Shigella News and Research

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Study shows septin proteins detect and kill gut pathogen, Shigella

Using state-of-the art technologies to image human cells and study infection at the level of a single bacterial cell, the research team, led by the London School of Hygiene & Tropical Medicine, has uncovered the strongest evidence yet that septins take Shigella prisoner.

13 Dec 2018

Researchers shed new light on how to combat Shiga and ricin toxins

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They've figured out how Clostridium difficile's most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969.

11 Dec 2018

New study launched in Burkina Faso to test typhoid conjugate vaccine

A new study has been launched in Burkina Faso for Bharat Biotech's typhoid conjugate vaccine. It is the second clinical study underway in Africa for the vaccine and the first in West Africa.

4 Dec 2018

Simple, inexpensive test quickly detects antibiotic-resistant 'superbugs'

When you get sick, you want the right treatment fast. But certain infectious microbes are experts at evading the very anti-bacterial drugs designed to fight them.

16 Oct 2018

Novel 3-in-1 vaccine designed against traveler’s diarrhea

A first-ever vaccine designed to deliver a one-two-three punch against the main causes of traveler's diarrhea worldwide may result from new research published by a University of Guelph chemist.

11 Oct 2018

Unrecognized childhood infections far greater threat than previously realized

Children around the world are suffering from unnoticed infections that are stunting their growth and mental development, new research from an international coalition of scientists reveals.

10 Oct 2018

Gut microbial signature may help identify causes of chronic malnutrition in children

Chronic malnutrition, usually associated with an inflammation of the small intestine, affects one in every four children under the age of five. It is the leading cause of child mortality in low-income countries and is also responsible for severe stunting.

24 Aug 2018

New report highlights continuing threat of antimicrobial resistance by dangerous bacteria

Carbapenemase-producing Enterobacteriaceae (also known as CPE) and Neisseria gonorrhoeae continue to be the most commonly reported organisms with critical resistances to antimicrobials across Australia, according to a national report released today.

22 Aug 2018

Study finds diverse mix of bacteria in the urine of kidney disease patients

The urine of kidney disease patients contains a diverse mix of bacteria such as Staphylococcus and Streptococcus, according to a study by researchers at Loyola Medicine and Loyola University Chicago.

4 May 2018

NYC mice carry deadly bacteria and viruses

Almost all types of housing and living facilities house mice. Researchers have found in their year-long study on New York City mice that many of these carry on them deadly bacteria and viruses. These bacteria could be resistant to antibiotics and thus they may cause life threatening infections in humans.

18 Apr 2018

Bacterial 'gene swapping' affects emergence and spread of infectious diseases

A new study by scientists at the University of Liverpool documents, for the first time, how the ability of bacteria to swap genetic material with each other can directly affect the emergence and spread of globally important infectious diseases.

17 Apr 2018

Researchers report functional and transferable gene responsible for colistin resistance

A researcher at LSTM, working with a team of Chinese investigators, have reported that the gene responsible for resistance to a last resort antibiotic, colistin, is functional and transferable in Shigella flexneri, one of the leading causes of diarrhea worldwide.

2 Mar 2018

UAB expert provides in-depth understanding of food-borne illnesses

Parties and gatherings are typically centered around food, making it important to know the do's and don'ts of handling food.

13 Oct 2017

Symprove could offer safe and efficient solution to control pathogenic bacteria

Leading food technology company, Symprove Ltd, has demonstrated with three breakthrough studies that their formula has the unique ability to have an antagonistic effect on pathogenic bacteria such as C. difficile, Escherichia coli (AIEC), Shigella sonnei and MRSA.

4 Oct 2017

New antibiotic development slowing - warns World Health Organization

According to a new report from the World Health Organization (WHO) released yesterday, antibiotics development at present is not at par with the rising antimicrobial resistance worldwide and soon the demand may outgrow the supply. The WHO warns that this could mean that pathogens causing these infections could mean a great threat for humans in the coming years.

19 Sep 2017

UM SOM research identifies four pathogens responsible for majority of diarrheal illnesses

Each year, more than half a million deaths among children under five years of age around the world are caused by diarrheal diseases -- largely due to insufficient access to adequate hygiene, sanitation and clean drinking water.

11 Sep 2017

UM SOM awarded $2.47 million grant to develop vaccine against Shigella, ETEC infections

The University of Maryland School of Medicine has been awarded a three-year, $2.47 million grant from the National Institute of Allergy and Infectious Diseases to develop a vaccine to protect against Shigella and Enterotoxigenic Escherichia coli (ETEC), pathogens which are among the leading causes of diarrheal diseases in young children in developing countries and a common cause of "traveler's diarrhea" among travelers to these countries.

3 Aug 2017

MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

The precise mechanism used by Legionella bacteria to escape the body's defences has been unpicked in intricate detail and is described for the first time in the journal eLife.

11 Apr 2017

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015.

23 Dec 2016