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Nicotine reduces levodopa-induced dyskinesias

The Parkinson's Institute and Clinical Center today announced research showing that intermittent nicotine treatment reduces medication-induced dyskinesias by as much as 50 percent in models of Parkinson's disease.

24 Oct 2007

Cannabis reduces pain only within a narrow dose range

Although smoking "moderate" doses of cannabis helps reduce pain in healthy research volunteers, pain is actually increased at high doses.

24 Oct 2007

Oncolytics Biotech receives approval for UK clinical trial of of REOLYSIN

Oncolytics Biotech Inc. has announced that it has received a letter of approval from the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a clinical trial using intravenous administration of REOLYSIN in combination with cyclophosphamide, a chemotherapeutic agent as well as immune modulator, in patients with advanced cancers.

24 Oct 2007

Cognitive performance in long-term abstinent elderly alcoholics

In a new study comparing elderly abstinent alcoholics with light- or nondrinking peers, the recovering alcoholics generally demonstrated equal or superior cognitive functioning to those who were not alcoholic.

24 Oct 2007

The financial burdens of overweight and obesity among elderly Americans

What many Americans eat and how little they exercise could wind up costing them - and American taxpayers - some serious money. Moreover, the overweight and obese may lose months from their lifespans.

24 Oct 2007

Purer medicines

Dutch researcher Roelof Mol has investigated possibilities for more accurately determining the composition of medicines.

24 Oct 2007

Amazon jungle plant compound blocks tissue destruction

Scientists at Case Western Reserve University's School of Medicine have published in the Journal of Inflammation a remarkable discovery with a natural product derived from the Amazon rainforest.

24 Oct 2007

New type of biodegradable nanoparticle for drug delivery

The spherical structures can encapsulate various fat-soluble medicines, which makes it easier to target tumour tissue. These nanoballs are highly promising carriers for the controlled release of anticancer drugs. Rijcken recently gained her doctorate for this research from Utrecht University.

24 Oct 2007

Public access policy for NIH-funded research set to become law

The U.S. Senate last night approved the FY2008 Labor, HHS, and Education Appropriations Bill (S.1710), including a provision that directs the National Institutes of Health (NIH) to strengthen its Public Access Policy by requiring rather than requesting participation by researchers.

24 Oct 2007

Johns Hopkins details scientific breakthroughs in malaria prevention and treatment

"Breaking the Cycle" chronicles five years of scientific discovery conducted by researchers at the Johns Hopkins Malaria Research Institute (JHMRI).

24 Oct 2007

HIV combination antiretroviral drug therapy key to saving the lives of African children

Letting nurses and other trained health care workers deliver that therapy and monitor patients, especially when doctors are in short supply, is just as important to saving lives, according to a new study by the University of Alabama at Birmingham (UAB).

24 Oct 2007

Potential new ways to treat ulcers

The alarming truth is more than 14.5 million people suffer from ulcers worldwide due to factors such as stress and the use of non-steroidal anti-inflammatory drugs (NSAIDS).

24 Oct 2007

Increased intestinal permeability by exogenous sphingomyelinase

Many signaling molecules involved in the pathogenesis of IBD, such as TNF or IFN, infections with bacteria or viruses and ionizing radiation, may cause an alteration of the lipid composition in the cell membrane by activation of sphingomyelinases (SMases).

24 Oct 2007

Traditional perception of alcoholism and impulsive behaviour may need to be reconsidered

Impulsivity is a problem common to many different personality and psychiatric disorders, including alcoholism.

24 Oct 2007

How Rhesus Macaques and Humans have conquered the world

When it comes to their social behavior, people sometimes act like monkeys, or more specifically, like rhesus macaques, a type of monkey that shares with humans strong tendencies for nepotism and political maneuvering, according to research by Dario Maestripieri, an expert on primate behavior and an Associate Professor in Comparative Human Development and Evolutionary Biology at the University of Chicago.

24 Oct 2007

Anticoagulant bivalirudin following angioplasty in heart attack patients reduces adverse events and bleeding

Late-breaking data presented at TCT 2007, the scientific symposium of the Cardiovascular Research Foundation (CRF), show that the use of the anticoagulant bivalirudin following angioplasty in heart attack patients reduces net adverse clinical events by 24 percent compared to the standard treatment, and significantly reduces major bleeding that occurs after angioplasty by 40 percent.

24 Oct 2007

Novel and inexpensive tool for identifying early signs of schizophrenia

A tendency to extract messages from meaningless noise could be an early sign of schizophrenia, according to a study by Yale School of Medicine researchers.

24 Oct 2007

Sounds can alter how masculine or feminine a person looks

Think about the confused feelings that occur when you meet someone whose tone of voice doesn't seem to quite fit with his or her gender.

24 Oct 2007

Most parents ignorant to teenager's substance use

New research results from the University at Buffalo's Research Institute on Addictions (RIA) suggest that most parents are aware of and accurately evaluate the extent of their teenager's cigarette smoking, marijuana use, drinking and overall substance use.

24 Oct 2007

Genetics of alcoholism

While both environmental and genetic factors contribute to the risk of developing alcohol dependence, it is believed to be a largely heritable – 52 to 64 percent – disease.

24 Oct 2007