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Altor receives NHLBI SBIR grant to complete ALT-836 second Phase 2 trial in ALI/ARDS

Altor BioScience Corporation announced today that the National Heart Lung and Blood Institute has awarded Altor a Small Business Innovation Research Phase II Competing Renewal Grant. The award of over $3.18 MM over three years will support Altor's efforts to complete a second Phase 2 clinical trial using ALT-836, an antibody-based tissue factor antagonist, as a therapy to treat patients with infection-induced acute lung injury/acute respiratory distress syndrome.

24 May 2011

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. Diabetic nephropathy is the foremost cause of kidney failure.

24 May 2011

Skagit Valley Hospital joins Premier healthcare alliance and saves more than $1M annually

Skagit Valley Hospital of Mount Vernon, Wash., saved more than $1 million by joining the Premier healthcare alliance.

24 May 2011

BMI increase between pregnancies linked to increased risk of gestational diabetes mellitus

Compared with women whose weight remained stable, body mass index gains between the first and second pregnancy were associated with an increased risk of gestational diabetes mellitus in the second pregnancy.

24 May 2011

Women find happy guys less sexually attractive than swaggering, brooding men: Study

Women find happy guys significantly less sexually attractive than swaggering or brooding men, according to a new University of British Columbia study that helps to explain the enduring allure of "bad boys" and other iconic gender types.

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

IPS examines subsidized malaria drugs in Kenya

Inter Press Service looks at the roll out of the Affordable Medicines Facility-malaria in Kenya. The program, which is managed by the Global Fund to Fight AIDS, Tuberculosis and Malaria, makes subsidized malaria medications available through private pharmacies in seven other pilot countries - Cambodia, Ghana, Madagascar, Niger, Nigeria, Tanzania and Uganda.

24 May 2011

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders, suggests a study led by Vanderbilt University Medical Center researcher Fang Yan, M.D., Ph.D.

24 May 2011

Variant of obesity gene may increase breast cancer risk

New research aimed to better identify the genetic factors that lead to breast cancer has uncovered a link between the fat mass and obesity associated gene and a higher incidence of breast cancer.

24 May 2011

Pakistani province cancels six U.S. aid agreements

The Pakistani province of Punjab will stop accepting U.S. aid and has canceled six agreements with the U.S. pertaining to health, education and solid waste management, according to Shahbaz Sharif, chief minister of the province, Inter Press Service reports. "Sharif has vowed to 'break the begging bowl' which he said undermines Pakistan's sovereignty," the news service writes.

24 May 2011

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment of human sarcomas. The research is published in the current issue of the journal Cancer Cell.

24 May 2011

HIV prevention study results raise public health questions about forcing patients into treatment

A New York Times "Week In Review" article examines how the results of a recent study showing combination antiretroviral therapy can reduce the risk of HIV transmission by 96 percent "reopens old questions" about the rightsof patients to refuse therapy and whether doctors, in the interest of public health, should force patients to start treatment.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

'Survival protein' protects brain against effects of stroke

Johns Hopkins scientists say that a newly discovered "survival protein" protects the brain against the effects of stroke in rodent brain tissue by interfering with a particular kind of cell death that's also implicated in complications from diabetes and heart attack.

24 May 2011

NIH awards $3.03 million grant to UTMB researcher to continue groundbreaking aging study

Rebeca Wong, one of the nation's foremost experts on aging, has been awarded $3.03 million by the National Institute on Aging of the National Institutes of Health to continue a groundbreaking study in Mexico. Wong will use the grant for a longitudinal aging study she and collaborators started in 2001.

24 May 2011

Long-term, regular acetaminophen use may be associated with lower prostate cancer risk

A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38% lower risk of prostate cancer. The study appears in Cancer Epidemiology, Biomarkers and Prevention and is one of only two studies of prostate cancer to date that have examined the association with acetaminophen use that was both long-term and regular.

24 May 2011

African-Americans with multiple sclerosis have lower vitamin D levels

African-Americans who have multiple sclerosis have lower vitamin D levels than African-Americans who don't have the disease, according to a study published in the May 24, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

24 May 2011

Vertex Incivek receives FDA approval for treatment of chronic hepatitis C

The U.S. Food and Drug Administration today approved Incivek treat certain adults with chronic hepatitis C infection. Incivek is used for patients who have either not received interferon-based drug therapy for their infection or who have not responded adequately to prior therapies. Incivek is approved for use with interferon therapy made up of peginterferon alfa and ribavirin.

24 May 2011

Opinion: Recognizing the success of foreign aid

In the Wall Street Journal, Bill Gates, co-chair of the Bill & Melinda Gates Foundation, applauds economist Charles Kenny's book, "Getting Better: Why Global Development Is Succeeding - and How We Can Improve the World Even More."

24 May 2011

New genetic testing technology for IVG embryos

Researchers at the Johns Hopkins University School of Medicine have devised a new technique, which helps couples that are affected by or are carriers of genetic diseases have in vitro fertilized babies free of both the disease in question and other chromosomal abnormalities. The results were reported in the April issue of Fertility and Sterility.

23 May 2011

Research News and Research

Altor receives NHLBI SBIR grant to complete ALT-836 second Phase 2 trial in ALI/ARDS

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

Skagit Valley Hospital joins Premier healthcare alliance and saves more than $1M annually

BMI increase between pregnancies linked to increased risk of gestational diabetes mellitus

Women find happy guys less sexually attractive than swaggering, brooding men: Study

Novel hepatitis C-like virus discovered in dogs

IPS examines subsidized malaria drugs in Kenya

Probiotic bacterial protein could offer new oral therapeutic option for inflammatory bowel disorders

Variant of obesity gene may increase breast cancer risk

Pakistani province cancels six U.S. aid agreements

Mount Sinai researchers identify protein signaling hyperactivity in human sarcoma cells

HIV prevention study results raise public health questions about forcing patients into treatment

Scientists discover genetic regions that affect severity of cystic fibrosis

'Survival protein' protects brain against effects of stroke

NIH awards $3.03 million grant to UTMB researcher to continue groundbreaking aging study

Long-term, regular acetaminophen use may be associated with lower prostate cancer risk

African-Americans with multiple sclerosis have lower vitamin D levels

Vertex Incivek receives FDA approval for treatment of chronic hepatitis C

Opinion: Recognizing the success of foreign aid

New genetic testing technology for IVG embryos

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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