Schizoaffective Disorder News and Research

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Negative symptoms and cognition ‘relatively independent’ in schizophrenia

Diminished expression, a core negative symptom in people with schizophrenia, is significantly correlated with an array of cognitive functions, research by a Hong Kong team shows.

3 Jan 2014

Resting-state connectivity and metabolism dissociated in schizophrenia

A neuroimaging study suggests that patients with schizophrenia have difficulty deactivating the default mode network, rather than having increased absolute metabolic activity.

2 Jan 2014

Rates of smoking, drinking and drug use are higher among people with psychotic disorders

In the largest ever assessment of substance use among people with severe psychiatric illness, researchers at Washington University School of Medicine in St. Louis and the University of Southern California have found that rates of smoking, drinking and drug use are significantly higher among those who have psychotic disorders than among those in the general population.

2 Jan 2014

Brain network disruption crosses psychosis diagnostic boundaries

Disruption of cortical information processing occurs in patients with psychosis regardless of whether they have a psychotic or affective diagnosis, research shows.

6 Dec 2013

Early natural history of bipolar disorder mapped

A longitudinal study of children of parents with bipolar disorder gives insights into the developmental trajectory of the condition, which researchers say should prove valuable in guiding future intervention and prevention efforts.

28 Nov 2013

Gray matter changes reflect psychosis burden

Changes in gray matter volume may be associated with psychosis burden rather than clinical diagnosis, research suggests.

14 Nov 2013

Novel approach confirms dysfunctional energy production in schizophrenia

A method of directly assessing creatine kinase in the brain provides “direct and compelling” evidence for abnormal bioenergetics in the brains of patients with schizophrenia, say the study authors.

12 Nov 2013

Mood disorder subtypes remain in the family

Psychosis, mania, and depression are unlikely to have shared hereditary causes, report researchers in Molecular Psychiatry.

8 Nov 2013

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Reviva Pharmaceuticals, Inc., a privately held pharmaceutical company focused on the discovery and development of new, safer and highly effective therapies for chronic indications, announced today the successful completion of an End-of-Phase 2 meeting with the Food and Drug Administration for its lead, new investigational antipsychotic drug, RP5063.

5 Nov 2013

Left-handers more likely to suffer from psychotic disorders

Researchers have long studied the connections between hand dominance and different aspects of the human brain. A new study out today in SAGE Open finds that among those with mental illnesses, left-handers are more likely to suffer from psychotic disorders such as schizophrenia than mood disorders.

31 Oct 2013

Psychosis prediction model could facilitate early intervention

A integrated model has shown “outstanding” ability to predict the transition to psychosis in clinically high-risk patients, report investigators in Schizophrenia Bulletin.

25 Oct 2013

Cash rewards encourage antipsychotic injection adherence

Offering “modest” financial incentives to patients receiving maintenance antipsychotic treatment by depot injection can encourage them to adhere to the regimen, shows a randomized trial.

15 Oct 2013

Kraepelin distinctions back in favor

Modern statistical methods support Kraepelin’s original distinction between schizophrenia and bipolar disorder, but not the more recent schizoaffective disorder category, say researchers.

11 Oct 2013

Genetic score backs schizophrenia spectrum

Researchers report that polygenic scores derived from one well-characterized cohort of schizophrenia patients correspond to clinical diagnostic categories in another.

3 Sep 2013

Weekend reading: Mental illness stigma, health insurance mazes and female libido

Linneah sat at a desk at the Center for Sexual Medicine at Sheppard Pratt in the suburbs of Baltimore and filled out a questionnaire. She read briskly, making swift checks beside her selected answers, and when she was finished, she handed the pages across the desk to Martina Miller, who gave her a round of pills.

24 May 2013