Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Bortezomib extends lung cancer survival

Adding the new molecularly targeted agent bortezomib to a standard chemotherapy regimen of gemcitabine and carboplatin prolongs survival in patients with advanced non-small cell lung cancer, according to results from a phase II trial.

9 Jun 2006

Sunitinib malate shows promise against advanced form of lung cancer

Results of a multi-center clinical study of a drug currently approved for treatment of kidney cancer indicate that it may also be effective for people with recurrent and advanced lung cancer.

5 Jun 2006

New data show Enzastaurin's activity across multiple cancer cell lines

Eli Lilly and Company's enzastaurin, an investigational, multi-targeted therapy that is currently the focus of two global Phase III clinical trials, one for the treatment of glioblastoma and one in non-Hodgkin's lymphoma

5 Jun 2006

Significant changes in tumor growth can be detected through short interval follow-up

These growths may have important clinical implications in the management of patients, enabling early discontinuation of potentially toxic chemotherapy drugs.

4 May 2006

Non-Smokers with lung cancer respond better to treatment than smokers

Smoking history contributes to poor outcomes in the treatment of lung cancer, according to a new study. Non-small cell lung cancer (NSCLC) lung cancer patients who have never smoked before in their life have better overall survival rates and respond better to chemotherapy than current or former smokers.

24 Apr 2006

Kidney treatments may be improved with new understanding of cell death mechanism

Finding how two proteins conspire to get kidney cells to self-destruct when oxygen supplies are low may one day improve dismal mortality rates for ischemic renal failure, researchers say.

23 Apr 2006

Most cancer victims unaware of anti-angiogenesis

According to a new survey nine out of ten patients battling cancer in Europe have never heard of the major breakthrough in cancer treatment, known as anti-angiogenesis.

From The University of Manchester 28 Mar 2006

Lilly launches phase III trial of Enzastaurin

One of the deadliest and rarest forms of cancer is the focus of a Phase III study initiated by Eli Lilly and Company today.

9 Mar 2006

C-reactive protein helps identify progressive precancerous lesions in the lung

C-reactive protein (CRP), a biomarker for inflammation in the blood, can help to identify individuals whose abnormal precancerous lesions will advance closer to invasive lung cancer.

1 Mar 2006

Genzyme launches test to monitor Gleevec resistance

Genzyme Corporation has announced the availability of an important new test to monitor drug resistance in chronic myeloid leukemia (CML) patients who are treated with Gleevec (imatinib mesylate).

13 Feb 2006

Advocacy groups unite to make lung cancer in women a top priority

Women's health and lung cancer advocacy groups, led by the Society for Women's Health Research, vowed today to make lung cancer education and advocacy, especially among women, a top priority for their organizations in 2006 and beyond.

7 Feb 2006

Lower survival rates of blacks with lung cancer may be explained by access to care

New research suggests that the lower survival rates of blacks with lung cancer may be explained by access to care. The study, by Wake Forest University Baptist Medical Center researchers and colleagues is reported in the January issue of the Journal of Clinical Oncology.

5 Feb 2006

Radiation therapy cures lung cancer

According to the Global Lung Cancer Coalition, each year ten million people are diagnosed with lung cancer, and half of all patients die within a year of diagnosis.

24 Jan 2006

Palliative radiation cures some lung cancer patients

About one in a hundred patients with apparently incurable non-small cell lung cancer (NSCLC) survive five or more years after being given relatively small doses of radiation therapy (RT) meant to ease symptoms, according to a new study.

23 Jan 2006

TCF21 gene shown to be a tumor suppressor

Researchers have identified a new and unusual tumor suppressor gene that may be important in cancers of the lung and head and neck. The study shows that restoring the inactivated gene can slow the growth of tumor cells.

18 Jan 2006

Bexarotene shows promise in cancer treatment.

Researchers at Washington University School of Medicine in St. Louis now report that a compound related to vitamin A shows promise in preventing or slowing tumor growth in mice prone to lung cancer. The compound, called bexarotene, doesn't cause the severe skin irritations that have limited the use of other vitamin A derivatives in cancer therapies.

18 Jan 2006

Caspase 8 gene halts spread of aggressive childhood cancer

A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.

6 Jan 2006

Targeted cancer therapies: Another step forward

While it is clear that the treatment of cancer has already begun to undergo a paradigm shift with the inclusion of innovative targeted therapies into current regimens, it would be wrong to assume these products will entirely replace traditional chemotherapy as the standard treatment for cancer sufferers.

22 Dec 2005

Targeted cancer therapies: Another step forward

22 Dec 2005

New and promising antibody profiling technique to test for non-small cell lung cancer cases

Biomedical scientists have revealed a new and promising antibody profiling technique that provides a high degree of early diagnostic accuracy for non-small cell lung cancer cases.

26 Nov 2005