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Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.

15 Dec 2016

New duo therapy offers hope for 'super blockage' of over-active immune system

A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.

15 Dec 2016

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Around 20% of breast cancer patients do not complete prescribed endocrine therapy, researchers report at the ESMO Asia 2016 Congress in Singapore.1 The study in over 5,500 women found that younger patients and those who had taken hormone replacement therapy (HRT) were less likely to adhere to their medicine.

14 Dec 2016

UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

The University of Nebraska Medical Center is seeking 24 patients to enroll in a Phase 2a study to evaluate the safety and efficacy of two oral cancer drugs for patients with diffuse large B-cell lymphoma who have relapsed or are resistant to other traditional therapies.

9 Dec 2016

Depression drug can alleviate joint pain in postmenopausal women treated for breast cancer

A drug typically used to treat depression and anxiety can significantly reduce joint pain in postmenopausal women being treated for early stage breast cancer, according to new SWOG research to be presented Friday at a special plenary presentation at the San Antonio Breast Cancer Symposium.

9 Dec 2016

Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments.

9 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key.

6 Dec 2016

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty.

6 Dec 2016

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells.

6 Dec 2016

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

A promising new combination therapy for a particularly aggressive form of breast cancer has been identified by Weizmann Institute scientists, as was recently reported in Cancer Research.

5 Dec 2016

Auditory deficits in people with schizophrenia linked to dysfunctional brain receptors

The inability to hear subtle changes in pitch, a common and debilitating problem for people with schizophrenia, is due to dysfunctional N-methyl-D-aspartate (NMDA) brain receptors, according to a study by Columbia University Medical Center researchers.

2 Dec 2016

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Major improvement in the diagnosis of Chronic Fatigue Syndrome is expected following the award of $4m in funding to one of Australia’s foremost authorities on the condition.

2 Dec 2016

Monell Center receives Gates Foundation grant to support innovative global health research project

The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."

1 Dec 2016

Receptor News and Research

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

New duo therapy offers hope for 'super blockage' of over-active immune system

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

Depression drug can alleviate joint pain in postmenopausal women treated for breast cancer

Controversial hormone could fight against recurring breast cancers

Enzyme that cleaves beta carotene may control testosterone levels

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Experimental T-cell therapy shows promise in preventing AML relapse

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

Auditory deficits in people with schizophrenia linked to dysfunctional brain receptors

Researchers receive Stafford Fox Medical Research Foundation grant to accelerate CFS diagnosis

Monell Center receives Gates Foundation grant to support innovative global health research project

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

TSRI scientists discover potential drug candidate to suppress pain and itch

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

Scientists identify cell-surface receptor for progranulin

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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