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Brain organoids reveal how alcohol exposure impairs the development and functioning of new brain cells

Alcohol consumption during pregnancy poses significant peril to the healthy development of the unborn child. There is no known safe amount of alcohol during pregnancy.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Researchers identified β-cyclodextrins (β-CDs) as a safe and cost-effective drug against SARS-CoV-2 with a broad spectrum of activity.

18 Nov 2022

Intermediate levels of indoor relative humidity shown to improve COVID-19 outcomes globally

In a new study, researchers found that indoor relative humidity modulates the severity of COVID-19 outbreaks, and intermediate RHs between 40 to 60% are robustly associated with better COVID-19 outcomes.

18 Nov 2022

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

In this interview, News-Medical talks to Dr Javier Yugueros-Marcos, Head of the Antimicrobial Resistance and Veterinary Products Department at the World Organisation for Animal Health, about how the world can work together to promote the sustainable and responsible use of antimicrobials.

18 Nov 2022

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Nov 2022

Study identifies risk factors and symptom clusters associated with long-COVID

A recent study posted to medRxiv* preprint server evaluated risk factors associated with long COVID.

17 Nov 2022

COVID-19 carries a much higher risk of epilepsy and seizures than influenza

COVID-19 increases risk of both seizures and epilepsy as compared to influenza infection

17 Nov 2022

Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potency

In a recent study posted to the bioRxiv* preprint server, researchers developed bispecific antibodies (bsAbs), neutralizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

17 Nov 2022

WHO releases new data on worldwide influenza activity

The latest WHO report updated up to 30 October 2022 has data categorized by influenza transmission zones, i.e., countries/regions with similar influenza transmission patterns.

17 Nov 2022

What is the immune protection generated by SARS-CoV-2 Delta and Omicron BA.1 and BA.2 against Omicron BA.4 and BA.5?

Researchers evaluated immune protection conferred by previous SARS-CoV-2 Delta variant and Omicron BA.1/BA.2 subvariant infections and updated vaccines against Omicron BA.4/5 infections and associated hospitalizations.

17 Nov 2022

Evaluating differences in viral and symptom rebounds between Paxlovid-treated and untreated COVID-19 patients

Researchers evaluated differences in viral and symptom rebounds between Paxlovid-treated and untreated coronavirus disease 2019 (COVID-19) patients.

17 Nov 2022

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

Researchers compared the presence of post–coronavirus disease 2019 (COVID-19) symptoms among hospitalized and non-hospitalized patients in Spain.

17 Nov 2022

Protection afforded by SARS-CoV-2 infection against reinfection when Omicron BA.5 was the dominating subvariant in Scania county, Sweden

Researchers from Sweden conducted a cohort study to evaluate the protection granted by previous SARS-CoV-2 Omicron subvariant infections against reinfections among individuals vaccinated between June and August 2022.

17 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

Researchers explored the efficiency of a macrocyclic peptide in inhibiting the SARS-CoV-2 spike protein.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Study uncovers new rules for lineage progression

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls puberty onset and reproductive behavior to sustain the breeding population.

17 Nov 2022

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

17 Nov 2022

Syndrome News and Research

Brain organoids reveal how alcohol exposure impairs the development and functioning of new brain cells

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

Scientists explore bat sarbecovirus isolation in Japan

β-cyclodextrin family found to be promising and cost-effective antiviral agents against SARS-CoV-2

Intermediate levels of indoor relative humidity shown to improve COVID-19 outcomes globally

World Antimicrobial Awareness Week: Preventing Antimicrobial Resistance Together

How gut microbes influence immune response to SARS-CoV-2

Study identifies risk factors and symptom clusters associated with long-COVID

COVID-19 carries a much higher risk of epilepsy and seizures than influenza

Bispecific antibodies neutralize Sarbecoviruses with increased breadth and potency

WHO releases new data on worldwide influenza activity

What is the immune protection generated by SARS-CoV-2 Delta and Omicron BA.1 and BA.2 against Omicron BA.4 and BA.5?

Evaluating differences in viral and symptom rebounds between Paxlovid-treated and untreated COVID-19 patients

Comparing post–COVID-19 symptoms two years after SARS-CoV-2 infection

Protection afforded by SARS-CoV-2 infection against reinfection when Omicron BA.5 was the dominating subvariant in Scania county, Sweden

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers identify a conserved site on SARS-CoV-2 spike that a broadly neutralizing macrocyclic peptide can target

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Study uncovers new rules for lineage progression

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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