a rapid pace, shifting research to address pathologies behind the ailments in light of a limited supply of organ donors.

21 Jun 2024

Unveiling the role of auto-antibodies in COVID-19 severity

Even though COVID-19 manifests as a mild and short-lived disease in most people, some suffer extremely severe symptoms; in the worst cases, these patients die due to complications such as respiratory failure or thromboembolism.

19 Jun 2024

RNA Sequencing News and Research

INTEGRA Biosciences and Parse Biosciences offer affordable, automated single cell RNA sequencing

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Neuroscientists discover a key piece of the placebo effect puzzle

'Gene misbehavior' found to be surprisingly common among the healthy population

AI model enhances DCIS diagnosis using tissue image analysis

CePA: Novel nanomedicine for alleviating MASH via mTOR repression

Researchers discover key functions of IRF1 in cancer progression and treatment response

Study identifies RFC4 as key player in nasopharyngeal carcinoma

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Advancing genomics research: An inside look at Azenta Life Sciences' new Oxford Genomics Laboratory

Repurposing cancer drug to prevent organ damage in infectious diseases

New study reveals ketogenic diet's role in combating obesity

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

Study reveals novel therapeutic approach for excessive alcohol use

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Study reveals early immune responses to SARS-CoV-2, offering insights for future COVID-19 treatments

Dietary sucrose modulates lithium's regulatory activity in Drosophila

UT Health San Antonio researcher wins NIH grant to investigate alcohol-associated liver disease

Unveiling the role of auto-antibodies in COVID-19 severity

Sequencing & Genomics: Elevating Science and Healthcare eBook

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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