Ribonucleic Acid News and Research

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Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

Researchers investigated the efficacy of monovalent mRNA COVID-19 vaccines in immunocompromised adults during the Omicron dominance period starting December 2021.

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

In a recent study published in the New England Journal of Medicine, researchers presented the findings of the ongoing KidCOVE trial in the United States (US).

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

How does COVID-19 and its treatment affect testicular function?

Researchers summarized available information related to the reproductive effects of COVID-19 in men.

23 Oct 2022

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

Researchers investigated the association between two or three doses of the messenger ribonucleic acid (mRNA) COVID-19 vaccine and viral loads and symptoms during infections with different SARS-CoV-2 variants.

23 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Researchers conducted a nationwide study in Denmark to assess the public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2.

22 Oct 2022

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Researchers performed retrospective detection of the monkeypox virus in the testes of nonhuman primates.

22 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

In a recent study posted to the medRxiv* preprint server, University of Arizona researchers assessed the relationship between antibody responses and analgesic usage after coronavirus disease 2019 (COVID-19) vaccination.

20 Oct 2022

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

In a recent study published in the journal eLife, researchers showed the utility of machine-learning models in identifying early immune signatures, which could reliably predict clinical and immunological outcomes in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected outpatients.

20 Oct 2022

Ribonucleic Acid News and Research

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

A novel approach for viral genomic surveillance

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

A study of Moderna's COVID vaccine in children aged 6 months to 5 years

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

How does COVID-19 and its treatment affect testicular function?

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Monkeypox virus infection and its persistence in the testes of infected crab-eating macaques

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Analgesic use after COVID-19 vaccination does not negatively affect antibody responses

Multiomics analysis identifies immunobiomarkers for COVID-19 severity in outpatients

Are pediatric COVID-19 samples less infectious?

Study shows low risk of myocarditis/pericarditis after mRNA COVID-19 vaccination

Impaired SARS-CoV-2 neutralization after booster vaccination in the elderly

SARS-CoV-2 placentitis may cause placental destruction and stillbirth in women not vaccinated for COVID-19

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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