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Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have identified a cell metabolism process found in men with diabetes and metastatic prostate cancer that could one day lead to improved testing and treatments for Black men with these diseases.

15 Aug 2023

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19.

10 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Duke researchers develop potent antibiotic against drug-resistant superbugs

A scientific journey decades in the making at Duke University has found a new antibiotic strategy to defeat gram-negative bacteria like Salmonella, Pseudomonas and E. coli, the culprits in many urinary tract infections (UTIs).

9 Aug 2023

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

In neuroinflammation, immune cells such as leukocytes cross the blood-brain barrier. One key to this is the gelatinases matrix metalloproteinase (MMP)-2 and -9. Until now, the substrates of these enzymes involved in the process were unknown.

9 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

Are teicoplanin-non-susceptible Staphylococcus epidermidis strains increasing?

Researchers elucidated the incidence patterns of teicoplanin-non-susceptible Staphylococcus epidermidis (Teico-NS S. epidermidis) over six years.

8 Aug 2023

Physical exercise mitigates risk of sleep disturbances due to cadmium exposure

Researchers examine the correlation between blood cadmium exposure, physical activity, and sleep disturbances.

8 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Neoantigen discovery sheds light on cancer immunogenicity

Researchers reported a proteogenomic approach to investigate fresh solid melanoma tumor material.

4 Aug 2023

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers used a UHPLC and mass spectrometry-based Metabolon platform to identify and characterize circulating metabolites associated with depression.

1 Aug 2023

Study illuminates new connections between diet and immunity

A metabolic by-product that is more prevalent during fasting may supercharge immune cells as they fight infection and disease, reports an early stage study by Van Andel Institute scientists and collaborators.

28 Jul 2023

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University Singapore (NTU Singapore) and Massachusetts Institute of Technology (MIT), have discovered a new stress signaling system that enables bacteria cells to adapt and protect themselves against the immune system and certain antibiotics.

24 Jul 2023

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple negative breast cancer (TNBC) to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis.

21 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

Spectrometry News and Research

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

Duke researchers develop potent antibiotic against drug-resistant superbugs

Mass spectrometry-based secretome approach reveals key players in astroglial barrier function

What are some recent advancements in proteomics-driven pancreatic oncology research?

Are teicoplanin-non-susceptible Staphylococcus epidermidis strains increasing?

Physical exercise mitigates risk of sleep disturbances due to cadmium exposure

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Neoantigen discovery sheds light on cancer immunogenicity

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Study illuminates new connections between diet and immunity

Breakthrough stress sensor discovery reveals new mechanism of antimicrobial resistance

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Using single-cell mass spectrometry to study antimicrobial treatment failure

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Study reveals potential target for repairing beta-cell dysfunction in Type 2 diabetes

AI and infection control: preventing infectious disease outbreaks and pandemics

Study identifies blood proteins linked to mortality in severe burns

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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