Ribosome News and Research

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Second-generation antibiotic shows promise against common bacterial infections

Researchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness against common bacterial infections that pose a serious health threat to children and adults.

21 May 2015

Researchers study early response of cells to ischemia

A group of researchers from the Lomonosov Moscow State University in collaboration with their Irish colleagues from the University College Cork has studied the early response of cells to ischemia, which is a restriction in blood supply to tissues causing the death of the cell.

6 May 2015

RNA could be a potential target for new anticancer drugs, say UC Berkeley scientists

Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA intermediaries between DNA and proteins.

7 Apr 2015

Scientists identify how mRNA deciphers critical information within genetic code

Case Western Reserve scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators' findings, which appear in the March 12 journal Cell, give scientists critical new information in determining how best to engage cells to treat illness — and, ultimately, keep them from emerging in the first place.

18 Mar 2015

TSRI scientists confirm ribosome assembly as new target for anti-cancer drugs

Ribosomes, ancient molecular machines that produce proteins in cells, are required for cell growth in all organisms, accomplishing strikingly complex tasks with apparent ease. But defects in the assembly process and its regulation can lead to serious biological problems, including cancer.

17 Mar 2015

NTU Singapore setting up new institute to find cures for human diseases

Nanyang Technological University is setting up a new institute to advance research in the life sciences, with a focus on ramping up Singapore's efforts in finding cures for human diseases.

16 Feb 2015

Recipients of The 2015 Protein Society Awards announced

The Protein Society, the premiere international society dedicated to supporting protein research, announces the winners of The 2015 Protein Society Awards. The awards will be conferred at the 29th Annual Symposium of The Protein Society (July 22-25, 2015, Barcelona, Spain).

5 Feb 2015

SLU researcher discovers new information about how antibiotics stop staph infections

In research published in Proceedings of the National Academy of Sciences, assistant professor of biochemistry and molecular biology at Saint Louis University Mee-Ngan F. Yap, Ph.D., discovered new information about how antibiotics like azithromycin stop staph infections, and why staph sometimes becomes resistant to drugs.

23 Jan 2015

Modelling the biological mesoscale: an interview with Professor Art Olson

The biological mesoscale range includes biological structures that range from 10 to 100 nanometers (billionths of a meter). Structures in this size range include viruses, cellular organelles, large molecular complexes, and any other internal cellular environments within that range.

18 Jan 2015

Antibiotic for infections comes from good bacteria found in turkeys

While the turkey you eat on Thursday will bring your stomach happiness and could probably kick-start an afternoon nap, it may also save your life one day.

26 Nov 2014

Research on zebrafish helps identify cause of unknown genetic disorder

Research in zebrafish has helped identify the cause of an unknown genetic disorder affecting a boy and two of his uncles, scientists report in an article published October 14 in the journal GENETICS.

16 Oct 2014

Anticonvulsant drug may help develop new class of antibiotics

McMaster scientists have found that an anticonvulsant drug may help in developing a new class of antibiotics.

23 Sep 2014

Researchers reveal new approaches for antimalarial drug development

Melbourne researchers are making progress towards new antimalarial drugs, after revealing how an antibiotic called emetine blocks the molecular machinery that produces the proteins required for malaria parasite survival.

4 Sep 2014

Researchers reprogram nonribosomal peptide synthetases for clickable amino acids

A single targeted mutation is enough to alter a natural peptide system so that it also incorporates non-natural amino acids into peptides, report Swiss scientists in the journal Angewandte Chemie.

13 Aug 2014

Isoform: New protein offers novel therapeutic approach for patients with DMD

Scientists have discovered a new form of dystrophin, a protein critical to normal muscle function, and identified the genetic mechanism responsible for its production.

11 Aug 2014

Biochemists report advance in production of functional mirror-image proteins

University of Utah biochemists have reported an advance in the production of functional mirror-image proteins.

29 Jul 2014

Scientists develop RNA that binds cGMP

The transmission of signals within cells is dependent on cyclic guanosine monophosphate (cGMP) as an important secondary messenger. German scientists have now developed an RNA that binds cGMP. As reported in the journal Angewandte Chemie, it is possible to suppress the cGMP signal cascade in genetically modified cells that produce this RNA.

10 Jul 2014

Alcoholic liver disease: an interview with Dr Vinood Patel, University of Westminster

Alcoholic liver disease (ALD) is one of the leading causes of death worldwide and also in the UK. As its name indicates this disease arises due to consuming excessive amounts of alcohol (80 g/day) over an extended period, normally 10-20 years.

24 Jun 2014

Discovery provides scientists with better understanding of limiting uncontrolled cell growth

Biologists at UC San Diego have found the "missing link" in the chemical system that enables animal cells to produce ribosomes-the thousands of protein "factories" contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.

24 Jun 2014

Study provides insight into genetic causes of cleft lip and cleft palate

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face.

28 May 2014