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Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Although two RNA-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates elicited similar, dose-dependent neutralizing antibody titers in both younger and older adults, a recent study by researchers from the U.S. and Germany has shown that BNT162b2 is associated with less systemic reactogenicity in elderly individuals – supporting its selection for further phase 2/3 clinical trials. The study is currently available on medRxiv* preprint server.

23 Aug 2020

Scientific review on on link between air pollution and COVID-19

Researchers at Harvard T. H. Chan School of Public Health, Harvard University, and the Dana-Farber Cancer Institute have conducted a “state-of-the-science” review of the evidence available on potential associations between exposure to air pollution and health outcomes in coronavirus disease 2019 (COVID-19).

23 Aug 2020

Raccoon dogs potential intermediate host for SARS-CoV-2

Researchers at the Friedrich Loeffler Institute in Germany have conducted a study demonstrating that raccoon dogs were a potential intermediate host in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

COVID-19 causes significant dilation of lung blood vessels, indicates study

A new pilot study from the Icahn School of Medicine at Mount Sinai suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries.

21 Aug 2020

Researchers compare COVID-19 transmission risk when singing, speaking and breathing

Now, a new study* set to determine if singing and playing of woodwind and brass instruments produce more respiratory droplets and aerosols than speaking. Further, they want to know if the size and temperature of the venue will make a difference in the accumulation of aerosol droplets in the air.

21 Aug 2020

Bioinformatics identifies key genes and cellular pathways in COVID-19

The COVID-19 pandemic is showing no signs of waning or extinction anytime soon. Now, a new study published on the preprint server bioRxiv* in August 2020 shows a new bioinformatics approach to studying the pathogenesis of this disease, by uncovering the differentially expressed genes (DEGs) and cell signaling pathways that cause the disease characteristics. This will help develop better therapies to counter the effects of these genes.

20 Aug 2020

No evidence of active SARS-CoV-2 in breastmilk of infected women

A recent study published in the journal JAMA in August 2020 suggests that SARS-CoV-2 RNA does not represent replication-competent virus and that breast milk may not be a source of infection for infants.

20 Aug 2020

Websites selling home-based COVID-19 testing kits providing inadequate or misleading information

In the UK and US, many websites are selling direct to user self-sampling and testing kits to detect SARS-CoV-2. Recently, a cross-sectional observational study was carried out to check the completeness and accuracy of information provided by these websites.

20 Aug 2020

New SARS-CoV-2 vaccine effective in macaques

Researchers from the biotechnology company Novavax in Gaithersburg, Maryland, have developed a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that successfully induces immunogenicity and protection against the virus in macaques.

20 Aug 2020

COVID-19 could compromise key element of immune response

Researchers at the University of Melbourne have made the unsettling discovery that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might compromise the activation of the CD8+ T-cell responses that would usually ameliorate disease and drive recovery in cases of respiratory disease.

20 Aug 2020

Whey protein from human breastmilk inhibits SARS-CoV-2 infection

Many scientists have reported the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy and the virus has been detected in breastmilk. Now a new study published on the preprint server bioRxiv* in August 2020 shows that whey protein in human breastmilk efficiently prevents infection with SARS-CoV-2 as well as post-entry viral replication.

20 Aug 2020

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Research from Chapman University provides new insight into the characteristics of crucial proteins within the ciliary membrane that play vital roles in human genetic diseases and cardiovascular functions.

20 Aug 2020

Scientists investigate the role of contractility and microbiota in chronic constipation

Chronic constipation (CC) remains a serious medical and social problem because the complexity of diagnosis, the lack of a single approach to treatment, and unsatisfactory treatment results.

20 Aug 2020

Children play a larger role in the community spread of COVID-19 than previously thought

In the most comprehensive study of COVID-19 pediatric patients to date, Massachusetts General Hospital (MGH) and Mass General Hospital for Children (MGHfC) researchers provide critical data showing that children play a larger role in the community spread of COVID-19 than previously thought

20 Aug 2020

Study shows why certain genetically predisposed individuals do not develop heart disease

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

20 Aug 2020

COVID-19 linked to type 1 diabetes and diabetic ketoacidosis in children

A team of researchers at Imperial College Healthcare NHS Trust and Imperial College London has found a link between COVID-19 and new-onset type 1 diabetes in children. The research is published in the journal Diabetes Care.

20 Aug 2020

SARS-CoV-2 hijacks antiviral factors to promote infection in human lung cells

Now, a new study published in the preprint server bioRxiv in August 2020 shows that under conditions resembling those in vivo, IFNs may promote efficient viral invasion instead.

20 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

Syndrome News and Research

Pfizer/BioNTech COVID-19 vaccine candidate BNT162b2 profiled for large scale clinical trials

Scientific review on on link between air pollution and COVID-19

Raccoon dogs potential intermediate host for SARS-CoV-2

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

COVID-19 causes significant dilation of lung blood vessels, indicates study

Researchers compare COVID-19 transmission risk when singing, speaking and breathing

Bioinformatics identifies key genes and cellular pathways in COVID-19

No evidence of active SARS-CoV-2 in breastmilk of infected women

Websites selling home-based COVID-19 testing kits providing inadequate or misleading information

New SARS-CoV-2 vaccine effective in macaques

COVID-19 could compromise key element of immune response

Whey protein from human breastmilk inhibits SARS-CoV-2 infection

Ciliary proteins play vital role in cardiovascular functions and genetic diseases

Scientists investigate the role of contractility and microbiota in chronic constipation

Children play a larger role in the community spread of COVID-19 than previously thought

Study shows why certain genetically predisposed individuals do not develop heart disease

COVID-19 linked to type 1 diabetes and diabetic ketoacidosis in children

SARS-CoV-2 hijacks antiviral factors to promote infection in human lung cells

Researchers develop vaccine for human herpesvirus 6B

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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