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New leads for the discovery of anthrax antitoxins that could be used in conjunction with antibiotics to treat late-stage anthrax

A team of researchers led by The Burnham Institute’s Robert C. Liddington has determined the crystal structure of the binding complex between anthrax toxin and one of its host receptors.

8 Jul 2004

New guidelines for treating heart attacks

If your chest pain worsens and lasts more than five minutes, especially if you’re short of breath, feel weak, nauseated or lightheaded, call 9-1-1—you could be having a heart attack.

8 Jul 2004

New imaging agent will enable doctors to rapidly and accurately detect those hard-to-diagnose appendicitis cases

About half of the 700,000 annual cases of suspected appendicitis in the United States lack the usual symptoms – pain in the lower right abdomen, fever and a rising white blood cell count – making the decision to operate somewhat problematic.

7 Jul 2004

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Treatment with a new dual cell cycle and angiogenesis pathway inhibitor blocks VEGF-induced vascular permeability, inhibits tumour angiogenesis and induces apoptosis in human tumour models

7 Jul 2004

Research points to a possible way to design anthrax toxin molecules that selectively attack tumor cells

Scientists have determined a three-dimensional (3-D) molecular image of how anthrax toxin enters human cells, giving scientists more potential targets for blocking the toxin, the lethal part of anthrax bacteria.

5 Jul 2004

ASU and Mayo Clinic collaborate on a new joint nursing program

ASU and Mayo Clinic have reached an agreement to collaborate on a new joint nursing program based at Mayo Clinic Hospital in northeast Phoenix.

2 Jul 2004

New drug application for cilansetron, an investigational product for the treatment of irritable bowel syndrome

Solvay Pharmaceuticals, Inc. has submitted a New Drug Application (NDA) for cilansetron, an investigational product being studied for the treatment of irritable bowel syndrome with diarrhea predominance (IBS-D), to the FDA on June 30, 2004.

1 Jul 2004

Exelixis files new drug application for a proprietary novel anticancer compound

Exelixis, Inc. has submitted an investigational new drug application (IND) to the U.S. Food and Drug Administration (FDA) for XL999, a proprietary novel anticancer compound.

29 Jun 2004

Scientists use genetic engineering to work out how odors are encoded

Yale scientists, working with the fruit fly as a model, have discovered how odors are encoded by the olfactory system into the complex messages that are sent to the brain.

26 Jun 2004

European Commission has approved the use of Herceptin® (trastuzumab) in combination with Taxotere®

The approval is based on study results which showed that for women with HER2-positive breast cancer, the combination of Herceptin and Taxotere significantly improved median life expectancy by more than one-third (31 months with Herceptin plus Taxotere vs. 22 months for Taxotere alone).

23 Jun 2004

Drug for multiple sclerosis prevented disease development when tested on animal models

Scientists from the Neurological Sciences Institute at Oregon Health & Science University have shown that an investigative drug for multiple sclerosis and related diseases prevented disease development when tested on animal models.

20 Jun 2004

Valsartan may reduce cardiac illness and death

Results of a study in this week's issue of THE LANCET provide further evidence that a class of drugs that lower blood pressure are a treatment option for older people at high cardiovascular risk. The study also emphasises the importance of early blood-pressure lowering after the start of treatment to reduce the risk of cardiovascular events such as heart attack and stroke.

17 Jun 2004

Harmless virus known as GBV-C slows the progression of HIV

Iowa City Veterans Affairs (VA) Medical Center and University of Iowa (UI) researchers have unlocked part of the mystery of how a harmless virus known as GBV-C slows the progression of HIV and prolongs survival for many patients.

17 Jun 2004

Further evidence that a class of drugs that lower blood pressure are a treatment option for older people at high cardiovascular risk

Results of a study in this week’s issue of THE LANCET provide further evidence that a class of drugs that lower blood pressure are a treatment option for older people at high cardiovascular risk. The study also emphasises the importance of early blood-pressure lowering after the start of treatment to reduce the risk of cardiovascular events such as heart attack and stroke.

17 Jun 2004

Marijuana/Cannabis causes transient schizophrenia-like symptoms

The principal active ingredient in marijuana causes transient schizophrenia-like symptoms ranging from suspiciousness and delusions to impairments in memory and attention, according to a Yale research study.

15 Jun 2004

Cancer drug gefitinib (Iressa) may be able to restore tamoxifen's anticancer activity

A new study has found a possible mechanism for tamoxifen resistance in breast cancer and provides evidence that another cancer drug--gefitinib (Iressa)--may be able to restore tamoxifen's anticancer activity.

15 Jun 2004

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get. If a woman is found to have high blood sugar when she's pregnant, but she never had high blood sugar before, she has gestational diabetes.

15 Jun 2004

What causes polycystic ovary syndrome?

A woman finds herself with excessive facial hair, obesity, menstrual abnormalities, infertility, and enlarged ovaries may have polycystic ovary syndrome (PCOS), an unfortunate condition thought to be caused by excessive secretion by the ovaries of androgen, a hormone associated with male characteristics.

15 Jun 2004

African-American women less likely to survive breast cancer than white women

A new study led by investigators at Fred Hutchinson Cancer Research Center may help explain why African-American women with breast cancer are more likely to be diagnosed with advanced disease and are less likely to survive the disease than white women.

15 Jun 2004

Biologist has identified gene patterns that characterize a biologically distinct subtype of estrogen receptor negative breast tumor

University of North Carolina molecular biologist Charles Perou has identified the pattern of genes that characterize a biologically distinct subtype of estrogen receptor negative breast tumor.

14 Jun 2004

Receptor News and Research

New leads for the discovery of anthrax antitoxins that could be used in conjunction with antibiotics to treat late-stage anthrax

New guidelines for treating heart attacks

New imaging agent will enable doctors to rapidly and accurately detect those hard-to-diagnose appendicitis cases

New compound, ZK-CDK combines the inhibition of tumour cell growth as well as inhibition of tumour angiogenesis in one single molecule

Research points to a possible way to design anthrax toxin molecules that selectively attack tumor cells

ASU and Mayo Clinic collaborate on a new joint nursing program

New drug application for cilansetron, an investigational product for the treatment of irritable bowel syndrome

Exelixis files new drug application for a proprietary novel anticancer compound

Scientists use genetic engineering to work out how odors are encoded

European Commission has approved the use of Herceptin® (trastuzumab) in combination with Taxotere®

Drug for multiple sclerosis prevented disease development when tested on animal models

Valsartan may reduce cardiac illness and death

Harmless virus known as GBV-C slows the progression of HIV

Further evidence that a class of drugs that lower blood pressure are a treatment option for older people at high cardiovascular risk

Marijuana/Cannabis causes transient schizophrenia-like symptoms

Cancer drug gefitinib (Iressa) may be able to restore tamoxifen's anticancer activity

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

What causes polycystic ovary syndrome?

African-American women less likely to survive breast cancer than white women

Biologist has identified gene patterns that characterize a biologically distinct subtype of estrogen receptor negative breast tumor

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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