Small Intestine News and Research

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Roux-en-Y gastric bypass surgery can lead to effective weight loss

Imperial College London. The findings, published in the American Journal of Physiology—Regulatory, Integrative, and Comparative Physiology, suggest a new mechanism by which some types of bariatric surgery lead to long-term weight loss.

28 Jul 2011

Gut microflora may influence obesity treatments

Obesity in the United States is reaching ever more alarming proportions, posing a severe menace to public health and exacerbating a crisis in health care costs both domestically and worldwide.

27 Jul 2011

Researchers create tissue-engineered small intestine in mice

Researchers at The Saban Research Institute of Children's Hospital Los Angeles have successfully created a tissue-engineered small intestine in mice that replicates the intestinal structures of natural intestine-a necessary first step toward someday applying this regenerative medicine technique to humans.

6 Jul 2011

Women more likely to survive after major gastrointestinal surgeries than men

In the first study to consider the impact of gender on patient outcomes in major gastrointestinal surgeries, researchers at UC San Diego Health System have found that women are more likely to survive after the procedure than men.

1 Jul 2011

Abbott reports positive interim results from LCIG Phase III open-label study for advanced Parkinson's disease

Interim efficacy and safety results from a long-term, 54-week, Phase III open-label study of Abbott's investigational treatment for advanced Parkinson's disease showed that patients treated with levodopa-carbidopa intestinal gel (LCIG) for 12 weeks reported a decrease in "off" time and an increase in "on" time without troublesome dyskinesias.

9 Jun 2011

Niiki Pharma to present NKP-1339 Phase I trial against metastatic cancer at ASCO 2011

Niiki Pharma announced today that it will present interim data from the ongoing Phase I clinical study for its lead product, NKP-1339, at the 2011 American Society for Clinical Oncology meeting in Chicago, IL.

2 Jun 2011

Transarterial embolization an effective alternative to endoscopy for acute peptic ulcer bleeding

Researchers from China report that in patients with peptic ulcer bleeding in whom endoscopy failed to control the bleeding, transarterial embolization is a safe procedure which reduces the need for surgery without increasing overall mortality and is associated with few complications.

24 May 2011

New data on personalized approaches for skin, ovarian and lung cancer to be presented at ASCO meeting

Genentech, a member of the Roche Group, today announced that data showing new personalized approaches for people with skin and lung cancer, plus new data with Avastin in ovarian cancer, will be presented at the 47th Annual Meeting of the American Society of Clinical Oncology.

18 May 2011

Irritable Bowel Syndrome linked to bacterial overgrowth, food poisoning

Cedars-Sinai researchers have reported two advances in the understanding of Irritable Bowel Syndrome, the most common gastrointestinal disorder in the United States, affecting an estimated 30 million people.

12 May 2011

Insight into probiotic bacteria can help improve intestinal disease treatments

The gut may need bacteria to provide a little bit of oxidative stress to stay healthy, new research suggests. Probiotic bacteria promote healing of the intestinal lining in mice by inducing the production of reactive oxygen species, researchers at Emory University School of Medicine have shown.

11 May 2011

Nexvax2- coeliac disease vaccine shows promising results in Phase I clinical trial

The world's first potential vaccine for coeliac disease has shown promising results for treating coeliac disease in a Phase I clinical trial and is expected to move to Phase II trials within the next year.

10 May 2011

Fecal transplant procedures performed at Sinai Hospital

Sudhir Dutta, M.D., head of the Division of Gastroenterology at Sinai Hospital, performed fecal transplant procedures for two patients with severe clostridium difficile (C. difficile) colitis that did not respond to routine antibiotic and other treatments. C. difficile causes symptoms ranging from mild diarrhea to more serious, sometimes life threatening colon inflammation.

5 May 2011

Health Canada grants SQI license to market IgX PLEX Celiac Panel

SQI Diagnostics Inc., a medical systems automation company focused on evolving laboratory-based autoimmune biomarker testing, today announced it has received a license from Health Canada permitting the Company to market its IgX PLEX™ Celiac Panel, a quantitative 4-plex panel, which will run on SQI's automated SQiDworks™ Diagnostics Platform.

29 Apr 2011

Eli Lilly receives FDA complete response letter for liprotamase NDA

Eli Lilly and Company has received a complete response letter from the U.S. Food and Drug Administration for its New Drug Application for liprotamase, a non-porcine pancreatic enzyme replacement therapy, under investigation for the treatment of exocrine pancreatic insufficiency.

16 Apr 2011

Ubiquitine D gene may be linked to celiac disease

Celiac disease (CD) involves intolerance to gluten and, consequently, suffering chronic illness in the small intestine. It is a genetic disorder, the immunological indications of which can be traced in the human body prior to the everyday activities of future sufferers being affected. For example, persons with genetic antecedents for CD develop antibodies against the gene tTG (the enzyme known as tissue transglutaminase), even before the illness becomes active, due to a cell reaction against gluten.

5 Apr 2011

UTHealth initiates enrollment in study on promising surgical procedure for management of type 2 diabetes

Physicians at The University of Texas Health Science Center at Houston (UTHealth) have begun enrollment for a pilot study on a promising surgical approach for the management of Type 2 diabetes.

1 Apr 2011

New Image to build dairy plant in New Zealand

Health and wellness products manufacturer New Image Group is to help meet global demand for more nutritional milk products with the building of a multi-million dollar, spray drying plant in New Zealand.

31 Mar 2011

20-year data shows bariatric surgery to reduce risk of heart attack and stroke in diabetics

In the longest study of its kind, bariatric surgery has been shown to reduce the risk of heart attack and stroke in patients with diabetes. These results and other groundbreaking research were presented at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.

31 Mar 2011

Inflammatory bowel disease in children - Delays in diagnosis common

Once a medical rarity in children, inflammatory bowel disease today is increasingly common in kids, but many of them may not be diagnosed in a timely manner, according to experts from the Pediatric Inflammatory Bowel Disease Center at Johns Hopkins Children’s Center.

28 Mar 2011

Scientists discover hormone pathway that can lead to new diabetes treatment

Researchers at UT Southwestern Medical Center have discovered a hormone pathway that potentially could lead to new ways of treating type 1 diabetes independent of insulin, long thought to be the sole regulator of carbohydrates in the liver.

25 Mar 2011