Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Research may hold key to maintaining embryonic stem cells in lab

In a new study that could transform embryonic stem cell (ES cell) research, scientists at UT Southwestern Medical Center have discovered why mouse ES cells can be easily grown in a laboratory while other mammalian ES cells are difficult, if not impossible, to maintain.

9 Jul 2009

Family Research Council President says NIH stem cell guidelines ethically irresponsible

Today, Family Research Council President Tony Perkins responded to the National Institutes of Health (NIH) guidelines implementing President Obama's executive order for federal funding of human embryonic stem cell research (ESCR). President Obama's order and the NIH guidelines remove life-protecting limits on federal funding of embryonic stem cell research.

7 Jul 2009

Obama administration releases final rules on stem cell research

The Obama administration released final regulations governing stem cell research on Monday. The New York Times reports that the rules will allow many older stem cell lines to be eligible for federally financed research.

7 Jul 2009

Potential new target for acute myeloid leukemia

Dr. John Dick, Senior Scientist at the Ontario Cancer Institute, the research arm of Princess Margaret Hospital, co-led a multinational team that has developed the first leukemia therapy that targets a protein, CD123, on the surface of cancer stem cells that drive acute myeloid leukemia (AML), which is an aggressive disease with a poor outcome.

6 Jul 2009

MicroRNAs hold promise for treating diseases in blood vessels

A newly discovered mechanism controls whether muscle cells in blood vessels hasten the development of both atherosclerosis and Alzheimer's disease, according to an article published online today in the journal Nature.

5 Jul 2009

Bioethicists lead call for public debates on future uses of stem cells

More than 40 scientists, bioethicists, lawyers and science journal editors are calling on their colleagues, policy makers and the public to begin developing guidelines for the research and reproductive use of stem cell-derived eggs and sperm, even though such use may be a decade or more away.

2 Jul 2009

Even moderate exercise helps keep the brain healthy

Scientists at the University of Queensland (UQ) say they have found that exercise helps keep the brain healthy and even moderate exercise directly increases the number of stem cells in the ageing brain.

28 Jun 2009

Clinical trial raises hope for Australian diabetics to be insulin free

A clinical trial for a new treatment for type 1 diabetes which potentially eliminates the need for daily insulin injections will commence in New Zealand by Australian company Living Cell Technologies (LCT).

23 Jun 2009

Woman's placenta new source for harvesting stem cells

A groundbreaking study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new avenue for harvesting stem cells from a woman's placenta, or more specifically the discarded placentas of healthy newborns.

23 Jun 2009

Scientists edit genes in human stem cells

Researchers at the Johns Hopkins School of Medicine have successfully edited the genome of human- induced pluripotent stem cells, making possible the future development of patient-specific stem cell therapies. Reporting this week in Cell Stem Cell, the team altered a gene responsible for causing the rare blood disease paroxysmal nocturnal hemoglobinuria, or PNH, establishing for the first time a useful system to learn more about the disease.

18 Jun 2009

Fallopian tubes: a new source of multipotent adult mesenchymal stem cells

Human tissues normally discarded after surgical procedures could be a rich additional source of stem cells for regenerative medicine. New research from BioMed Central's open access Journal of Translational Medicine shows for the first time that human fallopian tubes are abundant in mesenchymal stem cells which have the potential of becoming a variety of cell types.

17 Jun 2009

Cancer immunotherapy can use small numbers of ‘stem-like’ immune cells to destroy large tumors in mice

A new approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice, according to a study by researchers at the National Cancer Institute, a part of the National Institutes of Health. This work represents an important advance in the development of immunotherapy for cancer and appears online June 14, 2009 in Nature Medicine.

15 Jun 2009

Don't stress when the going gets tough - you'll go gray!

A study by Japanese researchers has revealed that a certain kind of stress damages the hair - they say "genotoxic stress" damages DNA by depleting the melanocyte stem cells (MSCs) within hair follicles that are responsible for making the pigment-producing cells.

14 Jun 2009

Genotoxic stress makes your hair go gray

Those pesky graying hairs that tend to crop up with age really are signs of stress, reveals a new report in the June 12 issue of Cell, a Cell Press publication.

12 Jun 2009

Gene activity reveals dynamic stroma microenvironment in prostate cancer

As stroma - the supportive framework of the prostate gland - react to prostate cancer, changes in the expression of genes occur that induce the formation of new structures such as blood vessels, nerves and parts of nerves, said researchers at Baylor College of Medicine in a report that appears in the current issue of the journal Clinical Cancer Research.

9 Jun 2009

Scientists create pig stem cells

Scientists have managed to induce cells from pigs to transform into pluripotent stem cells - cells that, like embryonic stem cells, are capable of developing into any type of cell in the body. It is the first time in the world that this has been achieved using somatic cells (cells that are not sperm or egg cells) from any animal with hooves (known as ungulates).

2 Jun 2009

Gene that stops or suppress cancer plays a role in cancer stem cells

A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast cancer stem cells.

1 Jun 2009

Linking microRNAs with cells that regulate the immune system could lead to new disease therapies

Linking genetic material microRNAs with cells that regulate the immune system could one day lead to new therapies for treating cancer, infections and autoimmune diseases, according to a Henry Ford Hospital study.

1 Jun 2009

Glioblastoma may originate in neural stem cells

University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points the way to more effective future treatments and a way to screen for the disease early.

1 Jun 2009

Protein abundant in embryonic stem cells offers a new cancer target

A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston.

1 Jun 2009