Severe Acute Respiratory News and Research

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Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Study highlights the ability of the Vaxzevria vaccine in inducing robust mucosal antibody responses, especially in COVID-19-recovered individuals, showcasing a notable defense against various SARS-CoV-2 variants. However, it emphasizes the need for booster doses to enhance anti-SARS-CoV-2 mucosal immunity, especially in infection-naïve individuals, to broaden protection against emerging viral variants.

28 Sep 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Researchers discovered molnupiravir-associated mutational signatures in SARS-CoV-2 genomes.

27 Sep 2023

Long COVID's biological blueprint: new study offers promising insights

Researchers designed a cross-sectional study to investigate the biological underpinnings of “Long COVID”, the post-acute infection syndrome triggered by SARS-CoV-2.

27 Sep 2023

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

Researchers characterized the gut microbiota composition associated with the durability of COVID-19 vaccine-induced immunity.

27 Sep 2023

How the COVID-19 pandemic affected mental well-being of UK secondary school students

Researchers evaluated the impact of COVID-19 on the mental health of secondary school children in the UK.

26 Sep 2023

One health wake-up call: London's river data highlights environmental perils

The largest-ever spatiotemporal monitoring of chemicals/contaminants of emerging concern (CECs) in London waterways.

26 Sep 2023

Hospitalized COVID-19 patients face triple the risk of multiorgan damage, study reveals

Researchers in the U.K. find that patients hospitalized with COVID-19 face a higher medium-term risk of multiorgan abnormalities, revealed through multiorgan MRI scans. The study emphasizes the urgency for comprehensive post-hospitalization care, as these abnormalities are associated with persistent mental and physical health impairments.

25 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

One gene variant could be a shield against severe COVID-19 lung damage

Researchers identify a specific genetic variant, rs2204985, linked to less severe lung involvement and a stronger immune response in COVID-19 patients with severe pneumonia. The study suggests that understanding this genetic marker could help identify high-risk individuals and enhance strategies for prevention and treatment.

25 Sep 2023

The power of nanobodies: How they impact COVID-19 immune response

The structures of 340 antibodies (Abs) and 83 nanobodies.

25 Sep 2023

COVID-19 pushed upstate New Yorkers to embrace backyard farming

During the COVID-19 pandemic, upstate New Yorkers turned to backyard and wild food production to gain more control over their food supply, according to a study by Cornell University. The research highlights how the pandemic-related disruptions in conventional food supply chains led to a significant uptick in gardening, poultry rearing, and foraging as a strategy to improve food security.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Could creatine supplementation be the answer to post-COVID-19 fatigue?

In a recent study published in the journal Food Science & Nutrition, researchers investigated creatine supplementations as a potential intervention strategy to attenuate the clinical symptoms of post-COVID-19 fatigue syndrome.

22 Sep 2023

Can COVID-19 vaccines turn the tide on long-haul symptoms?

The study finds that COVID-19 vaccination can significantly reduce symptoms and improve well-being in patients suffering from post-COVID-19 conditions (PCC). Vaccination also lowered systemic markers of inflammation but did not entirely eliminate persistent SARS-CoV-2 antigens, which may continue to contribute to inflammation.

22 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

Has the COVID-19 pandemic made young adults less fit?

A recent study in Scientific Reports reveals that one year after the onset of the COVID-19 pandemic, young adults experienced significant declines in physical fitness parameters, including explosive power, aerobic and anaerobic capacities, and weight. These changes could have serious health implications, especially for those with diabetes and cardiovascular diseases, underscoring the importance of promoting physical activity during and after pandemics.

20 Sep 2023

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

The association between BNT162b2 vaccine and (COVID-19)-related ambulatory visits.

20 Sep 2023

How did exposure to news on COVID-19 through social platforms impact psychological health and behavior?

The relationship between news on the COVID-19 pandemic through social media, feelings of fear and anxiety, and behavior.

18 Sep 2023

Severe Acute Respiratory News and Research

Vaxzevria vaccine boosts mucosal immunity in COVID-19 recovered

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Long COVID's biological blueprint: new study offers promising insights

Could baseline gut microbiota predict the immune responses elicited by COVID-19 vaccines?

How the COVID-19 pandemic affected mental well-being of UK secondary school students

One health wake-up call: London's river data highlights environmental perils

Hospitalized COVID-19 patients face triple the risk of multiorgan damage, study reveals

Intranasal vaccine shows promise against COVID variants in hamsters

One gene variant could be a shield against severe COVID-19 lung damage

The power of nanobodies: How they impact COVID-19 immune response

COVID-19 pushed upstate New Yorkers to embrace backyard farming

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Could creatine supplementation be the answer to post-COVID-19 fatigue?

Can COVID-19 vaccines turn the tide on long-haul symptoms?

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

Has the COVID-19 pandemic made young adults less fit?

Vaccine impact: BNT162b2 and pediatric COVID-19 ambulatory visits in kids under 5

How did exposure to news on COVID-19 through social platforms impact psychological health and behavior?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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