Sarcoma News and Research

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Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

Viruses designed to target and kill cancer cells could boost the effectiveness of chemotherapy to the arms and legs and help avoid amputation, a new study reports.

22 Jul 2014

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that China's Food and Drug Administration has approved the Company's application to conduct a Phase II clinical trial in triple-negative breast cancer (TNBC) patients in China for its proprietary drug candidate, ENMD-2076.

21 Jul 2014

Fla. hospitals on the hook for $267 million in Medicaid overpayment

The federal government says the hospitals were paid too much, and it wants the entire overage back this year. That is a tough demand for two of the state's safety-net hospitals. Meanwhile, a Florida teen battling cancer hits Capitol Hill to lobby for funding for Medicaid and other children's programs.

8 Jul 2014

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that its orally-active, Aurora A/angiogenic kinase inhibitor, ENMD-2076, has received Orphan Drug designation from the U.S. Food and Drug Administration for the treatment of hepatocellular carcinoma (HCC).

7 Jul 2014

Interactions with other infections can trigger herpes virus to reactivate, shows research

The famous slogan is "A diamond is forever," but that phrase might be better suited to herpes: Unlike most viruses, which succumb to the immune system's attack, herpes remains in the body forever, lying in wait, sometimes reactivating years later.

27 Jun 2014

Gene partnership may be fueling cancer spread in as much as 20% of cancers

A key cancer-causing gene, responsible for up to 20 percent of cancers, may have a weak spot in its armor, according to new research from the Masonic Cancer Center, University of Minnesota.

25 Jun 2014

New method to help patients with cancer, genetic conditions, neurological disorders

UT Arlington physics researchers may have developed a way to use laser technology to deliver drug and gene therapy at the cellular level without damaging surrounding tissue. The method eventually could help patients suffering from genetic conditions, cancers and neurological diseases.

25 Jun 2014

Clusters of protein linked to cancer warp cell membranes

Supercomputer simulations have shown that clusters of a protein linked to cancer warp cell membranes, according to scientists at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

24 Jun 2014

Small molecule in pregnant women's urine apparently blocks cancer growth

University of Montreal scientists have identified a small molecule found in pregnant women's urine that apparently blocks the growth of several types of cancers, including AIDS-related Kaposi's sarcoma, which currently has no cure.

24 Jun 2014

Clinical trial shows that selumetinib drug can delay progression of metastatic uveal melanoma

For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye.

20 Jun 2014

Researchers discover new class of tumor

This is the story of two perfectly harmless genes. By themselves, PAX3 and MAML3 don't cause any problems. However, when they combine during an abnormal but recurring chromosomal mismatch, they can be dangerous.

11 Jun 2014

Scientists unravel how herpesviruses fight against our immune system

How the virus does this was unknown until now. The scientists from the HZI research group "Viral Immune Modulation" under the leadership of Prof. Melanie Brinkmann have now been able to show that the virus is actively preventing activation of the innate immune system through Toll-like receptors.

9 Jun 2014

Immune Design begins treatment in LV305 Phase 1 clinical trial for cancer

Immune Design, a clinical-stage immunotherapy company focused on the development of novel immune-based therapies for cancer and other chronic conditions, today announced treatment of the first patient in a Phase 1 clinical trial of LV305, an immuno-oncology investigational agent from the company's DCVexTM lentiviral vector platform.

5 Jun 2014

Scientists reproduce chromosomal modifications in human cells that cause certain cancer

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro Nacional de Investigaciones Oncol-gicas (CNIO) have succeeded in reproducing, in human cells, the chromosomal translocations that cause two types of cancer: acute myeloid leukemia and Ewing's sarcoma.

5 Jun 2014

Researchers reproduce tumor chromosomal translocations in human cells

Scientists from the Spanish National Cancer Research Centre and the Spanish National Cardiovascular Research Centre have been able to reproduce, for the first time in human cells, chromosomal translocations associated with two types of cancer: acute myeloid leukaemia and Ewing's sarcoma.

4 Jun 2014

Researchers analysis adjuvant chemotherapy's impact on overall survival in patients with stage III STS

Fox Chase Cancer Center researchers have carried out the first retrospective analysis of adjuvant chemotherapy's impact on overall survival in patients with stage III soft tissue sarcomas (STS), adjusted for socioeconomic status and other variables.

31 May 2014

CytRx announces Phase 2b clinical trial results of aldoxorubicin in subjects with metastatic STS

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced updated results from its ongoing multicenter, randomized, open-label global Phase 2b clinical trial investigating the efficacy and safety of aldoxorubicin compared with doxorubicin as first-line therapy in subjects with metastatic, locally advanced or unresectable soft tissue sarcomas.

28 May 2014

Socioeconomic status appears to influence type of cancer a person may develop

A new analysis has found that certain cancers are more concentrated in areas with high poverty, while other cancers arise more often in wealthy regions. Also, areas with higher poverty had lower cancer incidence and higher mortality than areas with lower poverty.

28 May 2014

New analysis finds that certain cancers are more concentrated in areas with high poverty

28 May 2014

EntreMed reports net loss of $1.5M in first quarter 2014

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, today reported financial results for the three months ended March 31, 2014.

15 May 2014

Sarcoma News and Research

Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

Fla. hospitals on the hook for $267 million in Medicaid overpayment

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

Interactions with other infections can trigger herpes virus to reactivate, shows research

Gene partnership may be fueling cancer spread in as much as 20% of cancers

New method to help patients with cancer, genetic conditions, neurological disorders

Clusters of protein linked to cancer warp cell membranes

Small molecule in pregnant women's urine apparently blocks cancer growth

Clinical trial shows that selumetinib drug can delay progression of metastatic uveal melanoma

Researchers discover new class of tumor

Scientists unravel how herpesviruses fight against our immune system

Immune Design begins treatment in LV305 Phase 1 clinical trial for cancer

Scientists reproduce chromosomal modifications in human cells that cause certain cancer

Researchers reproduce tumor chromosomal translocations in human cells

Researchers analysis adjuvant chemotherapy's impact on overall survival in patients with stage III STS

CytRx announces Phase 2b clinical trial results of aldoxorubicin in subjects with metastatic STS

Socioeconomic status appears to influence type of cancer a person may develop

New analysis finds that certain cancers are more concentrated in areas with high poverty

EntreMed reports net loss of $1.5M in first quarter 2014

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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