Sarcopenia News and Research

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Sarcopenic obesity independently associated with an increased prevalence of dementia

Obesity, an increasingly prevalent lifestyle disease, often occurs along with poor muscle mass. This condition, called sarcopenic obesity, is evaluated based on the patients' body mass index (BMI) and handgrip strength.

26 May 2022

Mice live longer with nasal gene therapy

In a recent study published in the Proceedings of the National Academy of Sciences journal, researchers assessed the efficiency of a novel intranasal and injectable therapy in improving life expectancy.

17 May 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency.

22 Mar 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Study reveals link between muscular dystrophy and sphingolipids

In a new study, the group of Johan Auwerx at EPFL's School of Life Sciences has made the first connection between muscular dystrophy and sphingolipids, a group of bioactive lipids. The study is published in Science Advances.

29 Jan 2022

Simple, inexpensive method to predict the risk of functional disability in older people

Researchers at the Federal University of São Carlos in the state of São Paulo, Brazil, in partnership with colleagues at University College London in the UK have discovered an efficient, simple and inexpensive method of predicting the risk of functional disability in older people.

21 Dec 2021

Sarcopenia and COVID-19

The present study attempts to investigate if sarcopenia, which is a condition where there is loss of skeletal muscle mass and function, may result in poor clinical outcomes in COVID-19 patients.

13 Dec 2021

Lack of protein in the diet of women over 65 linked to sarcopenia and sarcopenic obesity

Different institutions, including the University of Valencia (UV), have studied the relationship between sarcopenia (loss of muscle mass in older people) and obesity derived from this condition with a lack of protein in the diet of women over 65 years of age.

4 Dec 2021

Study finds early stages of sarcopenia could be counteracted with timely interventions

Weakening muscles are a natural part of the ageing process, but for some people with a condition called sarcopenia the decline is abnormally fast.

30 Nov 2021

Older women with sarcopenia less likely to experience hot flashes

The loss of muscle mass is a natural part of aging. Older women with sarcopenia (age-related loss of muscle mass and function) are at an increased risk of reduced mobility, diminished quality of life, heart disease, and fall-related injuries.

10 Nov 2021

Green tea extract and cocoa-supplemented diets improve survival rate of aging mice

Aging-US published "Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system" which reported that green tea extract (GTE) and cocoa-supplemented diets significantly improved the survival rate of mice.

1 Sep 2021

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Analysis of medical data from around 1800 65-year-old residents of Kobe, a large Japanese city, has shown that at least 3% have possible sarcopenia (*1), revealing that the risks are higher in those who are underweight and don't exercise enough.

24 Aug 2021

New discovery provides clues to elucidate the pathogenesis of muscle diseases

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body.

6 Jul 2021

Professor Cyrus Cooper receives ECTS Steven Boonen Clinical Research award

The International Osteoporosis Foundation is delighted to announce that the European Calcified Tissue Society (ECTS) has presented the prestigious 2021 ECTS Steven Boonen Clinical Research Award to its President, Professor Cyrus Cooper.

7 May 2021

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected.

26 Apr 2021

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Scientists have produced a comprehensive roadmap of muscle aging in mice that could be used to find treatments that prevent decline in muscle mobility and function, according to a report published today in eLife.

20 Apr 2021

Stem cell therapy could help restore debilitating age-related muscle loss

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

23 Mar 2021

Hormone known to prevent weight gain can help maintain healthy muscles in mice

A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice.

23 Feb 2021

New genetic analysis reveals biological causes of muscle weakness in older people

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

11 Feb 2021