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Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier - a tiny capsule specially designed to pass through cell membranes and deliver its anti-cancer drug to the cancer cell.

18 Nov 2010

Researchers unveil novel oncogene associated with uveal melanoma

An international, multi-center study has revealed the discovery of a novel oncogene that is associated with uveal melanoma, the most common form of eye cancer.

18 Nov 2010

Statins activate bacterial-killing properties of white blood cells

Widely prescribed for their cholesterol-lowering properties, recent clinical research indicates that statins can produce a second, significant health benefit: lowering the risk of severe bacterial infections such as pneumonia and sepsis.

18 Nov 2010

13-hour lifesaving heart/liver transplant performed on pulmonary atresia patient

A 28-year old man from Georgia, David Krech, is recovering from a rare, lifesaving heart/liver transplant on October 15 at the University of Maryland Medical Center. The 13-hour operation followed a five-month journey as he awaited a suitable heart and liver donor.

17 Nov 2010

New dressing materials and plasters indicate pathological changes in the skin

Wounds have to be regularly checked, to make sure any complications in the healing process are detected at an early stage. A new material will make it possible to check wounds without changing the dressing: If an infection arises, the material changes its color.

17 Nov 2010

New technique to purify propolis

The healing properties of propolis a mixture of resin and wax made by honey bees to seal and sterilise their hives have been known for many years. But its use in medicine and food supplements has been limited because the sticky substance is not water soluble and has a strong, off-putting smell.

17 Nov 2010

Study finds phenotypic plasticity among melanoma cells

University of Michigan researchers have determined that most types of melanoma cells can form malignant tumors, providing new evidence that the deadliest form of skin cancer does not conform to the increasingly popular cancer stem cell model.

17 Nov 2010

NIH awards $10 million to advance technology for painless influenza vaccine delivery patch

The National Institutes of Health (NIH) has awarded $10 million to the Georgia Institute of Technology, Emory University and PATH, a Seattle-based nonprofit organization, to advance a technology for the painless, self-administration of flu vaccine using patches containing tiny microneedles that dissolve into the skin.

17 Nov 2010

Pharmigene receives patent for methods to detect genetic alleles in SJS and TENS

Pharmigene, a leader in advancing personalized medicine and reducing severe adverse reactions to drugs through genetic-based diagnostic solutions, announced it has been granted patents in the United States, Europe, Australia, Singapore and Taiwan. The patents cover methods to detect the presence of key genetic alleles in individual patients being considered for treatment with drugs that have been linked to the development of adverse drug reactions including Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

17 Nov 2010

UMass, PolyMedix receive Phase 2 STTR contract to conduct test on antimicrobial compounds

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat infectious diseases and acute cardiovascular disorders, and the University of Massachusetts, Amherst (UMass), have received a Phase 2 Small Business Technology Transfer (STTR) contract in the amount of $750,000.

17 Nov 2010

Stratatech receives SBIR grant to develop anti-infective living human skin substitute

Stratatech Corp., a privately-held regenerative medicine company, today announced that it has been awarded a $3.5 million Fast-Track SBIR grant to expand the development of its anti-infective living human skin substitute.

17 Nov 2010

ALLOZYNE's AZ17 antagonist shows positive data for treatment of autoimmune diseases

ALLOZYNE Inc. announced today positive data from preclinical studies evaluating AZ17 which is a novel bispecific Th17 antagonist that inhibits the differentiation and effector function of human Th17 cells in vivo.

17 Nov 2010

Urgent need for bowel cancer screening funding

Bowel Cancer Foundation chairman, Graham Newstead feeling frustrated at the federal government’s indecision on bowel cancer screening funds has expressed his dismay. He suggested that the government should ensure the future funding for the screening test that has saved an estimated 11,000 lives since screening was introduced in 2006.

16 Nov 2010

Researchers develop human cell-based model of Rett syndrome

A groundbreaking study published Friday in the leading scientific journal, Cell, revealed that a team of investigators had successfully generated nerve cells using skin cells from four individuals with Rett syndrome. The study, funded in part by IRSF, was led by Dr. Alysson Muotri at the University of California, San Diego--a leading researcher in the stem cell field.

16 Nov 2010

Research suggests targeting spleen may promote healing of spinal cord injury

The spleen, an organ that helps the body fight infections, might also be a source of the cells that end up doing more harm than good at the site of a spinal cord injury, new research suggests.

16 Nov 2010

Millions of Americans suffer unnecessarily with itchy, gritty, watery eyes, say allergists

Millions of Americans suffer unnecessarily with itchy, gritty, watery eyes, according to allergists at the annual scientific meeting of the American College of Allergy, Asthma and Immunology in Phoenix, Nov. 11-16. The underdiagnosis, undertreatment and self-treatment of eye allergies may seriously diminish quality of life, allergists say.

16 Nov 2010

Prolonged use of cell phone increases nickel allergy

Chatting endlessly on your cell phone can lead to an allergic reaction to the nickel in your phone, according to allergists at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Phoenix, Nov. 11-16. From cosmetics to jewelry, body piercings to tattoos, allergies can lurk in unlikely places, allergists say.

15 Nov 2010

Inovio third quarter total revenue decreases from $3.6 million to $1.3 million

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended September 30, 2010.

15 Nov 2010

Study shows patient-specific factors delay skin cancer treatment

If detected early, nonmelanoma skin cancers (primarily basal cell and squamous cell carcinomas, the two most common forms of skin cancer) can be easily treated. But when left untreated, these skin cancers can grow and even spread, causing considerably more harm than if they were treated upon initial detection. Now, a new study finds that denial is the top reason why patients delay seeking treatment for skin cancer and shows that this delay results in larger, more serious, skin cancers.

15 Nov 2010

New protocol reduces radiation exposure in pediatric electrophysiology procedures

A protocol that uses continuous real-time radiation monitoring, low-dose imaging programs and requires physician awareness of radiation dose, significantly reduced radiation exposure during electrophysiology procedures and catheter ablations to diagnose and treat heart arrhythmias in children, according to research presented at the American Heart Association's Scientific Sessions 2010.

15 Nov 2010

Skin News and Research

Anti-cancer drug smuggled using a nanocarrier past protective blood-brain barrier into brain tumours

Researchers unveil novel oncogene associated with uveal melanoma

Statins activate bacterial-killing properties of white blood cells

13-hour lifesaving heart/liver transplant performed on pulmonary atresia patient

New dressing materials and plasters indicate pathological changes in the skin

New technique to purify propolis

Study finds phenotypic plasticity among melanoma cells

NIH awards $10 million to advance technology for painless influenza vaccine delivery patch

Pharmigene receives patent for methods to detect genetic alleles in SJS and TENS

UMass, PolyMedix receive Phase 2 STTR contract to conduct test on antimicrobial compounds

Stratatech receives SBIR grant to develop anti-infective living human skin substitute

ALLOZYNE's AZ17 antagonist shows positive data for treatment of autoimmune diseases

Urgent need for bowel cancer screening funding

Researchers develop human cell-based model of Rett syndrome

Research suggests targeting spleen may promote healing of spinal cord injury

Millions of Americans suffer unnecessarily with itchy, gritty, watery eyes, say allergists

Prolonged use of cell phone increases nickel allergy

Inovio third quarter total revenue decreases from $3.6 million to $1.3 million

Study shows patient-specific factors delay skin cancer treatment

New protocol reduces radiation exposure in pediatric electrophysiology procedures

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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