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New fluid biomarker may one day detect ALS and FTD before symptoms appear

Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.

18 Mar 2024

Global health burden of neurological conditions is much greater than previously understood, study reveals

Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and ageing of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors.

18 Mar 2024

Study highlights growing burden of neurological disorders worldwide

Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer's disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and aging of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors.

15 Mar 2024

Microfluidic chips advance neurodegenerative disease research

Researchers review the role of microfluidic chip models in understanding neurodegenerative diseases, offering insights into the disease mechanisms and potential for drug development through innovative lab-on-a-chip technologies.

14 Mar 2024

Concussion from explosive blasts may induce Alzheimer's biomarkers in middle-aged veterans

Middle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid similar to people who develop Alzheimer's disease, according to a new study published in the March 13, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

14 Mar 2024

Groundbreaking study unveils new insights into neurodegenerative disorder symptoms

Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing.

14 Mar 2024

Study reveals TDP-43 protein's key role in blood vessel formation and integrity

Defects in the blood vessel network of the central nervous system have been linked to early symptoms of neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

13 Mar 2024

Exploring the power of diet: A new frontier in disease management and cancer treatment

The therapeutic potential of and molecular mechanisms through which dietary interventions impact a wide range of human diseases.

13 Mar 2024

NIH study uncovers vulnerable sites on Epstein-Barr virus protein

Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.

12 Mar 2024

Study highlights potential therapeutic target for immune-related disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

11 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Stroke risk linked to sleep apnea may vary for Black people and white people

The risk of stroke tied to sleep apnea may vary for Black people and white people, according to a study published in the March 6, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Mar 2024

Essential tremor associated with increased risk of dementia

Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024.

6 Mar 2024

Key brain cells linked to repetitive behaviors in psychiatric diseases

Crym-expressing astrocytes in the striatum have been identified as key regulators of behaviors often seen in neuropsychiatric diseases, opening up new avenues for targeted therapies.

6 Mar 2024

Noninvasive gamma therapy may hold promise for treating chemo brain

Patients undergoing chemotherapy often experience cognitive effects such as memory impairment and difficulty concentrating -; a condition commonly known as "chemo brain."

6 Mar 2024

Study reveals safety of MS drugs during breastfeeding in child's early years of life

Certain medications for multiple sclerosis (MS) called monoclonal antibodies, taken while breastfeeding, may not affect the development of a child during the first three years of life, according to a preliminary study released today, March 4, 2024.

4 Mar 2024

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior.

4 Mar 2024

People with sleep apnea more likely to have memory or thinking problems

People who experience sleep apnea may be more likely to also have memory or thinking problems, according to a preliminary study released today, March 3, 2024, that will be presented at the American Academy of Neurology's 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.

4 Mar 2024

Tandem cycling boosts well-being for Parkinson's patients and care partners

Pedaling on a stationary bicycle built for two may improve the health and well-being for both people with Parkinson's disease and their care partners, according to a small, preliminary study released today, February 29, 2024, that will be presented at the American Academy of Neurology's 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.

29 Feb 2024

Sclerosis News and Research

New fluid biomarker may one day detect ALS and FTD before symptoms appear

Global health burden of neurological conditions is much greater than previously understood, study reveals

Study highlights growing burden of neurological disorders worldwide

Microfluidic chips advance neurodegenerative disease research

Concussion from explosive blasts may induce Alzheimer's biomarkers in middle-aged veterans

Groundbreaking study unveils new insights into neurodegenerative disorder symptoms

Study reveals TDP-43 protein's key role in blood vessel formation and integrity

Exploring the power of diet: A new frontier in disease management and cancer treatment

NIH study uncovers vulnerable sites on Epstein-Barr virus protein

Study highlights potential therapeutic target for immune-related disorders

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Stroke risk linked to sleep apnea may vary for Black people and white people

Essential tremor associated with increased risk of dementia

Key brain cells linked to repetitive behaviors in psychiatric diseases

Noninvasive gamma therapy may hold promise for treating chemo brain

Study reveals safety of MS drugs during breastfeeding in child's early years of life

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

People with sleep apnea more likely to have memory or thinking problems

Tandem cycling boosts well-being for Parkinson's patients and care partners

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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