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Brain response patterns to rewards may be influenced by gene variants affecting pain sensitivity

Patterns of brain responses to rewards are a significant predictor of pain symptoms—a link that is already present by adolescence—and may be influenced by gene variants affecting pain sensitivity, reports a study in PAIN, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer.

28 Jan 2017

Both accelerator and brake in the brain control all types of movements, research shows

In order to drive a car, you need a good balance between accelerator and brake. The same applies to a part of the brain - the striatum - that controls our movements.

28 Jan 2017

TSRI biologists identify brain hormone that selectively stimulates fat metabolism

Biologists at The Scripps Research Institute have identified a brain hormone that appears to trigger fat burning in the gut. Their findings in animal models could have implications for future pharmaceutical development.

27 Jan 2017

LSD influences perception by stimulating serotonin receptors in the brain

Researchers from UZH have discovered how the perception of meaning changes in the brain under the influence of LSD. The serotonin 2A receptors are responsible for altered perception.

27 Jan 2017

Old tuberculosis drug improves impaired social behavior in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry.

26 Jan 2017

HCI scientists uncover new way that bones get destroyed through breast cancer

Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute at the University of Utah have identified a new way that bones get destroyed through cancer.

25 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Advanced NMR-based methods for studying RNPs and drug design

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool widely used in chemical research to investigate the structure and dynamics of molecules.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jan 2017

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.

20 Jan 2017

Study provides scientific insight into metastatic patterns of EGFR mutated NSCLCs

The discovery of several different subtypes of Non Small Cell Lung Cancer (NSCLC), the most frequent form of lung cancer, has been a major breakthrough in the fight against the leading cause of cancer-related death worldwide.

20 Jan 2017

Study reveals mechanism for illness-induced sleepiness in humans and animals

It's well known that humans and other animals are fatigued and sleepy when sick, but it's a microscopic roundworm that's providing an explanation of how that occurs, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Jan 2017

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found.

19 Jan 2017

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Mutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report.

19 Jan 2017

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression.

19 Jan 2017

Exercise helps mitigate side effects of AIs in breast cancer survivors

A researcher at Syracuse University has simple advice for breast cancer survivors struggling with the side effects of Aromatase Inhibitors (AIs): exercise.

19 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Research shows role played by PAMPs in immune system signaling and response

How big you are may be as important as what you look like, at least to immune system cells watching for dangerous bacteria and viruses.

18 Jan 2017

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds.

18 Jan 2017

Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Researchers from the University of California and Cardiff University have made a breakthrough in the understanding of AIDS-related dementia, discovering the role of a neuron protein which was also found to affect learning abilities in healthy subjects.

18 Jan 2017

Analgesic effects of opioids can be mediated via immune cells

Opioids are the most powerful painkillers. Researchers at the Charité - Universitätsmedizin Berlin have now found that the analgesic effects of opioids are not exclusively mediated by opioid receptors in the brain, but can also be mediated via the activation of receptors in immune cells.

17 Jan 2017

Receptor News and Research

Brain response patterns to rewards may be influenced by gene variants affecting pain sensitivity

Both accelerator and brake in the brain control all types of movements, research shows

TSRI biologists identify brain hormone that selectively stimulates fat metabolism

LSD influences perception by stimulating serotonin receptors in the brain

Old tuberculosis drug improves impaired social behavior in autism mouse model

HCI scientists uncover new way that bones get destroyed through breast cancer

Scientists discover new way to inhibit growth of glioblastoma

Advanced NMR-based methods for studying RNPs and drug design

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Study provides scientific insight into metastatic patterns of EGFR mutated NSCLCs

Study reveals mechanism for illness-induced sleepiness in humans and animals

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Mutations in gene that enables memories, sense of direction can contribute to schizophrenia symptoms

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Exercise helps mitigate side effects of AIs in breast cancer survivors

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Research shows role played by PAMPs in immune system signaling and response

Protein involved in pancreatic cancer development plays more complicated role, study finds

Researchers discover role of neuron protein in learning abilities and AIDS-related dementia

Analgesic effects of opioids can be mediated via immune cells

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Expanding research and clinical options for children with cancer

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