SARS CoV 2 News and Research

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Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

An experimental messenger RNA (mRNA)-based vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) elicits protective immune responses in mice and non-human primates, researchers report on July 23rd in the journal Cell.

24 Jul 2020

Seaweed extract outperforms remdesivir in inhibiting SARS-CoV-2 in cell studies

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

24 Jul 2020

Scientists discover how coronavirus enters cells without encountering immune system resistance

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

New app could help scientists to investigate the use of wearable devices for COVID-19 detection

The researchers, funded by National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre (BRC), created the Mass Science app that allows COVID-Collab study participants to connect wearables, such as Fitbit devices, and share data including heart rate, activity and sleep.

24 Jul 2020

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Researchers have shown that hydroxychloroquine interferes with only one redundant pathway that activates the SARS-CoV-2 spike protein.

24 Jul 2020

Pets show antibodies to SARS-CoV-2 in Italian study

A study shows that reverse transmission of SARS-CoV-2 is probable, with 3-4% of pets showing antibodies to the infection, though no virus was recovered.

24 Jul 2020

Scientists determine the origin and transmission rates of SARS-CoV-2 strains

A team of Brazilian and European scientists has determined the transmission rates and out-of-country origins of predominant SARS-CoV-2 strains currently circulating in Brazil, which harbors one of the fastest growing COVID-19 epidemics in the world.

24 Jul 2020

Researchers design new version of protein to develop COVID-19 vaccine

Responding to a need to quickly develop billions of doses of lifesaving COVID-19 vaccines, a scientific team at The University of Texas at Austin has successfully redesigned a key protein from the coronavirus, and the modification could enable much faster and more stable production of vaccines worldwide.

24 Jul 2020

Engineered SARS-CoV-2 spike protein is more stable and can generate larger yields in the lab

A team of scientists has engineered the spike protein of the SARS-CoV-2 virus - a critical component of potential COVID-19 vaccines - to be more environmentally stable and generate larger yields in the lab.

23 Jul 2020

Study shows molecular mechanism of SARS-CoV-2 Mpro

The Computational Biochemistry Group's research has been selected as one of the most outstanding studies of 2020 by the journal Chemical Science.

23 Jul 2020

Free SaTScan Software Rapidly Detects Emerging COVID-19 Hotspots in New York City

As an example of precision public health, a new study reports the successful detection of a potential new local COVID-19 case cluster.

23 Jul 2020

Neutralizing antibodies isolated from COVID-19 patients can quash SARS-CoV-2

Scientists across the globe are racing to study how antibodies can help suppress SARS-CoV-2, the virus that causes the coronavirus disease (COVID-19).

23 Jul 2020

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

In a new bioRxiv study, authors identified a isoform of ACE2 (designated as deltaACE2 or dACE2) receptor, shown to be induced in various human cell types.

23 Jul 2020

New article sheds light on challenges faced by vaccine developers

With the global pandemic still in full swing, scientists are working to develop a vaccine in record time. While everyone wants an effective vaccine, they don't all agree on how to get there and what "effective" really means.

23 Jul 2020

Researchers assess the damage caused by microbubbles in brain injuries

Say there's a bomb attack on a military base. A few of the soldiers suffer concussions and other brain injuries. Could some of the injuries be caused by tiny bubbles that form and collapse within the skull during head trauma?

23 Jul 2020

NIH leaders create a framework to scale up testing technologies for COVID-19

In a paper in the New England Journal of Medicine, scientific leaders from the National Institutes of Health set forth a framework to increase significantly the number, quality and type of daily tests for detecting SARS-CoV-2, the virus that causes COVID-19, and help reduce inequities for underserved populations that have been disproportionally affected by the disease.

23 Jul 2020

Study shows antibodies drop sharply in first three months after mild COVID-19 cases

A study by UCLA researchers shows that in people with mild cases of COVID-19, antibodies against SARS-CoV-2 -- the virus that causes the disease -- drop sharply over the first three months after infection, decreasing by roughly half every 73 days.

23 Jul 2020

For-profit status of LTC homes is associated with more cases of COVID-19 outbreaks, deaths

For-profit status is associated with the extent of an outbreak of coronavirus disease 2019 (COVID-19) in long-term care (LTC) homes and the number of resident deaths from COVID-19, but not the likelihood of an outbreak, which was related to the infection rate in the surrounding local public health unit and the total number of beds in the home, found new research published in CMAJ (Canadian Medical Association Journal).

23 Jul 2020

Findings could help design vaccines against coronavirus

Scientists investigating the evolution of the virus that causes Covid19 say that its mutation seems to be directed by human proteins that degrade it, but natural selection of the virus enables it to bounce back. The findings could help in the design of vaccines against the virus.

23 Jul 2020

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

Arcturus Therapeutics Holdings Inc., a leading clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines, and Duke-NUS Medical School, Singapore's flagship research-intensive graduate entry medical school, today announced that the Clinical Trial Application for COVID-19 vaccine candidate LUNAR-COV19 has been approved to proceed by the Singapore Health Sciences Authority.

22 Jul 2020

SARS CoV 2 News and Research

Experimental mRNA-based COVID-19 vaccine elicits protective immune responses in animals

Seaweed extract outperforms remdesivir in inhibiting SARS-CoV-2 in cell studies

Scientists discover how coronavirus enters cells without encountering immune system resistance

New app could help scientists to investigate the use of wearable devices for COVID-19 detection

An important SARS-CoV-2 enzyme is responsible for low in vivo antiviral efficacy of hydroxychloroquine

Pets show antibodies to SARS-CoV-2 in Italian study

Scientists determine the origin and transmission rates of SARS-CoV-2 strains

Researchers design new version of protein to develop COVID-19 vaccine

Engineered SARS-CoV-2 spike protein is more stable and can generate larger yields in the lab

Study shows molecular mechanism of SARS-CoV-2 Mpro

Free SaTScan Software Rapidly Detects Emerging COVID-19 Hotspots in New York City

Neutralizing antibodies isolated from COVID-19 patients can quash SARS-CoV-2

Study shows interferons do not induce the expression of SARS-CoV-2 cell entry receptor

New article sheds light on challenges faced by vaccine developers

Researchers assess the damage caused by microbubbles in brain injuries

NIH leaders create a framework to scale up testing technologies for COVID-19

Study shows antibodies drop sharply in first three months after mild COVID-19 cases

For-profit status of LTC homes is associated with more cases of COVID-19 outbreaks, deaths

Findings could help design vaccines against coronavirus

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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