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Indian drugmaker seeks to make, sell generic version of Pfizer's HIV drug

The Indian drugmaker Natco Pharma "said Wednesday it has informed Pfizer Inc. that it wants to make and sell a low-cost generic version of the U.S. company's [drug] maraviroc for treating the HIV infection under a so-called 'compulsory license'," Dow Jones Newswires/Smart Money reports.

6 Jan 2011

Mutated TDP-43 can cause neurons to die: Study

Lou Gehrig's disease, or amyotrophic lateral sclerosis, and frontotemporal lobar degeneration are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps.

6 Jan 2011

Sanofi-aventis announces publication of positive BSI-201 phase II results for breast cancer

Sanofi-aventis and its wholly-owned subsidiary, BiPar Sciences, today announced that The New England Journal of Medicine published the final phase II data for the investigational drug iniparib demonstrating significant clinical benefit in women with metastatic triple negative breast cancer when iniparib was administered in combination with chemotherapy agents gemcitabine/carboplatin.

6 Jan 2011

Scientists identify prognostic biomarker to treat patients with HCV

Scientists at Inserm and Institut Pasteur have performed biomarker discovery on patients being treated for chronic hepatitis C infection. Their work, published in The Journal of Clinical Investigation, demonstrates that the plasma levels of the protein IP-10 predict, prior to treatment initiation, the efficacy of treatment with pegylated-interferon and ribavirin.

6 Jan 2011

Research says regular intake of green tea can prevent Alzheimer's disease

Regularly drinking green tea could protect the brain against developing Alzheimer's and other forms of dementia, according to latest research by scientists at Newcastle University.

6 Jan 2011

States continue implementation efforts; Some newly-elected AGs step up legal attacks

Even as health overhaul drama continues on Capitol Hill, news outlets continue to watch how developments at the state level will impact the law's implementation.

6 Jan 2011

Regular eye exams are critical to prevent glaucoma

Glaucoma is the second leading cause of blindness, may strike without symptoms, is not preventable, but it is treatable. During National Glaucoma Awareness Month, The Minnesota Optometric Association (MOA) urges regular eye exams because early detection and treatment is critical to maintain healthy vision and protect the eyes from the effects of glaucoma and other potentially blinding diseases.

6 Jan 2011

Columbia research team identifies bacteria may play a key role in atherosclerosis

Dr. Emil Kozarov and a team of researchers at the Columbia University College of Dental Medicine have identified specific bacteria that may have a key role in vascular pathogenesis, specifically atherosclerosis, or what is commonly referred to as "hardening of the arteries" - the number one cause of death in the United States.

6 Jan 2011

Positive topline results from ZGN-433 Phase 1b study in obesity patients

Zafgen, a pharmaceutical company pioneering novel obesity therapeutics to help the body regain and sustain a lean, healthy state by targeting imbalances in fat metabolism, today announced positive topline results from its Phase 1b study of ZGN-433, a methionine aminopeptidase 2 inhibitor, for the treatment of severe obesity.

6 Jan 2011

Study shows positive effects of formal child care in improving language skills

Fewer children who attend regular formal centre- and family-based child care at 1.5 years and 3 years of age were late talkers compared with children who are looked after at home by a parent, child-carer or in an outdoor nursery. This is shown in a new study by the Norwegian Institute of Public Health of nearly 20,000 children.

6 Jan 2011

IV fluids for trauma patients may not be life savers all the time

Severely injured patients who are routinely given IV fluids by paramedics before transport to the nearest trauma center are significantly more likely to die than similarly injured patients who don't get the time-consuming IV treatment before hospitalization, new Johns Hopkins-led research suggests.

6 Jan 2011

State roundup: Minn. Medicaid expansion, Mass. health costs, Calif. free clinic

[Gov.] Dayton is scheduled to sign an executive order that would expand Medicaid coverage in Minnesota -- a move Republicans in the Legislature oppose. Dayton's decision won't put an end to the debate (Scheck, 1/5).

6 Jan 2011

Cardiologists identify blood protein fragment that can predict heart attack

Cardiologists at the University of Connecticut Health Center have identified a protein fragment that when detected in the blood can be a predictor of heart attack.

6 Jan 2011

Researchers regenerate complete shoulder joint surfaces using patient's own cells

Artificial joint replacements can drastically change a patient's quality of life. Painful, arthritic knees, shoulders and hips can be replaced with state-of-the-art metal or ceramic implants, eliminating pain and giving a person a new lease on life.

6 Jan 2011

Study provides new insights into how viruses establish chronic infections

Walter and Eliza Hall Institute researchers in Melbourne, Australia, have discovered how a key viral gene helps viruses evade early detection by the immune system. Their finding is providing new insights into how viruses are able to establish chronic infections, leading scientists to reevaluate their approaches to viral vaccine development.

6 Jan 2011

OpEds: Sebelius, Fla. Attorney General, USA Today, Wash Post opine about repeal strategies

Over the past nine months, I've traveled around the country and seen the benefits of this law firsthand. Unless we want to take coverage away from cancer patients, reduce oversight for insurance companies, raise prescription drug costs for seniors, weaken Medicare, add $1 trillion to the deficit and undo dozens of other reforms that are improving health around the country, we can't afford repeal (Kathleen Sebelius, 1/5).

6 Jan 2011

Transposagen, CDI enter license agreement for iPS cell line production

Transposagen Biopharmaceuticals, a leader in genetic modification technology, announced today that it has entered into a non-exclusive license agreement with Cellular Dynamics International, the world's largest producer of human induced pluripotent stem cell lines and tissue cells for drug discovery and safety.

6 Jan 2011

Study explores 26 school-based nutrition interventions in the US

Thanks to the Let's Move initiative, society is becoming more aware of alarming statistics like 1 in 4 children are obese and childhood obesity has nearly doubled over the past two decades! With this platform, nutrition education and physical activity in the classroom have taken the forefront against this growing epidemic. A study in the January/February 2011 issue of the Journal of Nutrition Education and Behavior explores twenty-six school-based nutrition interventions in the United States.

6 Jan 2011

Outlook continues to be negative for insurers, modern healthcare reports

Health insurers' outlook continues to be negative as the sector faces new regulations, heightened political pressure and a weak economy, which are expected to squeeze earnings, one major ratings agency said (Evans, 1/4).

6 Jan 2011

Mayo Clinic researchers estimate lifetime risk of developing rheumatoid arthritis in men and women

Mayo Clinic researchers have determined the lifetime risk of developing rheumatoid arthritis and six other autoimmune rheumatic diseases for both men and women. The findings appear online in Arthritis and Rheumatism.

6 Jan 2011