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Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Bivalent COVID-19 boosters offer stronger protection for seniors, Australian study reveals

Study compares the effectiveness of bivalent and monovalent booster vaccines against COVID-19 mortality in individuals aged 65 and older. It finds that bivalent boosters show higher vaccine effectiveness against COVID-19 mortality, particularly for the Omicron variant, compared to monovalent vaccines.

27 Nov 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

Multi-ingredient herbal supplement boosts cognitive speed and gut health in seniors

In a study on elderly patients with subjective memory decline, a 90-day herbal supplement regimen improved cognitive task speed and altered gut microbiota, despite causing memory deficits. This intervention increased urinary tyrosine levels, suggesting a dopaminergic activity role in cognitive enhancements.

26 Nov 2023

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

Researchers reviewed existing data on the bio-modulatory effects of pomegranate (Punica granatum l., PG) polyphenols on metabolic disorders.

24 Nov 2023

New insights into how SARS-CoV-2 evades our immune system

This review in Cellular and Molecular Immunology delves into the innate immune response to SARS-CoV-2, exploring how the virus evades immunity and the potential role of innate immunity in long-COVID and vaccine responses, shedding light on future therapeutic strategies.

23 Nov 2023

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

Researchers used integrative metaproteogenomic analysis to show that changes in salivary microbiota and biomolecules can indicate cognitive impairment stages in Parkinson’s disease patients, offering a potential diagnostic tool.

23 Nov 2023

New study shows bivalent COVID-19 booster increases antibody response in lung cancer patients

Bivalent booster dose enhanced neutralization of Omicron XBB (sub)variants in non-small cell lung cancer (NSCLC) patients.

23 Nov 2023

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Study highlights the spread of the highly pathogenic avian influenza A (H5N1) virus among non-domesticated animals in the U.S., revealing neurological symptoms as a key clinical presentation and expanding the range of species affected by this Eurasian lineage virus.

19 Nov 2023

Pigeon virus causes fatal neurological disease in young leukemia patient

A case report details a fatal neurologic disease in an immunocompromised toddler caused by pigeon avian paramyxovirus, underscoring the effectiveness of metagenomic testing in diagnosing complex infectious diseases.

19 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

Placental inflammation's role in adult depression and heart disease

An expression signature related to inflammation expressed in Hofbauer cells in the placenta, calculating polygenic risk scores to predict its expression.

14 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

The role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB).

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Ribonucleic Acid News and Research

Genetic mutation in OXR1 gene linked to brain development issues

Bivalent COVID-19 boosters offer stronger protection for seniors, Australian study reveals

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Multi-ingredient herbal supplement boosts cognitive speed and gut health in seniors

Pomegranate's power: Studies show promise in cardiovascular and diabetic health

New insights into how SARS-CoV-2 evades our immune system

Saliva analysis breakthrough: Detecting cognitive decline stages in Parkinson’s patients

New study shows bivalent COVID-19 booster increases antibody response in lung cancer patients

Avian influenza A H5N1 virus impacts wide range of wildlife in the U.S., study shows

Pigeon virus causes fatal neurological disease in young leukemia patient

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

New research explores the unique effects of ADHD medications on Drosophila brain cells

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Placental inflammation's role in adult depression and heart disease

Pioneering study finds predictive biomarker in lung adenocarcinoma

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis use alters DNA methylation, with implications beyond smoking effects

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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