Sample Preparation News and Research

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Femtogram-level chemical measurements now possible

Finding a simple and convenient technique that combines nanoscale structural measurements and chemical identification has been an elusive goal.

31 Mar 2008

Direct selection of human genomic loci by microarray hybridization

Researchers at Baylor College of Medicine and Roche NimbleGen Inc., a fully integrated part of Roche Applied Science, have published details of a highly efficient and cost-effective method for capturing targeted regions of the genome via NimbleChip microarrays in preparation for high-throughput 454 Sequencing.

16 Oct 2007

Portable detection system for foot-and-mouth and avian flu

Smiths Detection, part of the global technology business Smiths Group, today announces it is to launch a portable detection system that will enable veterinarians to carry out on-site diagnosis of animal diseases such as foot-and-mouth and avian flu.

15 Oct 2007

New X-ray microscope shows nanomaterials in 3D

Using a new x-ray microscope that can look at nanomaterials in three dimensions, an international research team has produced the first detailed atomic structure of a core-shell nanoparticle.

18 Dec 2006

Dual-mode nanoscale imaging yields new details of cellular events

To create drugs capable of targeting malignancies, scientists must first decode exactly how a cell or a group of cells communicates with other cells and reacts to a broad spectrum of complex biomolecules surrounding it.

21 Aug 2006

FDA develops cost-effective way to identify bioterror agents used in hoax incidents

Researchers at the Food and Drug Administration (FDA) National Center for Toxicological Research (NCTR) are developing a quick, cost-effective way to screen for and identify bioterror agents and other substances used in hoax incidents.

3 Aug 2006

New system for analyzing how drugs bind to proteins

Researchers at Florida State University's National High Magnetic Field Laboratory and Scripps Florida have developed and evaluated a robust new system for analyzing how drugs bind to proteins. This groundbreaking work could speed the delivery of potential new drugs and improve existing ones.

19 Feb 2006

New real-time test for Chlamydia and Gonorrhea

Abbott today announced that a highly sensitive new test for the simultaneous detection of the sexually transmitted pathogens Chlamydia trachomatis (CT) and Neissera gonorrhoeae (NG) has received CE Mark certification, allowing it to be marketed in the European Union.

23 Jan 2006

Robotic microbial protein analysis

Microorganisms have potential as living factories for manufacturing drugs and biochemical products. Rapid mass screening methods are needed to identify new species. A new robotic system also provides useful data for genetic engineering.

15 Dec 2005

Researchers develop new method for facile identification of proteins in bacterial cells

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed a new method for identifying specific proteins in whole cell extracts of microorganisms using traditional peptide mass fingerprinting (PMF).

4 May 2005

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Nanogen issued new patent for active biological sample preparation

Nanogen announced today that it was issued U.S. Patent No. 6,824,740, "Apparatus for Active Biological Sample Preparation," by the U.S. Patent and Trademark Office.

6 Dec 2004

Nanogen announces clinical diagnostic to simultaneously detect multiple respiratory viruses

Nanogen announced today that it is developing new analyte specific reagents (ASRs) for clinical reference laboratories to develop and validate a single test to detect six of the most common respiratory viruses.

10 Nov 2004

Microfluidics help lab-on-a-chip development skyrocket

Lab-on-a-chip (LOC) development has skyrocketed in the last couple of years due to constant efforts in harnessing microfluidics and µTAS to improve the LOC design and function. The distinct advantages that they bestow on applications are pushing the commercial potential of LOCs.

28 Sep 2004

New service-oriented laboratory focused on bioanalysis and pharmacokinetics

Oregon Health & Science University researchers will more quickly move benchtop discoveries toward drug discoveries with the help of a new, service-oriented laboratory focused on bioanalysis and pharmacokinetics.

11 Aug 2004

Protein identification gets a speed boost

But the labor intensity of the procedure is now a thing of the past for researchers in the Oregon Health & Science University School of Medicine. The Proteomics Shared Resource, an unassuming but state-of-the-art lab on the fifth floor of OHSU's Medical Research Building, can process more than three times as many protein samples in half a day, and much of it can be done by one person.

14 Apr 2004