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‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

Emerging nanomaterials-based biosensor for detecting SARS-CoV-2

A new study aimed to highlight the different smart and emerging nanomaterials used to detect SARS-CoV-2.

19 Jan 2022

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Researchers have discovered a new way to induce immunity against the RBD.

19 Jan 2022

Three doses Of Pfizer-BioNTech vaccine could offer sufficient level of protection from Omicron

A new study that evaluated the effectiveness of the BNT162b2 (Pfizer-BioNTech) vaccine against the Omicron variant indicates that three doses could offer a sufficient level of protection from disease caused by the Omicron variant.

18 Jan 2022

Study finds COVID booster maintains strong T cell response against Omicron

New study results posted to the medRxiv* preprint server found that COVID vaccine boosters increase immunity by enhancing T cell immune memory. In the face of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) Omicron variant, vaccinated people who had received a third booster shot maintained high T cell responses than people with naturally acquired immunity or vaccine-induced immunity from two doses of the SARS‑CoV‑2 vaccine.

18 Jan 2022

New perspective on SARS-CoV-2 breakthrough infections and booster shot restoration of vaccine efficacy

A recent article published in the journal Science explains how SARS-CoV-2 variants can bypass vaccine-induced immune defenses. However, immunity is restorable with a booster shot. The paper's authors outlined the importance of a booster shot in maintaining immunity and preventing severe infection.

18 Jan 2022

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

In this study, the researchers not only elucidate the recent bioconjugated nanomaterials for targeted diagnosis of SARS-CoV-2, but they also provide the rationale behind these developments by discussing the mechanisms and approaches.

18 Jan 2022

Comparison of antibody responses and vaccine effectiveness in healthcare workers post-primary COVID-19 vaccination

The authors highlight that they have shown that boosted individuals are significantly more protected against SARS-CoV-2 infection than any other group

18 Jan 2022

Antibody responses to COVID-19 mRNA vaccines in a cohort of healthcare workers

Researchers have been investigating the vaccine response of healthcare workers from specific vaccines to different variants.

18 Jan 2022

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

A recent preprint discusses using a combinatorial phage-display library approach to COVIID-19 antibodies.

18 Jan 2022

Immune responses in Omicron breakthrough COVID-19

A recent study examined the question as to whether vaccination protects against Omicron infection by assessing breakthrough infection rates in participants at a superspreader event.

18 Jan 2022

Transmission of Omicron in a quarantine hotel between two vaccinated individuals across a corridor

A recent study has reported a community outbreak of imported SARS-CoV-2 Beta variant, owing to intra-hotel transmission in a DQH.

17 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

New research assesses the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation in response to SARS-CoV-2 and its spike protein, and the effects of this exposure in the presence of a-synuclein protein aggregate fibrils.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

In a new study, researchers used a simple phenomenological model to investigate the role of immunocompromised hosts in SARS-CoV-2 antigenic development.

17 Jan 2022

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Researchers have been investigating the Omicron epidemic in Japan and have recently released an early report on the infectious period of the disease.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

A new paper published in the journal JCI Insight reports on the differential levels of immunity achieved in those with and without a history of prior infection with the virus following one and two doses of the earliest vaccines to be approved for emergency use.

17 Jan 2022

Mutations in SARS-CoV-2 Omicron variant promote cell binding

Researchers in Germany, based on their recent study published in the journal ChemBioChem, have proposed that the elevated occurrence of positively charged amino acids in specific domains of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) Omicron variant spike protein improves viral binding to cellular negatively charged receptors aiding in enhanced infectiousness.

16 Jan 2022

Spike Protein News and Research

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

Emerging nanomaterials-based biosensor for detecting SARS-CoV-2

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Three doses Of Pfizer-BioNTech vaccine could offer sufficient level of protection from Omicron

Study finds COVID booster maintains strong T cell response against Omicron

New perspective on SARS-CoV-2 breakthrough infections and booster shot restoration of vaccine efficacy

Applications of bioconjugated nanomaterials in SARS-CoV-2 diagnostics

Comparison of antibody responses and vaccine effectiveness in healthcare workers post-primary COVID-19 vaccination

Antibody responses to COVID-19 mRNA vaccines in a cohort of healthcare workers

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

Immune responses in Omicron breakthrough COVID-19

Transmission of Omicron in a quarantine hotel between two vaccinated individuals across a corridor

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Better global health equality could prevent emergence of future SARS-CoV-2 variants of concern

Study suggests vaccinated Omicron cases are unlikely to shed infectious virus 10 days after diagnosis or symptom onset

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

Mutations in SARS-CoV-2 Omicron variant promote cell binding

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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