Synthetic Biology News and Research

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Using combinatorial libraries to engineer genetic circuits advances synthetic biology

Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.

22 Apr 2009

Researchers create gene circuit that permits precise tuning of a gene's expression in a cell

Researchers have crafted a gene circuit that permits precise tuning of a gene's expression in a cell, an advance that should allow for more accurate analysis of the gene's role in normal and abnormal cellular function.

11 Mar 2009

Synthetic biology extends anti-malaria drug artemisinin's effectiveness

In addition to providing a simple and much less expensive means of making artemisinin, the most powerful anti-malaria drug in use today, synthetic biology can also help to extend the effectiveness of this drug.

8 Mar 2009

Researchers discover mechanism that plays a role in the natural production of vitamin C

Researchers from Wageningen University, along with colleagues from the University of Groningen and the University of Pavia (Italy), have unravelled the mechanism that plays a role in the natural production of vitamin C.

17 Feb 2009

Researchers hunt for a hi-tech vaccine against Helicobacter pylori

Almost half of the world population is infected with bacteria Helicobacter pylori which colonizes stomach, causing gastritis and ulcers and is recognized by WHO as a type I carcinogen.

10 Dec 2008

Researchers generate synthetic SARS-like bat coronavirus

SARS - severe acute respiratory syndrome - alarmed the world five years ago as the first global pandemic of the 21st century.

25 Nov 2008

Systems biology brings hope of speeding up drug development

Almost every day brings news of an apparent breakthrough against cancer, infectious diseases, or metabolic conditions like diabetes, but these rarely translate into effective therapies or drugs, and even if they do clinical development usually takes well over a decade.

19 Nov 2008

New technologies improve supplies of drugs to combat malaria

Three emerging technologies have the potential to significantly improve supplies of drugs to combat malaria, according to a report published today.

18 Nov 2008

New drugs the next casualty of the credit crunch

Scientists at an international conference have been warned that the next casualty of the credit crunch could be new drugs.

27 Oct 2008

Synthetic Biology: funders move to address social and ethical challenges

The report of an independent review of social and ethical challenges associated with research into, and the application of, synthetic biology, is published (9 June).

10 Jun 2008

New projects to raise UK profile in synthetic biology

Four UK Research Councils have come together to announce funding for new projects designed to rapidly build the UK's expertise and capacity in the emerging field of synthetic biology.

30 May 2008

Interaction networks: the new path to drug discovery

Although the pharmaceutical industry has dedicated enormous research efforts over the last 50 years to identify new targets and develop new active ingredients, these efforts have met with limited success.

17 Apr 2008

Scientists synthesize DNA-based memory loop in yeast cells

Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology.

17 Sep 2007

Scientits devise dimmer swith to regulate gene expression in mammal cells

Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. Professor James Collins, Professor Charles Cantor and doctoral candidate Tara Deans invented the switch, which can be tuned to produce large or small quantities of protein, or none at all.

27 Jul 2007

Bacterial biofilms

In one of the first potential applications of synthetic biology, an emerging field that aims to design and build useful biomolecular systems, researchers from MIT and Boston University are engineering viruses to attack and destroy the surface biofilms that harbor harmful bacteria in the body and on industrial and medical devices.

10 Jul 2007

The future of engineering devices, systems and materials: made from bacteria?

Members of the public will get to see how revolutionary scientists and engineers are proposing to make counters, sensors, calculators and other devices out of living bacteria at this year's Royal Society Summer Science Exhibition.

3 Jul 2007

Call for global push to advance research in synthetic biology

With research backgrounds ranging from materials engineering to molecular biophysics, seventeen leading scientists issued a statement announcing that, much as the discovery of DNA and creation of the transistor revolutionized science, there is a new scientific field on the brink of revolutionizing our approach to problems ranging from eco-safe energy to outbreaks of malaria.

26 Jun 2007

Researchers equip E. coli with a "riboswitch" chemo-navigational system

Using an innovative method to control the movement of Escherichia coli in a chemical environment, Emory University scientists have opened the door to powerful new opportunities in drug delivery, environmental cleanup and synthetic biology.

11 May 2007

Scientists create leaner and meaner E. coli

By stripping the E. coli genome of vast tracts of its genetic material - hundreds of apparently inconsequential genes - a team of Wisconsin researchers has created a leaner and meaner version of the bacterium that is a workhorse of modern biology and industry.

3 May 2006

Researchers can now inexpensively program the chemical synthesis of entire genes on a single microchip

Devices the size of a pager now have greater capabilities than computers that once occupied an entire room. Similar advances are being made in the emerging field of synthetic biology at the University of Houston, now allowing researchers to inexpensively program the chemical synthesis of entire genes on a single microchip.

23 Dec 2004