Retinopathy of Prematurity News and Research

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Cerebral damage, ROP may increase risk of visual impairment in extremely preterm children

Cerebral damage and retinopathy of prematurity appear to be independently associated with visual impairment among preschool children who were born extremely premature, according to a report published Online First by Archives of Ophthalmology, a JAMA Network publication.

13 Jun 2012

RPB awards $220,000 to SUNY Downstate for eye research

Capping SUNY Downstate Medical Center's growth into a major center for eye research, Research to Prevent Blindness (RPB) has awarded SUNY Downstate a four-year challenge grant of $220,000 to spur the development of advanced research into the causes, treatment, and prevention of blinding diseases. Douglas R. Lazzaro, MD, professor and chair of ophthalmology, is the principal investigator.

24 Jan 2012

NIH grants support SUNY's neuroscience, pediatric pharmacology and vision research

The State University of New York has received two grants totaling more than $4.3 million from the National Institutes of Health (NIH) to support neuroscience and pediatric pharmacology and vision research as part of SUNY REACH, a collaborative research network of SUNY's four academic health centers and the College of Optometry.

15 Oct 2011

DMEI dedicates new $46M research and clinical facility

Officials from the Dean McGee Eye Institute today announced the dedication of the Institute's new $46 million, five-story, 78,000-square-foot, world-class research and clinical facility.

1 Oct 2011

Queen's University scientists partner to treat premature baby blindness with stem cells

Scientists from the School of Medicine, Dentistry and Biomedical Sciences at Queen's University Belfast are teaming up to develop a cure to an illness that can lead to blindness in premature babies, thanks to funding from children's charity Action Medical Research.

18 May 2011

Inexpensive drug therapy shows promise in treating premature infants with childhood blindness

A readily available, inexpensive drug therapy showed a significant benefit in treating premature infants with the worst and historically most difficult-to-treat cases of retinopathy of prematurity.

17 Feb 2011

12-HETE enzyme inhibition can prevent ischemic retinopathy: Study

The inhibition or removal of an enzyme may prevent or treat ischemic retinopathy by stalling growth of unwanted vessels in the retina, Medical College of Georgia researchers say.

14 Jan 2011

New study on Retinopathy of Prematurity

A new clinical trial at The Children's Hospital at OU Medical Center will focus on ways to catch a debilitating eye disease before it's too late.

18 Oct 2010

Childrens Hospital Los Angeles receives $1M NCI grant for eye port clinical trial to treat retinoblastoma in children

The Vision Center at Childrens Hospital Los Angeles has been awarded a $1 million grant from the National Cancer Institute (NCI) to conduct a clinical trial on a new drug delivery system to treat young children diagnosed with retinoblastoma. The device is designed to deliver chemotherapy through a tiny silicone cup sealed to the outer surface (sclera) of the eye, which can more directly target cancer cells and greatly reduce the side effects caused by current chemotherapy treatments.

14 Oct 2010

Feeding infants before examination for retinopathy of prematurity reduces stress

Premature infants are often examined for retinopathy of prematurity (ROP). This exam can be quite stressful for the neonate, causing changes in heart rate, blood pressure and oxygen saturation, and increased crying. In a recent study published in the Journal of AAPOS, the Official Publication of the American Association of Pediatric Ophthalmology and Strabismus, researchers found that feeding infants one hour before the examination unexpectedly reduced stress but did not increase vomiting or gastric aspirates.

30 Sep 2010

Scientific paper explains impact of visual cycle modulation in neurovascular retinopathy

Acucela, a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, announced today that a scientific paper co-authored by Ryo Kubota, M.D., Ph.D., chairman, president and chief executive officer of Acucela, has been published in Experimental Eye Research. The paper, "Visual Cycle Modulation in Neurovascular Retinopathy" was also co-authored by scientists from Children's Hospital and Harvard Medical School in Boston and demonstrates for the first time the impact of treatment with a visual cycle modulator (VCM) on retinopathy in an immature eye.

10 Aug 2010

Benefits of childhood screening for vision disorders in preschool children

In his article in the current issue of Deutsches -rzteblatt International (Dtsch Arztebl Int 2010; 107[28-29]: 495-9), Wolf A. Lagr-ze examines whether or not childhood screening for vision disorders in preschool children is worthwhile.

5 Aug 2010

CPAP treatment may be a better option for preterm infants

A national study involving a UT Southwestern Medical Center neonatologist provides new insight into how much oxygen preterm infants should receive as well as the optimal way to deliver it to them.

3 Jun 2010

Early CPAP as effective for preemies as ventilator, with fewer complications: Study

Two findings from an NIH research network study provide new information on how much oxygen very preterm infants should receive starting on the first day of life and the most effective means to deliver it to them.

17 May 2010

Early treatment of ROP for high-risk premature babies can improve vision: ETROP study

Scientists have shown that through eye examinations, doctors can identify infants who are most likely to benefit from early treatment for a potentially blinding eye condition called retinopathy of prematurity, resulting in better vision for many children.

4 May 2010

Tools and applications of QI methodology in Neonatal-Perinatal practice

The March 2010 issue of Clinics in Perinatology, published by Elsevier, provides Neonatologists and Maternal-Fetal-Medicine specialists with the tools and concepts necessary to understand Quality Improvement (QI) methodology and to initiate QI projects within their own practices and neonatal intensive care units (NICUs).

17 Apr 2010

Handheld SD-OCT device helps examine vitreoretinal interface in infants with SBS

Ophthalmologists examining infants for possible Shaken Baby Syndrome (SBS) found that a handheld Spectral Domain Optical Coherence Tomography (SD-OCT) device provided high-resolution images of the retina and the vitreoretinal interface in infants with SBS, reports a study in the current issue of Retina, The Journal of Retinal and Vitreous Diseases.

17 Apr 2010

Comprehensive development strategy yields two potential drugs that block cancer-promoting pathways

A comprehensive drug development strategy that starts with extensive screening of potential targeting agents and then narrows down to a small-molecule prototype has yielded two potential drugs that block cancer-promoting pathways in novel ways, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in two papers published back-to-back online at the Proceedings of the National Academies of Science.

26 Feb 2010

New hand-held device eliminates technical challenges involved in imaging progressive ROP in infants

Using a hand-held spectral domain optical coherence tomography (SD-OCT) imaging device, researchers have obtained high-resolution retinal scans of premature infants with progressive retinopathy of prematurity (ROP), according to a report in this month's Archives of Ophthalmology.

12 Jan 2010

Contact lens can produce near-normal vision in infants and children

Infants as young as one-month-old are prescribed contact lenses at pediatric eye surgery centers so their visual system will develop correctly. Infants may be fitted for contacts if they have had cataract surgery, need extremely high-strength prescription glasses, or have very different prescriptions for the two eyes.

22 Dec 2009