Rheumatism News and Research

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Rheumatism is a group of disorders marked by inflammation or pain in the connective tissue structures of the body. These structures include bone, cartilage, and fat.

Genetic risk for early death in rheumatoid arthritis

A chronic autoimmune disease, rheumatoid arthritis (RA) is marked by inflammation that takes a progressive toll on not only the joints, but also various organs and the whole body.

30 Apr 2007

Arthritis pain processed in parts of brain concerned with emotions and fear

Researchers at The University of Manchester have discovered that arthritis pain, unlike that induced as part of an experiment, is processed in the parts of the brain concerned with emotions and fear.

From The University of Manchester 30 Mar 2007

Role of emotions in how patients feel arthritis pain

How does the brain process the experience of pain? Thanks to advances in neuroimaging, we now know the answer lies in a network of brain structures called the pain matrix.

30 Mar 2007

Decoy receptor 3 expressed in rheumatic synovial fibroblasts protects the cells against Fas-induced apoptosis

A complex autoimmune disease, rheumatoid arthritis (RA) is characterized by chronic inflammation and progressive joint damage. This process begins with hyperplasia, or excessive increase in size and thickness, of synovial tissue. Along with provoking cartilage and bone destruction, this abnormal tissue growth is resistant to apoptosis, the natural cell death vital to the generation of healthy new cells.

30 Mar 2007

Depression linked with a specific autoantibody and central nervous system dysfunction in lupus

Systemic lupus erythomatosus (SLE), often simply called lupus, is a complex autoimmune disease marked by joint pain, skin rashes, extreme fatigue, and depression, among other symptoms.

27 Feb 2007

Influence of inflammatory polyarthritis on cancer incidence and survival

Patients with rheumatoid arthritis (RA), a chronic inflammatory autoimmune disease, have a high risk of death from disease - at least double the risk of the general population, studies overwhelmingly show. Evidence has been less clear on whether RA patients are exceptionally vulnerable to dying from cancer.

27 Feb 2007

New method of predicting rheumatoid arthritis offers early help to sufferers

Dutch researchers believe they may have come up with a new way of predicting whether patients with arthritic symptoms will progress to the autoimmune form of the disease, rheumatoid arthritis.

31 Jan 2007

A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis

Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis (RA) is a painful and potentially disabling autoimmune disease.

30 Jan 2007

Gums produce substances that lead to degeneration of the jawbone

Our gums' own cells produce the substances that lead to the degeneration of the jawbone. This is one of the findings in a dissertation that Py Palmqvist defended at Umea University in Sweden recently.

24 Jan 2007

Acupuncture and Turmeric could be viable treatment options for arthritis sufferers

People who suffer from osteoarthritis (OA) as a rule find it has to varying degrees an impact on their mobility and quality of life.

31 Oct 2006

Acupuncture in patients with osteoarthritis of the knee or hip

Osteoarthritis (OA) has a major impact on patients' mobility and quality of life but the anti-inflammatory drugs used to treat it are associated with a number of side effects.

30 Oct 2006

Turmeric for prevention of rheumatoid arthritis and osteoporosis

An ancient spice, long used in traditional Asian medicine, may hold promise for the prevention of both rheumatoid arthritis and osteoporosis, according to a recently completed study at The University of Arizona College of Medicine.

30 Oct 2006

New cell-based targets for treating autoimmune inflammatory diseases

Patients with systemic autoimmune diseases such as lupus and rheumatoid arthritis (RA) often suffer loss of kidney function.

31 Aug 2006

Tumor necrosis factor A antagonist use and cancer in patients with rheumatoid arthritis

Patients with rheumatoid arthritis (RA), an autoimmune, inflammatory disease marked by progressive joint and organ damage, face a high risk of developing cancer.

31 Aug 2006

Gout is a significant independent risk factor of heart attack

First study to show that among men with no previous history of coronary artery disease, gout is a significant independent risk factor of heart attack.

2 Aug 2006

Reduced levels of antiinflammatory cytokines in patients with chronic widespread pain

Chronic widespread pain, a common medical condition, can be difficult to treat and is often associated with fatigue, poor sleep and depression.

26 Jul 2006

Estradiol and its metabolites and their association with knee osteoarthritis

Osteoarthritis, which usually develops between the ages of 40 and 50, is more prevalent in women. It is thought that sex hormones may play a role in developing the disease, since they can be involved in inflammation of the tissues affected by it.

26 Jul 2006

Disease-specific gene expression profiles in patients with rheumatoid arthritis

They sleep together, eat together, and most people find it impossible to tell them apart. Identical twins who grow up together share just about everything, including their genes.

26 Jul 2006

Rituximab shown to significantly inhibit structural damage of joints caused by rheumatoid arthritis

New data presented at the EULAR meeting (European League Against Rheumatism) show for the first time that MabThera (rituximab), a unique B cell targeted therapy, is able to significantly inhibit structural damage of joints caused by rheumatoid arthritis (RA).

27 Jun 2006