Spike Protein News and Research

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SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

In a recent study posted to the medRxiv* preprint server, researchers explored the association between circulating coronavirus disease 2019 (COVID-19) antigens and post-COVID-19 sequelae (long COVID).

20 Jun 2022

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

In a recent study posted to the bioRxiv* preprint server, researchers at Weill Cornell Medical College assessed the cleavability of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and related coronaviruses by several proteases of the host.

19 Jun 2022

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

A team of scientists from China has recently deciphered the structural basis of comparatively higher binding affinity of two Omicron sub-variants, namely B.1.1 and B.2, for human angiotensin-converting enzyme 2 (ACE2).

17 Jun 2022

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Researchers assessed the impact of SARS-CoV-2-neutralizing antibodies on the SARS-CoV-2 Omicron variant.

17 Jun 2022

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

In a recent study posted to the bioRxiv* pre-print server, researchers developed a novel Binding Activated Tandem split enzyme (BAT) biosensor for the detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

16 Jun 2022

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

Over-the-counter COVID tests can quickly show whether you are infected with SARS-CoV-2. But if you have a positive result, there's no equivalent at-home test to assess how long you're protected against reinfection.

16 Jun 2022

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

Researchers found that immune-boosting by SARS-CoV-2 Omicron variant is contingent on prior COVID-19 history.

16 Jun 2022

SARS-CoV-2 damages cilia

Researchers determine whether the interaction between ORF10 and ZYG11B promotes the dissemination of SARS-CoV-2.

15 Jun 2022

Study describes how coronavirus subverts a host cell pathway to infect human cells

An international team of scientists, led by the University of Bristol, has been investigating how the SARS-CoV-2 virus, the coronavirus responsible for the COVID-19 pandemic, manipulates host proteins to penetrate into human cells.

15 Jun 2022

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

Researchers assessed the interactions between SARS-CoV-2 and ACE2.

14 Jun 2022

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Of the three groups of rotavirus that cause gastroenteritis in people, called groups A, B and C, groups A and C affect mostly children and are the best characterized.

9 Jun 2022

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

In a recent study posted to the bioRxiv* pre-print server, researchers examined how the interaction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 8 (ORF8) protein with host dendritic cells (DCs) induced cytokine storm.

8 Jun 2022

Zoonotic origins of seasonal human coronaviruses

In a recent study posted to the bioRxiv* preprint server, investigators analyzed the evolution and origin of seasonal human coronaviruses (sHCoVs).

8 Jun 2022

Where did Omicron's unique spike gene insertion originate?

In a recent study posted to the medRxiv* pre-print server, scientists at nference Labs investigated the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron's unique spike (S) gene insertion ins214EPE.

8 Jun 2022

A new coronavirus found in Swedish bank voles

Researchers report the discovery of the Gimso virus, a novel betacoronavirus in a bank vole from Grimso, Sweden

7 Jun 2022

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Researchers assessed the interactions between carbon nanotubes and SARS-CoV-2.

7 Jun 2022

Omicron lineage spike proteins use ACE2 receptors more efficiently

A recent study posted to the bioRxiv* preprint server demonstrated various traits, including the entry pathways and sensitivity to vaccination-elicited antibody responses by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants.

7 Jun 2022

Spike Protein News and Research

SARS-CoV-2 spike circulating in most long COVID 12 months post-diagnosis

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

Study explains the structural basis of higher ACE2 binding affinity of Omicron sub-variants

Scientists explore effectiveness of neutralizing antibodies against SARS-CoV-2 Omicron variant

Novel luminescent biosensor detects SARS-CoV-2 spike protein using cell phone camera

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

Prior spike protein exposures shape protection against SARS-CoV-2 Omicron variant

SARS-CoV-2 damages cilia

Study describes how coronavirus subverts a host cell pathway to infect human cells

The evolution of the physicochemical mechanism of interaction of the SARS-CoV-2 spike protein with ACE2

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

SARS-CoV-2 ORF8 protein binds to dendritic cells and induces a hyper-inflammatory cytokine storm

Zoonotic origins of seasonal human coronaviruses

Where did Omicron's unique spike gene insertion originate?

A new coronavirus found in Swedish bank voles

Molecular modeling techniques describe the process of interaction between nanotubes and the main structures of SARS-CoV-2

Omicron lineage spike proteins use ACE2 receptors more efficiently

A system for detecting emerging SARS-CoV-2 variants

The effects of accessory protein mutations and other non-spike mutations on SARS-CoV-2 pathogenesis

Study analyzes how four types of COVID-19 vaccines prepare the body to fight SARS-CoV-2

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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