Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Researchers find genetic "signature" that accurately identifies colon cancer

Researchers at Jefferson Medical College in Philadelphia have uncovered a genetic "signature" that accurately identifies colon cancer--a key, they hope, to better understand how the cancer develops.

13 Apr 2006

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

A study led by researchers from the Howard Hughes Medical Institute has found that dasatinib provides significant benefit in chronic myeloid leukemia (CML) patients resistant to Gleevec. (imatinib), according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

11 Apr 2006

Stem cells can repair damaged spinal tissue and help restore function in rats with spinal cord injuries

Each year, some 11,000 Americans sustain spinal cord injury, most often in traffic accidents. Costs of the condition approach $10 billion per year.

11 Apr 2006

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

A single dose of adult donor stem cells given to animals that have neurological damage similar to that experienced by adults with a stroke or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say.

11 Apr 2006

Minimal nutritional requirements for growing and maintaining human embryonic stem cells

Researchers at Yale have established the minimal nutritional requirements for growing and maintaining human embryonic stem cells, a recipe that is critical for clinical application and for developmental studies, according to a report in the Proceedings of the National Academy of Sciences.

11 Apr 2006

Adult stem cells can be used to make new tendon or ligament tissue

Weekend athletes who overexert themselves running or playing basketball may one day reap the benefits of research at the Hebrew University of Jerusalem that shows that adult stem cells can be used to make new tendon or ligament tissue.

4 Apr 2006

Custom-made bladders produced from patients' own cells

Scientists in the U.S. have produced custom-made bladders grown from patients' own cells which have been have been successfully transplanted and function well.

4 Apr 2006

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer, researchers from Duke University Medical Center and John Hopkins University School of Medicine have found.

4 Apr 2006

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Inflammation, cartilage and bone erosions, joint destruction--that's the typical progression of arthritis and most rheumatic diseases.

4 Apr 2006

Weill Cornell experts publish review of genetic medicine

In an article published in the April issue of Nature Reviews Genetics, two experts at the Weill Medical College of Cornell University sum up the achievements, challenges and promise of a burgeoning field: genetic medicine.

3 Apr 2006

New device could cut chemotherapy deaths

A new method of delivering chemotherapy to cancer patients without incurring side effects such as hair loss and vomiting is being developed.

31 Mar 2006

Mouse Brain Gene Expression Map at St. Jude - powerful new tool for studying brain development

Scientists at St. Jude Children's Research Hospital have given investigators around the world free access to a powerful tool for studying brain development.

28 Mar 2006

Novel therapy for chronic graft-versus-host disease

A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.

28 Mar 2006

Procedure cures some diabetic mice, but not in the way previously reported

Researchers attempting to reproduce a controversial 2003 mouse experiment suggestive of a cure for type 1 diabetes have found evidence that the experimental procedure does eliminate diabetic symptoms in a small fraction of the mice exposed to it.

28 Mar 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.

27 Mar 2006

Cell therapy slows progression of metachromatic leukodystrophy

In an important discovery, scientists have demonstrated that the progression of a type of genetic brain disease is slowed and symptoms are improved in mice that received cell transplants.

23 Mar 2006

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Recent advances in gene therapy, stem cells and other promising applications are offering new hope for patients and helping orthopaedic surgeons provide state-of-the-art treatment for various frame-related conditions.

23 Mar 2006

Zoologists succeed for the first time in transforming stem cells in freshwater polyps

Stem cells are versatile all-rounders. In the medical field, high hopes are resting on these miracle workers. However, we still understand very little about them.

21 Mar 2006

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

21 Mar 2006

Stem Cells News and Research

Further Reading

Researchers find genetic "signature" that accurately identifies colon cancer

Dasatinib provides significant benefit in chronic myeloid leukemia patients resistant to Gleevec

Stem cells can repair damaged spinal tissue and help restore function in rats with spinal cord injuries

Single dose of stem cells produce robust behavioral recovery in animal models for stroke, cerebral palsy

Minimal nutritional requirements for growing and maintaining human embryonic stem cells

Adult stem cells can be used to make new tendon or ligament tissue

Custom-made bladders produced from patients' own cells

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis

Weill Cornell experts publish review of genetic medicine

New device could cut chemotherapy deaths

Mouse Brain Gene Expression Map at St. Jude - powerful new tool for studying brain development

Novel therapy for chronic graft-versus-host disease

Procedure cures some diabetic mice, but not in the way previously reported

Study provides a boost for efforts to reverse type-1 diabetes

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Cell therapy slows progression of metachromatic leukodystrophy

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Zoologists succeed for the first time in transforming stem cells in freshwater polyps

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

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